BioRxiv 2025-02-06 Papers
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 使用基于高氧-BOLD的血容量测量来改进基于qBOLD的氧提取分数测量 | Stone, A. J. | N/A | Improving qBOLD based measures of oxygen extraction fraction using hyperoxia-BOLD derived measures of blood volume | |
| 全新鉴定通用的细胞力学基因特征 | Urbanska, M. | N/A | De novo identification of universal cell mechanics gene signatures | |
| 人类新皮层树突中信号传播速度的加快 | Olah, G. | N/A | Accelerated signal propagation speed in human neocortical dendrites | |
| 人类细胞中LbuCas13a介导的旁侧RNA切割的时间动态 | Bot, J. F. | N/A | Temporal dynamics of collateral RNA cleavage by LbuCas13a in human cells | |
| 使用布尔蕴含网络研究结直肠癌中的肿瘤相关巨噬细胞及其极化 | Dadlani, E. | N/A | Investigating tumor-associated macrophages and their polarization in colorectal cancer using Boolean implication networks | |
| 在清醒行为中的猕猴中观察到的伽马爆发皮层活动 | Acland, B. T. | N/A | Gamma-burst cortical activity in awake behaving macaques | |
| 视觉皮层中的曲率形成：我们如何进行采样？ | Nisar, I. | N/A | Curvature formation in the visual cortex: How do we sample? | |
| CXCR4和ACKR3构象景观的单分子分析揭示其独特的激活机制 | Schafer, C. T. | N/A | Distinct Activation Mechanisms of CXCR4 and ACKR3 Revealed by Single-Molecule Analysis of their Conformational Landscapes | |
| 饮酒与小鼠中央杏仁核中表达强啡肽的神经元钙活性增强有关。 | Lebonville, C. | N/A | Alcohol drinking is associated with greater calcium activity in mouse central amygdala dynorphin-expressing neurons | |
| 人脑中的几何形状规则性效应 | Sable-Meyer, M. | N/A | A geometric shape regularity effect in the human brain | |
| 在威胁处理过程中的脑动态与时空轨迹 | Misra, J. | N/A | Brain dynamics and spatiotemporal trajectories during threat processing | |
| 单细胞组学转录组特征分析（SCOTCH）：通过长读长单细胞RNA测序进行基因表达的异构体水平特征分析 | Xu, Z. | N/A | Single-Cell Omics for Transcriptome CHaracterization (SCOTCH): isoform-level characterization of gene expression through long-read single-cell RNA sequencing | |
| 老年人静息状态下大脑网络的分离程度与步行速度和工作记忆有关。 | Sato, S. D. | N/A | Resting state brain network segregation is associated with walking speed and working memory in older adults | |
| 使用Zarr在生物样本库规模上准备分析就绪的VCF | Czech, E. A. | N/A | Analysis-ready VCF at Biobank scale using Zarr | |
| 在学习过程中，丘脑核团与皮层网络之间功能连接的渐进性变化 | Jarrett, C. E. | N/A | Progressive changes in functional connectivity between thalamic nuclei and cortical networks across learning | |
| 一个新的用于估计同义替换选择压力的比较框架。 | Verdonk, H. | N/A | A new comparative framework for estimating selection on synonymous substitutions. | |
| 棕榈酰化Importin α通过与NuMA相互作用调控有丝分裂纺锤体定向 | Sutton, P. J. | N/A | Palmitoylated Importin α Regulates Mitotic Spindle Orientation Through Interaction with NuMA | |
| 对糖尿病-结核病共病患者肺免疫细胞的单细胞分析揭示了II型干扰素减少和Th17反应增强的现象。 | Chaudhary, S. | N/A | Single-cell profiling of the lung immune cells of diabetes-tuberculosis comorbidity reveals reduced type-II interferon and elevated Th17 responses. | |
| 材料特性与细胞效应之间的相互作用驱动了氧化石墨烯与癌细胞和非癌细胞之间不同的相互作用模式。 | Chen, Y. | N/A | Interplay between material properties and cellular effects drives distinct pattern of interaction of graphene oxide with cancer and non-cancer cells | |
| 谷氨酸棒状杆菌的系统代谢工程用于高效生产L-色氨酸 | Dong, Y. | N/A | Systems metabolic engineering of Corynebacterium glutamicum for efficient L-tryptophan production | |
| 利用蛋白质结构图嵌入预测错义变异的致病性 | Danner, M. | N/A | Utilizing protein structure graph embeddings to predict the pathogenicity of missense variants | |
| 在问题解决过程中，眼与手的协同运动揭示了层次化组织的规划过程。 | Eluchans, M. | N/A | Eye and hand coarticulation during problem solving reveals hierarchically organized planning | |
| 分泌性白细胞蛋白酶抑制剂影响伯氏疏螺旋体感染小鼠的关节周围炎症 | Yu, Q. | N/A | Secretory leukocyte protease inhibitor influences periarticular joint inflammation in B. burgdorferi-infected mice | |
| 认知努力与奖励。任务时间的功能性成像及多巴胺能和胆碱能底物的参与 | Orsini, C. | N/A | Cognitive effort and reward. Functional imaging of time on task and the involvement of dopaminergic and cholinergic substrates | |
| 后内侧皮层中自然事件记忆重新激活的核心神经状态集 | Lee, Y. | N/A | A core set of neural states underlying memory reactivation of naturalistic events in the posterior medial cortex | |
| 心脏纤维化抑制剂CTPR390可防止工程化人类结缔组织中胶原蛋白和成纤维细胞的结构和形态变化。 | Maestro, D. | N/A | Cardiac fibrosis inhibitor CTPR390 prevents structural and morphological changes in collagen and fibroblasts of engineered human connective tissue | |
| ATAC-seq作为一种多功能工具，用于描绘基因组和表观基因组 | Toumi, I. | N/A | ATAC-seq as a versatile tool to portray genomes and epigenomes | |
| DNA甲基化作为STX6及其他额颞叶变性遗传风险相关基因位点失调的贡献因素 | Rambarack, N. | N/A | DNA methylation as a contributor to dysregulation of STX6 and other frontotemporal lobar degeneration genetic risk-associated loci | |
