BioRxiv 2025-02-17 Papers
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| MOSim：批量与单细胞多层调控网络模拟器 | Monzo, C. | N/A | MOSim: bulk and single-cell multi-layer regulatory network simulator | |
| 学习后海马体-纹状体活动的重放受到奖励预测误差的影响。 | Roscow, E. L. | N/A | Post-learning replay of hippocampal-striatal activity is biased by reward-prediction errors | |
| 在非洲爪蟾早期胚胎发育过程中蛋白质组和磷酸化蛋白质组的变化 | Van Itallie, E. | N/A | Transitions in the proteome and phospho-proteome during early embryonic development in Xenopus | |
| 隐藏的GPCR结构转变通过多行走者监督分子动力学（mwSuMD）方法进行研究 | Deganutti, G. | N/A | Hidden GPCR structural transitions addressed by multiple walker supervised molecular dynamics (mwSuMD) | |
| 齿鲸寿命的贝叶斯推断 | Ellis, S. | N/A | Bayesian inference of toothed whale lifespans | |
| 利用人类干细胞模型解析猴痘病毒（MPXV）的神经趋向性和宿主抗病毒信号传导 | Bauer, L. | N/A | Dissecting MPXV neurotropism and host antiviral signaling using human stem cell-based models | |
| Stumpy形式是布鲁氏锥虫的主要传播形式。 | Ngoune, J. M. T. | N/A | Stumpy forms are the predominant transmissible forms of Trypanosoma brucei. | |
| 通过基于试验的测定揭示的帕金森病果蝇模型中对威胁刺激的反应性改变 | Kajtor, M. | N/A | Altered reactivity to threatening stimuli in Drosophila models of Parkinson's disease, revealed by a trial-based assay | |
| 稳定性指标在不同数据质量下表现稳健，但对社区规模较为敏感。 | O'Brien, D. A. | N/A | Stability metrics are robust across data qualities but sensitive to community size. | |
| CellSAM: 细胞分割的基础模型 | Israel, U. | N/A | CellSAM: A Foundation Model for Cell Segmentation | |
| 比较六种稳定集合种群动态的方法及其对普查噪声的鲁棒性 | Singh, A. | N/A | Comparison of six methods for stabilizing metapopulation dynamics and for their robustness against census noise | |
| 对SOD1-G93A小鼠肌肉生物标志物进行综合分析，以全面评估ALS进展 | Gomez-Galvez, P. J. | N/A | Computational analysis of SOD1-G93A mouse muscle biomarkers for comprehensive assessment of ALS progression | |
| 布朗运动下利用完整祖先重组图进行空间推断的承诺与挑战 | Deraje, P. | N/A | The promise and challenge of spatial inference with the full ancestral recombination graph underBrownian motion | |
| 开发D-box肽以抑制后期促进复合物/环体（Anaphase Promoting Complex/Cyclosome） | Eapen, R. | N/A | Development of D-box peptides to inhibit the Anaphase Promoting Complex/Cyclosome | |
| miRTarDS：利用Sentence-BERT从预测数据库中高精度筛选蛋白质水平的微RNA靶标相互作用 | Chen, B. | N/A | miRTarDS: High-Accuracy Refining Protein-level MicroRNA Target Interactions from Prediction Databases Using Sentence-BERT | |
| 自我报告睡眠质量的皮层下相关因素 | Monti, M. M. | N/A | The subcortical correlates of self-reported sleep quality | |
| 细胞在资源限制下的扩张与分裂：一种模拟水果生长动态的新框架 | Miele, L. | N/A | Cell expansion-division under resource limitation: a novel framework for modeling fruit growth dynamics | |
| 双语语言处理依赖于由每种语言调节的共享语义表征。 | Chen, C. | N/A | Bilingual language processing relies on shared semantic representations that are modulated by each language | |
| PP2A-B56调控Mid1蛋白水平以确保裂殖酵母的细胞分裂正常进行。 | Chrupcala, M. L. | N/A | PP2A-B56 regulates Mid1 protein levels for proper cytokinesis in fission yeast | |
| 质膜折叠使得生长中的哺乳动物细胞能够保持恒定的表面积与体积比。 | Wu, W. | N/A | Plasma membrane folding enables constant surface area-to-volume ratio in growing mammalian cells | |
| 活动依赖性突触消除需要caspase-3的激活 | Yu, Z. | N/A | Activity-dependent synapse elimination requires caspase-3 activation | |