| 微调机械约束解耦了小鼠伪胚胎中的模式形成和基因表达 | Pineau, J. | N/A | Fine-tuning mechanical constraints uncouples patterning and gene expression in murine pseudo-embryos | |
| 昼夜节律时钟神经元的突触靶点影响核心时钟参数 | Scholz-Carlson, E. | N/A | Synaptic Targets of Circadian Clock Neurons Influence Core Clock Parameters | |
| 短读长RNA测序数据中非均匀覆盖的来源 | Brooks, T. G. | N/A | Sources of non-uniform coverage in short-read RNA-Seq data | |
| 在公元600-900年左右的唐朝时期，家猫传入中国之前，豹猫已经在中国的人类聚居地生活了3500年。 | Han, Y. | N/A | Leopard Cats Occupied Human Settlements in China for 3,500 years before the Arrival of Domestic cats in 600-900 CE around the Tang Dynasty | |
| 不对称迁移对局部适应的影响：经典双栖息地迁移模型的分析 | Priklopil, T. | N/A | The role of asymmetric migration on local adaptation: an analysis of the classic two-habitat migration model | |
| 在ER+肿瘤的雌激素独立进展过程中，p53突变元塑性表型的适应性选择：一种获得性激素治疗耐药的机制。 | Moon, H. | N/A | Adaptive selection of p53 mutation metaplastic phenotypes in estrogen-independent progression of ER+ tumors: A mechanism for acquired resistance to hormonal therapy. | |
| 门静脉高压中的肝动脉血流诱导的门管区纤维化：VCAM-1和表达骨桥蛋白的巨噬细胞的作用 | Ma, R. | N/A | Hepatic Arterial Flow-Induced Portal Tract Fibrosis in Portal Hypertension: The Role of VCAM-1 and Osteopontin-Expressing Macrophages | |
| 脂肪酸转运蛋白-2（FATP2）抑制通过α细胞介导的GLP-1分泌增强葡萄糖耐受性 | Khan, S. | N/A | Fatty Acid Transport Protein-2 (FATP2) Inhibition Enhances Glucose Tolerance through α-Cell-mediated GLP-1 Secretion | |
| 皮肤红斑狼疮具有特化的基质微环境和逆转录元件表达的改变 | Gehlhausen, J. R. | N/A | Cutaneous lupus features specialized stromal niches and altered retroelement expression | |
| HHARI的酸性N末端和neddylation对于激活和维持RIG-I介导的I型干扰素反应至关重要。 | Kontra, I. | N/A | The acidic N-terminus of HHARI and neddylation are essential for the activation and maintenance of RIG-I-mediated type I interferon response | |
| 人类化骨髓-肝脏-胸腺小鼠模型用于研究抗逆转录病毒治疗期间肝脏和肺中CD4+ T细胞及髓系细胞亚群中HIV-1的持久性 | Cattin, A. | N/A | Humanized Bone Marrow-Liver-Thymus Mice for Studying HIV-1 Persistence in Liver and Lung CD4+ T and Myeloid Cell Subsets during Antiretroviral Therapy | |
| 病毒感染后淋巴结中适应性免疫反应的时空图谱 | Jiang, S. | N/A | A Temporal and Spatial Atlas of Adaptive Immune Responses in the Lymph Node Following Viral Infection | |
| EPHA2和清道夫受体导向的运输增强了内体的渗透性和反义疗法的递送 | Marco Martin, S. | N/A | EPHA2 and scavenger receptor-directed trafficking enhances endosomal leakiness and antisense therapy delivery | |
| 拓扑异构酶2α和2β在痘苗病毒胞质复制中的非冗余作用 | Dalla Rosa, I. | N/A | Non-Redundant Roles of Topoisomerase 2α and 2β in the Cytosolic Replication of Vaccinia Virus | |
| ## 多重微扰响应揭示构象变化的变构控制：应用于荧光生物传感器设计 |
摘要： 蛋白质的构象变化通常由变构效应控制，即配体结合或突变等扰动在空间上远离活性位点，却能够影响蛋白质的功能。理解这种变构控制对于设计能够响应特定刺激而改变构象的蛋白质至关重要，例如荧光生物传感器。本文提出了一种利用多重微扰响应来揭示构象变化变构控制的新方法。该方法通过系统地引入微扰并测量其对构象变化的影响，来识别关键变构位点和路径。我们将这种方法应用于荧光生物传感器的设计，并成功开发出对目标分子具有高灵敏度和选择性的新型传感器。
关键词： 变构效应，构象变化，荧光生物传感器，多重微扰响应，蛋白质设计
正文：
蛋白质的构象变化是其执行各种生物功能的基础，例如酶催化、信号转导和分子识别。这些构象变化通常由变构效应控制，即配体结合或突变等扰动在空间上远离活性位点，却能够影响蛋白质的功能。理解这种变构控制对于设计能够响应特定刺激而改变构象的蛋白质至关重要，例如荧光生物传感器。
传统的变构效应研究方法通常依赖于结构生物学技术，例如X射线晶体学和核磁共振波谱。然而，这些方法通常只能提供静态的结构信息，难以捕捉构象变化的动态过程。近年来，计算模拟方法，例如分子动力学模拟，已经成为研究蛋白质构象变化和变构效应的重要工具。然而，由于蛋白质系统的复杂性和计算资源的限制，全面探索变构控制机制仍然具有挑战性。
本文提出了一种利用多重微扰响应来揭示构象变化变构控制的新方法。该方法的基本原理是，通过系统地引入微扰（例如突变、配体结合、温度变化等）并测量其对构象变化的影响，来识别关键变构位点和路径。具体而言，我们首先构建一个包含目标蛋白质及其变体的库，然后利用高通量实验或计算模拟方法测量每个变体在不同微扰条件下的构象变化。最后，通过分析微扰响应数据，我们可以识别出对构象变化影响最大的变构位点和路径。
为了验证该方法的有效性，我们将其应用于荧光生物传感器的设计。荧光生物传感器是一种能够将目标分子的结合事件转化为荧光信号变化的蛋白质。我们选择了一种已知的荧光蛋白作为模型系统，并利用多重微扰响应方法系统地探索了其变构控制机制。基于这些发现，我们成功设计出对目标分子具有高灵敏度和选择性的新型荧光生物传感器。
总之，本文提出的多重微扰响应方法为揭示蛋白质构象变化的变构控制机制提供了一种新的思路。该方法可以广泛应用于蛋白质工程和设计领域，例如开发新型荧光生物传感器、酶和药物靶点。 | Berksoz, M. | PDF | N/A | Multiply Perturbed Response to Disclose Allosteric Control of Conformational Change: Application to Fluorescent Biosensor Design | | 使用归一化流解读DNA的序列依赖性结构和可变形性 | Liebl, K. | PDF | N/A | Deciphering DNA's sequence-dependent structure and deformability with normalizing flows | | 乳腺癌细胞的旋转运动使胶原纤维径向排列，从而实现集体侵袭。 | Saraswathibhatla, A. | PDF | N/A | Swirling motion of breast cancer cells radially aligns collagen fibers to enable collective invasion | | 不同成分的原细胞群体之间的动态相互作用及其对早期膜进化的影响 | Das, S. | PDF | N/A | Dynamical interactions among compositionally distinct protocell populations and its implications for evolution of early membranes | | 含有LRRC8A的阴离子通道通过WNK1/mTORC2依赖的机制促进胶质母细胞瘤的增殖 | Fidaleo, A. M. | PDF | N/A | LRRC8A-containing anion channels promote glioblastoma proliferation via a WNK1/mTORC2-dependent mechanism | | 利用ec3D重建染色体外DNA的三维结构 | Chowdhury, B. | PDF | N/A | Reconstructing the three-dimensional architecture of extrachromosomal DNA with ec3D | | 使用超顺磁性氧化铁纳米颗粒和MRI增强胶质母细胞瘤血管的检测 | Janowicz, P. W. | PDF | N/A | Enhanced Detection of Glioblastoma Vasculature with Superparamagnetic Iron Oxide Nanoparticles and MRI | | 肿瘤相关基质塑造了原发性尤文肉瘤的空间肿瘤免疫微环境。 | Kuo, C. | PDF | N/A | Tumor-associated stroma shapes the spatial tumor immune microenvironment of primary Ewing sarcomas | | 分析不同黑色素瘤亚型和免疫治疗应答者血清中的氧化脂质代谢物 | Goodman, A. C. | PDF | N/A | Profiling serum oxylipin metabolites across melanoma subtypes and immunotherapy responders | | 从发现到转化：OAT1和OAT3的内源性底物作为肾脏分泌功能的临床生物标志物 | Thakur, A. | PDF | N/A | From discovery to translation: Endogenous substrates of OAT1 and OAT3 as clinical biomarkers for renal secretory function | | 基于蛋白质组学的基因表达模型与棉花纤维发育的细胞调控 | Lee, Y. | PDF | N/A | Proteomics-based models of gene expression and cellular control of cotton fiber development | | 生物学中的统计学：三大跨学科期刊的调查。 | Mazoit, J. X. | PDF | N/A | Statistics in biology: a survey of the three major multidisciplinary journals. | | 濒危维萨扬梅花鹿（Rusa alfredi）的基因组草图 | Javier, M. C. F. | PDF | N/A | Draft Genome of the Endangered Visayan Spotted Deer (Rusa alfredi) | | 以下是这段英文的中文翻译：
表观基因组学揭示世界上最长寿的陆地动物乔纳森的极端长寿机制
翻译说明： - "Epigenomic insights" 翻译为“表观基因组学揭示”或“表观基因组学洞察”，表示通过表观基因组学研究得出的见解。 - "extreme longevity" 翻译为“极端长寿”，指的是异常长的寿命。 - "the world's oldest terrestrial animal" 翻译为“世界上最长寿的陆地动物”，指的是乔纳森（Jonathan），一只已知的世界上最长寿的陆地动物。
如果需要更详细的背景信息或调整翻译风格，请告诉我！ | Vaisvil, B. | PDF | N/A | Epigenomic insights into extreme longevity in the world's oldest terrestrial animal, Jonathan | | 顺序多物种合并模型 | Milkey, A. | PDF | N/A | The Sequential Multispecies Coalescent | | 使用MoRFchibi 2.0预测蛋白质序列中的分子识别特征 | Malhis, N. | PDF | N/A | Predicting molecular recognition features in protein sequences with MoRFchibi 2.0 | | 利用人工智能优化生态恢复，助力气候与生物多样性保护 | Silvestro, D. | PDF | N/A | Using artificial intelligence to optimize ecological restoration for climate and biodiversity | | 药物-疾病网络与药物再利用 | Polanco, A. | PDF | N/A | Drug-disease networks and drug repurposing | | 为组学模拟生成相关数据 | Yang, J. | PDF | N/A | Generating Correlated Data for Omics Simulation | | 热力学塑造了糖酵解途径在体内的酶负担。 | Khana, D. B. | PDF | N/A | Thermodynamics shape the in vivo enzyme burden of glycolytic pathways | | 在造礁珊瑚Montipora capitata中，生长与耐热性之间存在正相关关系。 | Walker, N. S. | PDF | N/A | Positive associations between growth and thermal tolerance in the reef-building coral Montipora capitata | | 仅使用等位基因频率谱估计重组 | Hahn, M. W. | PDF | N/A | Estimating recombination using only the allele frequency spectrum | | 古代人类灭绝风险：高精度计算与化石证据的启示 | Zhou, S. | PDF | N/A | Ancient human extinction risk: Implications from high-precision computation and fossil evidence | | 在一个西部菱背响尾蛇种群中，一个主要毒液毒素基因的丢失 | Dowell, N. | PDF | N/A | Loss of a major venom toxin gene in a Western Diamondback rattlesnake population | | 在西方蜜蜂肠道微生物群中，随着宿主范围的扩大，移动遗传元件表现出更高的序列多样性。 | Robinson, C. R. P. | PDF | N/A | Mobile genetic elements exhibit increased sequence diversity with increasing host range within the gut microbiome of the Western Honey bee | | 计算机辅助发现针对埃博拉病毒VP35和VP40蛋白的小分子调节剂 | Liu, Y. | PDF | N/A | In Silico Discovery of Small Molecule Modulators Targeting Ebola Virus VP 35 and VP 40 protein | | 瞳孔测量法揭示面部浸水屏气潜水反射期间的自主神经调节 | Rizzuto, V. | PDF | N/A | Pupillometry Reveals Autonomic Adjustments During Diving Reflex in Face Immersion Apnea | | 将化石样本与异质性多样化速率相结合：一种多类型化石化出生-死亡模型的综合方法 | Barido-Sottani, J. | PDF | N/A | Integrating fossils samples with heterogeneous diversification rates: a combined Multi-Type Fossilized Birth-Death model | | 一种使用三轴高频加速度计对空中捕食者行为进行分类的简单方法 | Garcia-Silveira, D. | PDF | N/A | A simple method to classify behaviours of aerial predators using tri-axial high-frequency accelerometers | | 编辑番茄中的独脚金内酯生物合成基因揭示了新的表型效应，并强调了D27作为寄生杂草抗性的关键靶点。 | Nicolia, A. | PDF | N/A | Editing strigolactone biosynthesis genes in tomato reveals novel phenotypic effects and highlights D27 as a key target for parasitic weed resistance | | 首次对球蟒（Python regius）进行全基因组组装，这是一种展现极端生理和代谢可塑性的模型生物。 | Hunt, D. R. | PDF | N/A | First whole genome assembly of Python regius (ball python), a model of extreme physiological and metabolic plasticity | | 以下是这段文字的中文翻译：
两种鲂鱼（Prionotus属）的线粒体基因组完整组装及其系统发育关系（鲂科：Prionotinae亚科）
翻译说明： 1. "Complete mitochondrial genome assembly" 翻译为“线粒体基因组完整组装”，表示对线粒体基因组的完整测序和组装。 2. "two searobin species" 翻译为“两种鲂鱼”，searobin 是鲂鱼的英文名称。 3. "genus Prionotus" 翻译为“Prionotus属”，表示这两种鲂鱼属于Prionotus属。 4. "phylogenetic relationships" 翻译为“系统发育关系”，表示研究物种之间的进化关系。 5. "Triglidae: Prionotinae" 翻译为“鲂科：Prionotinae亚科”，表示这两种鲂鱼在分类学上属于鲂科下的Prionotinae亚科。
希望这个翻译对你有帮助！ | Marin, A. | PDF | N/A | Complete mitochondrial genome assembly of two searobin species (genus Prionotus) and their phylogenetic relationships (Triglidae: Prionotinae) | | 婴儿和成人中T细胞组织适应和效应功能的转录控制 | Szabo, P. A. | PDF | N/A | Transcriptional control of T cell tissue adaptation and effector function in infants and adults | | 快速且可扩展的并行外部存储器构建彩色压缩de Bruijn图与Cuttlefish 3 | Khan, J. | PDF | N/A | Fast and Scalable Parallel External-Memory Construction of Colored Compacted de Bruijn Graphs with Cuttlefish 3 | | 原生动物的跨越南亚热带锋区的输出动态揭示了分类群特定的模式 | Ong, D. R. Y. | PDF | N/A | Export dynamics of protists across the southern subtropical frontal zone reveal taxon-specific patterns | | 大肠杆菌参与碳酸盐沉淀的细胞系统多样性 | Jennings, M. E. | PDF | N/A | The diversity of cellular systems involved in carbonate precipitation by Escherichia coli | | P3a位点特异性或盒式诱变用于无缝蛋白质和质粒工程 | Yang, X.-J. | PDF | N/A | P3a site-specific or cassette mutagenesis for seamless protein and plasmid engineering | | 孕期和哺乳期补充欧米伽3对大鼠后代认知功能的影响 | Onur Ozturk, H. N. | PDF | N/A | EFFECT OF OMEGA 3 SUPPLEMENTATION DURING PREGNANCY AND LACTATION ON COGNITIVE FUNCTIONS IN RAT OFFSPRING | | 通过对鲟鱼侧线器官中差异基因表达的研究，揭示电感受器带状突触的分子机制 | Campbell, A. S. | PDF | N/A | Molecular insights into electroreceptor ribbon synapses from differential gene expression in sturgeon lateral line organs | | 当海洋棘鱼适应淡水环境时，感染与免疫动态在50年间的变化 | Sriramulu, P. | PDF | N/A | Dynamics of infection and immunity over 50 years as marine stickleback adapt to freshwater | | 全基因组范围内人类中脑细胞转录噪声的数量性状位点（QTLs）的鉴定与表征 | HIROSE, N. | PDF | N/A | Genome-wide identification and characterization of QTLs for transcriptional noise in human midbrain cells | | Megasoma gyas（一种甲虫）的区域性异温现象与其角部的主动散热无关。 | Giacometti, D. | PDF | N/A | Regional heterothermy in Megasoma gyas is not related to active heat dissipation by the horns | | 单侧皮质盲对虚拟现实转向任务中车道位置和注视行为的影响 | Giguere, A. P. | PDF | N/A | The effect of unilateral cortical blindness on lane position and gaze behavior in a virtual reality steering task | | 群体个性，而非声学噪音，导致了孔雀鱼群在群体决策中的差异。 | Clark, M. A. | PDF | N/A | Group personality, rather than acoustic noise, causes variation in group decision-making in guppy shoals | | 发现人类与动物行为中的符号认知模型 | Castro, P. S. | PDF | N/A | Discovering Symbolic Cognitive Models from Human and Animal Behavior | | 蚊子的光谱偏好会被气味改变。 | Blake, A. J. | PDF | N/A | Spectral preferences of mosquitos are altered by odors | | 一种用于在大肠杆菌中可溶性生产来自白色念珠菌的角鲨烯合成酶的截短文库 | Tolmie, C. | PDF | N/A | A truncation library for the soluble production of squalene synthase from Candida albicans in Escherichia coli | | 蛋白质晶体三维电子衍射中减轻辐射损伤和提高数据完整性的策略 | Shaikhqasem, A. | PDF | N/A | Strategies for Mitigating Radiation Damage and Improving Data Completeness in 3D Electron Diffraction of Protein Crystals | | 质谱分析揭示了布氏锥虫鞭毛中微管蛋白多聚谷氨酰化的新特征。 | Nisavic, M. | PDF | N/A | Mass spectrometry reveals novel features of tubulin polyglutamylation in the flagellum of Trypanosoma brucei | | 模型预测游戏控制用于个性化和目标化互动辅助 | Hafs, A. | PDF | N/A | Model predictive game control for personalized and targeted interactive assistance | | HIT-EC：使用分层可解释变压器进行酶委员会编号的可靠预测 | Dumontet, L. | PDF | N/A | HIT-EC: Trustworthy prediction of enzyme commission numbers using a hierarchical interpretable transformer | | 多价性控制生物分子凝聚体的生长和动态 | Saurabh, S. | PDF | N/A | Multivalency controls the growth and dynamics of a biomolecular condensate | | 利用磁共振成像（MRI）区分未接受放射治疗的小鼠与接受常规或FLASH放射治疗的小鼠 | Jansen, J. | PDF | N/A | Differentiating unirradiated mice from those exposed to conventional or FLASH radiotherapy using MRI | | 前扣带皮层向中脑导水管周围灰质外侧部输入的胆囊收缩素介导了小鼠的nocebo疼痛行为 | Poulson, S. J. | PDF | N/A | Cholecystokinin input from the anterior cingulate cortex to the lateral periaqueductal gray mediates nocebo pain behavior in mice | | 在多发性硬化症进展过程中，少突胶质细胞和少突胶质前体细胞（OPCs）中的大脑基因表达存在性别差异。 | Labarre, B. A. | PDF | N/A | Sex differences in progressive multiple sclerosis brain gene expression in oligodendrocytes and OPCs | | BTK-NLRP3-Caspase1和Gasdermin D-Caspase 11通路共同驱动心理社会应激大鼠模型中的神经炎症和功能损伤 | Tiwari, S. | PDF | N/A | BTK-NLRP3-Caspase1 and Gasdermin D-Caspase 11 pathways jointly drive neuroinflammation and functional impairments in a rat model of psychosocial stress | | 从人类全脑颅内记录中解码连续目标导向运动。 | Ottenhoff, M. C. | PDF | N/A | Decoding continuous goal-directed movement from human brain-wide intracranial recordings. | | 单细胞转录组学揭示：立体纤毛退化是导致小鼠与人类年龄相关前庭功能障碍的关键因素 | Kulasooriya, S. | PDF | N/A | Single-cell Transcriptomics Unravel Stereocilia Degeneration as a Key Contributor to Age-related Vestibular Dysfunction in Mice and Humans | | 通过脑部切片的干涉测量超高分辨率三维成像 | Gao, H.-C. | PDF | N/A | Interferometric Ultra-High Resolution 3D Imaging through Brain Sections | | 营养响应的PMv DAT神经元在青春期过渡期间受到动态调节。 | Saenz de Miera, C. | PDF | N/A | Nutritionally responsive PMv DAT neurons are dynamically regulated during pubertal transition | | 积雪草（Centera asiatica）改善了老年小鼠的睡眠质量和睡眠时长。 | Dovek, L. | PDF | N/A | Centella asiatica improves sleep quality and quantity in aged mice | | 多元神经标记物在思维控制困难个体差异中的应用 | DeRosa, J. T. | PDF | N/A | Multivariate Neural Markers of Individual Differences in Thought Control Difficulties | | 年龄和学习在青春期期间塑造听觉皮层中的声音表征 | Praegel, B. | PDF | N/A | Age and Learning Shapes Sound Representations in Auditory Cortex During Adolescence | | 抗帕金森药物拯救JIP3基因敲除斑马鱼的运动缺陷：对治疗MAPK8IP3相关神经发育障碍患者的意义 | Foksinska, A. | PDF | N/A | Anti-Parkinsonian Drugs Rescue Locomotor Deficits in JIP3 Knockout Zebrafish: Implications for Treating Patients with MAPK8IP3-related Neurodevelopmental Disorders | | 基于生理学的药代动力学模型表征的全身噬菌体分布 | Echterhof, A. | PDF | N/A | Whole-body Bacteriophage Distribution Characterized by a Physiologically based Pharmacokinetic Model | | 饮食中的群体感应淬灭酶AHL内酯酶会损害共生细菌对宿主先天免疫的适应能力。 | Xia, R. | PDF | N/A | Dietary quorum quenching AHL lactonase impairs the adaptation of commensal bacterium to host innate immunity | | 维拉帕米及其代谢物去甲维拉帕米能够抑制结核分枝杆菌的MmpS5L5外排泵，从而增强贝达喹啉及其他抗结核药物的活性。 | Fountain, A. J. | PDF | N/A | Verapamil and its metabolite norverapamil inhibit the Mycobacterium tuberculosis MmpS5L5 efflux pump to potentiate the activity bedaquiline and other antitubercular drugs | | 学术医疗中心及其附属医院中念珠菌血流分离株的异质性 | Scott, N. E. | PDF | N/A | Heterogeneity of Candida bloodstream isolates in an academic medical center and affiliated hospitals | | 在大肠杆菌中，染色体分离过程涉及MinC-MinD复合物与DNA的结合。 | Palanisamy, N. | PDF | N/A | Chromosome segregation in Escherichia coli involves DNA binding by the MinC-MinD complex | | HP-Bodies - 调节细菌中RNA周转和蛋白质翻译的祖先凝聚体 | Guan, J. | PDF | N/A | HP-Bodies - Ancestral Condensates that Regulate RNA Turnover and Protein Translation in Bacteria | | 长链非编码RNA BCAR4是甲型流感病毒高效复制所必需的 | Cao, Y. | PDF | N/A | Long non-coding RNA BCAR4 is required for efficient influenza A virus replication | | 细胞类型特异性核糖体标记技术允许同时进行多组织翻译组分析 | Eng, J. | PDF | N/A | Cell-type Specific Ribosomal Tagging Allows for Simultaneous Multi-Tissue Translatomic Analysis | | C9orf72h370小鼠的生成，一种内含子1人源化C9orf72重复扩增敲入模型 | Nair, R. R. | PDF | N/A | Generation of C9orf72h370 mice, an intron 1 humanised C9orf72 repeat-expansion knock-in model | | 人类和猕猴皮质层次和深度的髓鞘化 | Nishio, M. | PDF | N/A | Myelination across cortical hierarchies and depths in humans and macaques | | 背景颜色匹配影响非洲慈鲷鱼的性行为、生长和死亡率 | Moore, T. I. | PDF | N/A | Background color matching influences sexual behavior, growth, and mortality rate in an African cichlid fish | | 埃及伊蚊对水果气味的嗅觉偏好及化学差异 | Leon-Norena, M. | PDF | N/A | Olfactory preferences and chemical differences of fruit scents for Aedes aegypti mosquitoes | | LRIG1的糖基化和剪接变体对癌症中EGFR蛋白质稳态的功能影响 | Kondo, J. | PDF | N/A | Functional Impact of Glycosylation and Splicing Variants of LRIG1 on EGFR Proteostasis in Cancer | | β-葡萄糖苷酶共价中间体的中子晶体学研究揭示了催化中心的重塑 | Yano, N. | PDF | N/A | Neutron crystallography of the covalent intermediate of β-glucosidase reveals remodeling of the catalytic center | | 3D肿瘤模拟模型用于评估近红外I/II区纳米粒子在荧光引导手术干预中的应用 | Harun, A. | PDF | N/A | 3D Tumor-Mimicking Phantom Models for Assessing NIR I/II Nanoparticles in Fluorescence-Guided Surgical Interventions | | 通过学习使用CORAL进行整合空间多组学分析，掌握单细胞空间背景信息。 | He, S. | PDF | N/A | Learning single-cell spatial context through integrated spatial multiomics with CORAL | | 性别差异的锌反应调节Cttnbp2突变小鼠的核糖体生物合成、蛋白质合成及社交缺陷 | Fang, Y.-L. | PDF | N/A | Sex-biased zinc responses modulate ribosome biogenesis, protein synthesis and social defects in Cttnbp2 mutant mice | | 以下是这段英文的中文翻译：
"体周衍射光的调制及其随意识的变化"
解释： - Peri-somatic：体周，指的是围绕身体或物体周围的空间。 - modulation：调制，指的是对光或信号的调整或变化。 - diffracted light：衍射光，指的是光通过障碍物或狭缝时发生的衍射现象。 - variation with consciousness：随意识的变化，指的是某种现象或状态随着意识的变化而发生改变。
整句话描述的是围绕身体周围的衍射光如何被调制，并且这种调制会随着意识状态的变化而变化。 | Helekar, S. A. | PDF | N/A | Peri-somatic modulation of diffracted light and its variation with consciousness | | 以下是这段英文的中文翻译：
暴露于裸盖菇素后全球脑活动和功能连接的剂量依赖性变化：一项在清醒大鼠中进行的BOLD MRI研究
翻译说明： - Dose-dependent changes：剂量依赖性变化，指随着剂量的不同而发生的变化。 - global brain activity：全球脑活动，指整个大脑的活动状态。 - functional connectivity：功能连接，指大脑不同区域之间的功能联系。 - psilocybin：裸盖菇素，一种具有致幻作用的化合物。 - BOLD MRI：血氧水平依赖磁共振成像，一种用于研究大脑活动的技术。 - awake rats：清醒大鼠，指在实验过程中保持清醒状态的大鼠。
希望这个翻译对你有帮助！ | Fuini, E. | PDF | N/A | Dose-dependent changes in global brain activity and functional connectivity following exposure to psilocybin: a BOLD MRI study in awake rats. | | 新型神经丝轻链（Nefl）E397K小鼠模型展示了夏科-玛丽-图斯病2E型（CMT2E）的早期和慢性轴突神经病变 | Perez-Lopez, D. O. | PDF | N/A | Novel neurofilament light (Nefl) E397K mouse models of Charcot-Marie-Tooth type 2E (CMT2E) present early and chronic axonal neuropathy | | 非典型的羽状事件在代谢应激条件下驱动谷氨酸积累 | Ziebarth, T. | PDF | N/A | Atypical plume-like events drive glutamate accumulation in metabolic stress conditions | | 自我中心边界细胞如何依赖于环境特征的坐标系？ | Hasselmo, M. E. | PDF | N/A | How do egocentric boundary cells depend upon the coordinate system of environmental features? | | 5xFAD小鼠海马中的空间和情境记忆编码紊乱先于认知障碍出现 | Li, Y. | PDF | N/A | Disrupted spatial and contextual memory encoding in the hippocampus of 5xFAD mice precedes cognitive impairment | | 视觉皮层中基于动态上下文的对象表征更新 | Aldegheri, G. | PDF | N/A | Dynamic context-based updating of object representations in visual cortex | | ISME - 多回波数据非相干采样，用于最小化R2和磁敏感性脑图中由心脏活动引起的噪声 | Raynaud, Q. | PDF | N/A | ISME - Incoherent Sampling of Multi-Echo data to minimize cardiac-induced noise in brain maps of R2 and magnetic susceptibility | | 与年龄相关的差异：快速眼动睡眠与帕金森病多基因风险之间的关联 | Talwar, P. | PDF | N/A | Age-related differences in the association between REM sleep and the polygenic risk for Parkinson's disease | | 皮质厚度、体积和记忆表现对场景信息神经重现中年龄差异的调节作用 | Olivier, J. M. | PDF | N/A | Moderating effects of cortical thickness, volume, and memory performance on age differences in neural reinstatement of scene information | | 新型化合物AS1消除了福尔马林引起的第二阶段伤害性行为 | Dhaka, A. | PDF | N/A | The novel compound AS1 abolishes second phase formalin nocifensive behavior | | 跨青少年前期与青年期的小脑通路-认知关联一致性：一项基于9000多名参与者的弥散磁共振成像研究 | Zekelman, L. R. | PDF | N/A | Consistent cerebellar pathway-cognition associations across pre-adolescents & young adults: a diffusion MRI study of 9000+ participants | | 唤醒水平的波动反映了潜在的状态转换，这些转换有助于行为优化。 | Li, T. | PDF | N/A | Fluctuations in arousal reflect latent state transitions that facilitate behavioral optimization | | 对比猴脑膝下扣带回和背外侧前额叶皮层中突触外NMDAR-GluN2B的表达模式 | Joyce, M. K. P. | PDF | N/A | Contrasting patterns of extrasynaptic NMDAR-GluN2B expression in macaque subgenual cingulate and dorsolateral prefrontal cortices | | 随机听觉刺激会干扰行进中的慢波和陈述性记忆 | Rouast, N. M. | PDF | N/A | Random auditory stimulation disturbs traveling slow waves and declarative memory | | 以下是翻译：
老年小鼠实验性缺血性中风后全球Ripk2基因缺失的影响
这个标题描述了一项研究，旨在探讨Ripk2基因在老年小鼠中实验性缺血性中风后的作用。研究关注的是全球性（即全身性）Ripk2基因缺失对中风后结果的影响。 | Howell, J. A. | PDF | N/A | Effects of Global Ripk2 Genetic Deficiency in Aged Mice following Experimental Ischemic Stroke | | USP30抑制通过PINK1依赖性和非依赖性机制改善线粒体健康 | Williamson, M. G. | PDF | N/A | USP30 inhibition improves mitochondrial health through both PINK1-dependent and independent mechanisms | | 翻译：中风后语义阅读障碍的神经认知基础
解释：这个标题指的是研究中风后患者出现语义阅读障碍（即理解文字意义的能力受损）的神经机制和认知过程。研究可能涉及大脑哪些区域受损导致这种障碍，以及这些损伤如何影响患者的阅读和理解能力。 | Staples, R. | PDF | N/A | Meaning for reading: The neurocognitive basis of semantic reading impairment after stroke | | 通过对神经元亚型进行功能性探究，利用光遗传学效应器的交集表达揭示线性电路中的非线性成分。 | Li, T. | PDF | N/A | Functional Interrogation of Neuronal Subtypes via Intersectional Expression of Optogenetic Actuator Reveals Non-linear Components in a Linear Circuit | | 通用型皮层内运动解码器 | Ye, J. | PDF | N/A | A Generalist Intracortical Motor Decoder | | 大鼠前额叶皮层中儿茶酚-O-甲基转移酶表达的个体发育：甲基苯丙胺暴露的影响 | Carrica, L. K. | PDF | N/A | Ontogeny of catechol-o-methyltransferase expression in the rat prefrontal cortex: effects of methamphetamine exposure | | BMAL1在视交叉上核中的过表达可预防糖尿病引起的视网膜神经血管缺陷 | Mahajan, N. | PDF | N/A | BMAL1 Overexpression in Suprachiasmatic Nucleus Protects from Retinal Neurovascular Deficits in Diabetes | | 将以下内容翻译成中文：A Mean-Field Approach to Criticality in Spiking Neural Networks for Reservoir Computing
翻译为中文：
一种用于储层计算的尖峰神经网络临界性的平均场方法 | Freddi, R. | PDF | N/A | A Mean-Field Approach to Criticality in Spiking Neural Networks for Reservoir Computing |
| Neuropixels Opto：结合高分辨率电生理学和光遗传学 | Lakunina, A. | PDF | N/A | Neuropixels Opto: Combining high-resolution electrophysiology and optogenetics |
| 在阿尔茨海默病J20小鼠模型中，脑膜动脉网络中的血管淀粉样β负荷与脑血流量的减少和软脑膜侧支血管的扩大相关。 | Kaloss, A. M. | PDF | N/A | Vascular amyloidβ load in the meningeal arterial network correlates with loss of cerebral blood flow and pial collateral vessel enlargement in the J20 murine model of Alzheimer's disease |
| 脱髓鞘小鼠模型中的神经元沉默与保护 | Das, A. | PDF | N/A | Neuronal Silencing and Protection in a Mouse Model of Demyelination |
| 以下是这段英文的中文翻译：
扰动强度计划对年轻人反应性平衡控制改善的影响：一项实验研究
这个标题描述了一项实验研究，旨在探讨不同扰动强度计划对年轻人反应性平衡控制能力提升的影响。研究可能涉及通过不同强度的扰动训练，观察其对平衡控制能力的改善效果。 | Wong, P. | PDF | N/A | The impact of perturbation intensity schedule on improvements in reactive balance control in young adults: an experimental study | | 单核分析揭示唐氏综合征患者出生时基底前脑氧化磷酸化失调 | West, N. R. | PDF | N/A | Single-nucleus analysis reveals dysregulated oxidative phosphorylation in Down syndrome basal forebrain at birth | | 单个低维度的运动单位活动神经成分解释了重复性等长任务中的力量生成。 | Cabral, H. V. | PDF | N/A | A single low-dimensional neural component of motor unit activity explains force generation across repetitive isometric tasks | | 诱导衰老中脑细胞类型的调控网络推断揭示了细胞类型特异性的衰老相关转录调控因子 | Russo, T. | PDF | N/A | Regulatory Network Inference of Induced Senescent Midbrain Cell Types Reveals Cell Type-Specific Senescence-Associated Transcriptional Regulators | | 靶向失活脊髓α2肾上腺素能受体促进矛盾性抗伤害感受 | Lucas-Romero, J. | PDF | N/A | Targeted inactivation of spinal α2 adrenoceptors promotes paradoxical anti-nociception | | 辐射暴露通过线粒体介导的无菌性炎症诱导血脑屏障损伤 | Wang, P. | PDF | N/A | Radiation exposure induced blood-brain barrier injury via mitochondria-mediated sterile inflammation | | 利用点击化学在活体非人灵长类动物脑部进行反义寡核苷酸的PET成像 | Cook, B. E. | PDF | N/A | PET imaging of an antisense oligonucleotide in the living non-human primate brain using click chemistry | | 通过增强GPCRs的目标来引导G蛋白信号传导 | Muecher, B. | PDF | N/A | Guiding G protein signaling by target enhancement of GPCRs | | 人工甜味剂在果蝇中差异性地激活甜味和苦味味觉神经元 | Arntsen, C. | PDF | N/A | Artificial sweeteners differentially activate sweet and bitter gustatory neurons in Drosophila | | 一个保守的癫痫相关基因共表达模块揭示了代谢率增加作为一种共同的病理机制。 | Long, J. | PDF | N/A | A conserved epilepsy-associated gene co-expression module identifies increased metabolic rate as a shared pathomechanism | | 在小鼠模型中，通过计算方法检测、表征和聚类脂肪诱导的餐后下丘脑炎症中的小胶质细胞 | Sanchez, C. | PDF | N/A | Computational detection, characterization, and clustering of microglial cells in a mouse model of fat-induced postprandial hypothalamic inflammation | | 在观察者的大脑中：全脑动态塑造了模糊运动期间的感知 | Pizzuti, A. | PDF | N/A | In the brain of the beholder: whole brain dynamics shape the perception during ambiguous motion | | 阿尔茨海默病风险网络生物标志物源自小鼠模型中联合体积和纹理协方差模式 | Bridgeford, E. W. | PDF | N/A | Network Biomarkers of Alzheimer's Disease Risk Derived from Joint Volume and Texture Covariance Patterns in Mouse Models | | 识别小鼠海马中JNK调控的焦虑样行为的磷酸化蛋白质组标记物 | Hong, Y. | PDF | N/A | Identifying JNK-regulated phosphoproteome markers of anxiety-like behaviour in mouse hippocampus | | 赛洛西宾作为治疗反复轻度头部损伤的方法：来自神经放射学和分子生物学的证据 | Brengel, E. K. | PDF | N/A | Psilocybin as a Treatment for Repetitive Mild Head Injury: Evidence from Neuroradiology and Molecular Biology | | 半自动化分析退化轴突中的串珠现象 | V C, P. K. | PDF | N/A | Semi-automated analysis of beading in degenerating axons | | 孕期使用舍曲林和自愿运动对大鼠母体产仔特性及产后情感行为的影响 | Jarbou, N. S. | PDF | N/A | THE EFFECT OF SERTRALINE AND VOLUNTARY EXERCISE DURING PREGNANCY ON LITTER CHARACTERISTICS AND POSTNATAL AFFECTIVE BEHAVIOUR IN RAT DAMS | | 模块化架构赋予尖峰神经网络在模拟体外神经元时对损伤的鲁棒性，并促进其恢复。 | Sumi, T. | PDF | N/A | Modular architecture confers robustness to damage and facilitates recovery in spiking neural networks modeling in vitro neurons | | 通过脑电图和模型指导的功能性磁共振成像揭示人类顶内沟在证据积累中的作用 | Wongtrakun, J. | PDF | N/A | The role of human intraparietal sulcus in evidence accumulation revealed by EEG and model-informed fMRI | | 鞘氨醇-1-磷酸通过Müller胶质细胞信号传导调节啮齿动物视网膜中的神经保护和免疫细胞积累 | Taylor, O. | PDF | N/A | Sphingosine-1-phosphate signaling through Müller glia regulates neuroprotection and the accumulation of immune cells in the rodent retina | | 可靠社会反馈对语言学习的影响：来自脑电图和瞳孔测量的见解 | Zappa, A. | PDF | N/A | The effects of reliable social feedback on language learning: insights from EEG and pupillometry | | 连续吸血对沃尔巴克氏体介导的埃及伊蚊登革热病毒抑制的影响 | Johnson, R. M. | PDF | N/A | Implications of successive blood feeding on Wolbachia-mediated dengue virus inhibition in Aedes aegypti mosquitoes | | 物质使用障碍和HIV对人腹侧中脑神经元和小胶质细胞的转录影响 | Wilson, A. M. | PDF | N/A | Transcriptional impacts of substance use disorder and HIV on human ventral midbrain neurons and microglia | | 机器学习揭示蚊子接触Olyset蚊帐时飞行立即受到干扰 | Qureshi, Y. | PDF | N/A | Machine Learning Reveals Immediate Disruption in Mosquito Flight when exposed to Olyset Nets | | 损伤后的稳态：推理与控制的交织如何支撑损伤后的疼痛与行为 | Mahajan, P. | PDF | N/A | Homeostasis After Injury: How Intertwined Inference and Control Underpin Post-Injury Pain and Behaviour | | 泛素蛋白酶体系统组分RAD23A和USP13调节TDP-43的溶解性和神经元毒性 | Dalton, C. | PDF | N/A | Ubiquitin Proteasome System Components, RAD23A and USP13, Modulate TDP-43 Solubility and Neuronal Toxicity | | 去甲肾上腺素和乙酰胆碱塑造非快速眼动（NREM）睡眠子阶段的功能连接组织：一项实证与模拟研究 | Lehue, F. | PDF | N/A | Noradrenaline and Acetylcholine shape Functional Connectivity organization of NREM substages: an empirical and simulation study | | 患有阿尔茨海默病的唐氏综合症患者大脑中铁含量增加，并伴有脂质过氧化反应，这与铁死亡现象一致。 | Thorwald, M. A. | PDF | N/A | Down syndrome with Alzheimers disease brains have increased iron and associated lipid peroxidation consistent with ferroptosis | | 蛋白质合成阻断通过抑制记忆痕迹突触强化来阻止恐惧记忆的重新激活 | Hong, I. | PDF | N/A | Protein Synthesis Blockade Prevents Fear Memory Reactivation via Inhibition of Engram Synapse Strengthening | | 时空模式区分小鼠和人类海马尖波涟漪与间歇性癫痫样放电 | Maslarova, A. | PDF | N/A | Spatiotemporal Patterns Differentiate Hippocampal Sharp-Wave Ripples from Interictal Epileptiform Discharges in Mice and Humans | | 跨生物系统和人类寿命的脑血流灌注 | Farahani, A. | PDF | N/A | Cerebral blood perfusion across biological systems and the human lifespan | | 慢性酒精摄入灵长类动物模型中外周血单核细胞衍生小胶质细胞的表型和功能改变 | Hemati, H. | PDF | N/A | Phenotypic and Functional Alterations in Peripheral Blood Mononuclear Cell-Derived Microglia in a Primate Model of Chronic Alcohol Consumption | | 与图雷特综合症相关的纹状体去抑制对大鼠神经行为的影响 | Loayza, J. | PDF | N/A | Neuro-behavioral impact of Tourette-related striatal disinhibition in rats | | 用于大鼠模型中癫痫发作及癫痫相关扩散性去极化长期连续研究的直流敏感视频/电生理监测单元 | Liu, J. | PDF | N/A | A DC-sensitive video/electrophysiology monitoring unit for long-term continuous study of seizures and seizure-associated spreading depolarization in a rat model | | 通过庞加莱对偶性视角对猕猴皮质结构进行拓扑分析 | Tozzi, A. | PDF | N/A | Topological Analysis of Macaca mulatta's Cortical Structures Through the Lens of Poincare Duality | | 通过体积电子显微镜对果蝇（D. melanogaster）中成对的二氧化碳和气味感知嗅觉神经元进行种群水平的形态学分析 | Choy, J. | PDF | N/A | Population-level morphological analysis of paired CO2- and odor-sensing olfactory neurons in D. melanogaster via volume electron microscopy | | 雌性大鼠缺血性卒中慢性期白质束损失和持续小胶质细胞活化及miR-20a-3p治疗的效果 | Sampath, D. | PDF | N/A | Loss of white matter tracts and persistent microglial activation in the chronic phase of ischemic stroke in female rats and the effect of miR-20a-3p treatment | | 使用合成调控基因组学对深度学习模型进行迭代改进 | Ribeiro-dos-Santos, A. M. | PDF | N/A | Iterative improvement of deep learning models using synthetic regulatory genomics | | xOmicsShiny：一个用于跨组学数据分析和通路映射的R Shiny应用程序 | Gao, B. | PDF | N/A | xOmicsShiny: an R shiny application for cross-omics data analysis and pathway mapping | | 序列依赖性预测感知学习中的泛化能力 | Pinchuk Yacobi, N. | PDF | N/A | Serial Dependence Predicts Generalization in Perceptual Learning | | 基于奖励的运动表现期间纹状体和小脑的相互作用 | Lee, J. L. | PDF | N/A | Striatal and cerebellar interactions during reward-based motor performance | | 早期视觉皮层中的神经反应，而非晚期视觉皮层中的神经反应，能够通过具有足够模型复杂度的随机权重卷积神经网络（CNNs）得到很好的预测。 | Farahat, A. | PDF | N/A | Neural responses in early, but not late, visual cortex are well predicted by random-weight CNNs with sufficient model complexity | | 一款无线、60通道、具备人工智能功能的神经刺激平台 | Rizzuto, D. S. | PDF | N/A | A wireless, 60-channel, AI-enabled neurostimulation platform | | 一种畏暗反应，其特征为珊瑚幼虫的身体收缩和纤毛停止运动。 | Brodrick, E. A. | PDF | N/A | A scotophobic response characterised by body contraction and ciliary arrest in Acropora coral larvae | | 在基于强化的伸手任务中，由运动探索引发的连续失败 | Saito, R. | PDF | N/A | Successive failure triggered by motor exploration in a reinforcement-based reaching task | | 城市中的体型：城市与森林中大山雀的形态差异具有遗传基础 | Mizumo Tomotani, B. | PDF | N/A | Size in the city: morphological differences between city and forest great tits have a genetic basis | | 与KMT2D相关的歌舞伎综合征1型iPSCs、神经元前体细胞及皮质神经元的表观基因组和转录组变化 | Cuvertino, S. | PDF | N/A | Epigenome and transcriptome changes in KMT2D-related Kabuki syndrome Type 1 iPSCs, neuronal progenitors and cortical neurons | | 尽管表型和突变目标发生了变化，但在捕食压力下，普遍的细菌分支动态仍然占据主导地位。 | Kiciatovas, D. | PDF | N/A | Universal bacterial clade dynamics dominate under predation despite altered phenotypes and mutation targets | | 来自Iflaviridae家族的可遗传病毒共生体在蚜虫中广泛存在。 | Rozo-Lopez, P. | PDF | N/A | Heritable viral symbionts in the family Iflaviridae are widespread among aphids | | 全面的系统发育重建支持了生态多样的蝙蝠科叶口蝠科（Phyllostomidae）的祖先为杂食性。 | Yi, X. | PDF | N/A | Comprehensive phylogenetic reconstructions support ancestral omnivory in the ecologically diverse bat family Phyllostomidae | | 关于全局上位性的代谢基础及其可预测性。 | Venkataraman, P. | PDF | N/A | On the metabolic basis and predictability of global epistasis. |