| 小鼠内侧背丘脑中与味觉相关信号的神经处理。 | Odegaard, K. E. | N/A | Neural Processing of Taste-related Signals in the Mediodorsal Thalamus of Mice. | |
| 通过与体外模型的定量比较，伪造内皮细胞网络形成的计算模型 | Vergroesen, T. M. | N/A | Falsifying computational models of endothelial cell network formation through quantitative comparison with in vitro models | |
| 四甲基罗丹明的自淬灭是一种在15至25埃尺度上探测构象变化的探针。 | Girvan, P. | N/A | Tetramethylrhodamine self-quenching is a probe of conformational change on the scale of 15 - 25 Angstroms | |
| 南极阿德利企鹅幼崽存活率下降 | Barracho, T. | N/A | Declining juvenile survival of Adelie penguins in Antarctica | |
| 斑胸草雀的突变和重组参数与哺乳动物相似。 | Prentout, D. | N/A | Mutation and recombination parameters in zebra finch are similar to those in mammals | |
| 开发异种不育昆虫技术用于害虫控制：来自斑翅果蝇（Drosophila suzukii）的见解 | Cerasti, F. | N/A | Developing heterospecific Sterile Insect Technique for pest control: insights from the spotted wing fly Drosophila suzukii | |
| PDZ介导的底物招募是PP1-Neurabin特异性去磷酸化4E-BP1的主要决定因素。 | Fedoryshchak, R. O. | N/A | PDZ-directed substrate recruitment is the primary determinant of specific 4E-BP1dephosphorylation by PP1-Neurabin | |
| 弱而特异的化学相互作用决定了巴纳酶在不同细胞环境中的稳定性。 | Tahir, U. | N/A | Weak, specific chemical interactions dictate barnase stability in diverse cellular environments | |
| 将这段翻译成中文为： |
Trp53Y217C的致癌和致畸效应，这是一种易发炎症的小鼠模型，模拟了人类热点突变TP53Y220C。 | Jaber, S. | PDF | N/A | Oncogenic and teratogenic effects of Trp53Y217C, an inflammation-prone mouse model of the human hotspot mutant TP53Y220C | | 我们能否根据大脑特征预测睡眠健康？一项利用英国生物银行进行的大规模机器学习研究 | Raimondo, F. | PDF | N/A | Can we predict sleep health based on brain features? A large-scale machine learning study using UK Biobank | | 人类全脑睡眠节律的激活 | Wang, H. | PDF | N/A | Human Brain-Wide Activation of Sleep Rhythms | | 一项全球性的努力，旨在为预测模型设定基准，并揭示长期卒中结局中的机制多样性。 | Matsulevits, A. | PDF | N/A | A global effort to benchmark predictive models and reveal mechanistic diversity in long-term stroke outcomes | | Shc1与Frs2和Shp2合作，在FGF诱导的晶状体发育过程中募集Grb2。 | Wang, Q. | PDF | N/A | Shc1 cooperates with Frs2 and Shp2 to recruit Grb2 in FGF-induced lens development | | 鸟类因青藏高原隆起引发的亚洲季风效应而进行纵向迁徙。 | Zhang, W. | PDF | N/A | Birds migrate longitudinally in response to the resultant Asian monsoons of the Qinghai-Tibet Plateau uplift | | 评估使用扩散去噪概率模型生成的合成扩散MRI图像 | Chattopadhyay, T. | PDF | N/A | Evaluating Synthetic Diffusion MRI Maps created with Diffusion Denoising Probabilistic Models | | 在一个典型的刺胞动物-藻类共生模型中，当无性繁殖的后代在缺乏异养摄食的情况下发育时，共生关系会崩溃。 | Bedgood, S. A. | PDF | N/A | Symbiosis collapses during development of asexual offspring in the absence of heterotrophic feeding in a model cnidarian-algal symbiosis | | 一个用于多模态体内池化遗传筛选的平台揭示了肝脏功能的调控因子 | Saunders, R. A. | PDF | N/A | A platform for multimodal in vivo pooled genetic screens reveals regulators of liver function | | 一种新型的多重RNAi疗法同时靶向Hif1a和Hif2a，以对抗两种AMD模型中的视网膜退化。 | Ebner, L. J. A. | PDF | N/A | A novel multiplex RNAi therapy simultaneously targets Hif1a and Hif2a to defy retinal degeneration in two models of AMD | | 优化蛋白质-辅料相互作用在Martini 3力场中的应用 | Prass, T. M. | PDF | N/A | Optimized Protein-Excipient Interactions in the Martini 3 Force Field | | 使用大型语言模型生成抗原特异性配对链抗体序列 | Wasdin, P. T. | PDF | N/A | Generation of antigen-specific paired chain antibody sequences using large language models | | Ustilago maydis转录因子Nit2在生物营养期间调节硝酸盐的利用，并在氮限制条件下影响受感染玉米叶片中的有机氮代谢。 | Lopinski, P. L. | PDF | N/A | The Ustilago maydis transcription factor Nit2 regulates nitrate utilization during biotrophy and influences organic nitrogen metabolism in infected maize leaves under nitrogen limitation | | BICD2是一种中心粒蛋白，它控制着母-子中心粒的结合以及复制许可的过程。 | Montes-Ruiz, L. | PDF | N/A | BICD2 is a centriolar protein that controls mother-daughter centriole engagement and the licensing of duplication | | 对恒河猴免疫球蛋白基因座变异的广泛调查与功能分析 | Peres, A. | PDF | N/A | A Broad Survey and Functional Analysis of Immunoglobulin Loci Variation in Rhesus Macaques | | 使用大规模生成式变压器进行T细胞表位的库水平生成 | Ma, M. | PDF | N/A | Repertoire-level generation of T-cell epitopes with a large-scale generative transformer | | 拟南芥真菌内生菌培养滤液乙酸乙酯提取物的杀线虫和拒食活性 | Diaz-Gonzalez, S. | PDF | N/A | Nematicidal and antifeedant activity of ethyl acetate extracts from culture filtrates of Arabidopsis thaliana fungal endophytes | | 从发酵鸡肉中提取的四种乳酸菌的基因组草图揭示了抗菌化合物的生物合成基因簇 | Alam, M. | PDF | N/A | Draft genome sequences of four lactic acid bacteria from fermented chicken meat unveil biosynthetic gene clusters for antimicrobial compounds | | 胆管细胞的初级纤毛调控DNA损伤反应与修复 | Peixoto, E. | PDF | N/A | Cholangiocytes' Primary Cilia Regulate DNA Damage Response and Repair | | CTCF直接结合G-四链体结构以调节基因组拓扑结构和基因表达 | Castruita, D. S. | PDF | N/A | CTCF directly binds G-quadruplex structures to regulate genome topology and gene expression | | 从功能基因组学数据中鉴定病毒变异体 | Röckl, F. | PDF | N/A | Identification of Viral Variants from Functional Genomics Data | | 拟南芥叶片质外体中模式触发免疫的蛋白质组景观 | Chen, H.-C. | PDF | N/A | Proteomic Landscape of Pattern Triggered Immunity in the Arabidopsis Leaf Apoplast | | 通过数据和机制驱动的分布式大规模网络模型解码酵母转录调控 | Fan, X. | PDF | N/A | Decoding yeast transcriptional regulation via a data- and mechanism-driven distributed large-scale network model | | 钙通道偶联转录因子促进直接的核信号传导 | Rao, E. R. | PDF | N/A | Calcium channel-coupled transcription factors facilitate direct nuclear signaling | | 学习在传递性推理任务中解耦了快速决策的准确性和反应时间 | Silva, F. A. M. | PDF | N/A | Learning decouples accuracy and reaction time for rapid decisions in a transitive inference task | | 纳米突起扩大沿着最小阻力路径进行细胞囊管延伸，以启动转移过程。 | Yi, T. | PDF | N/A | Nanoprotrusion enlargement conducts cytocapsular tube elongation along the path of least resistance for metastasis initiation | | 沿亚北极永久冻土融化梯度的RNA病毒生态基因组学研究 | Pratama, A. A. | PDF | N/A | RNA virus ecogenomics along a subarctic permafrost thaw gradient | | 基于现场可编程门阵列的超低功耗离散傅里叶变换用于闭环神经传感 | Yang, R. | PDF | N/A | Field-Programmable Gate Array Based Ultra-Low Power Discrete Fourier Transforms for Closed-Loop Neural Sensing | | 以下是翻译：
在雪貂听觉皮层中对自然声音混合的分层编码
这个标题描述了一项研究，该研究探讨了雪貂听觉皮层如何处理和编码自然声音的混合。研究重点是分层编码，即不同层次或阶段的神经元对声音信息的逐步处理和整合。 | Landemard, A. | PDF | N/A | Hierarchical encoding of natural sounds mixtures in ferret auditory cortex | | 脂肪组织扩张和消退过程中VEGF和PDGF配体及受体蛋白表达的性别差异 | Fang, Y. | PDF | N/A | Sex Differences in VEGF and PDGF Ligand and Receptor Protein Expression during Adipose Tissue Expansion and Regression | | Mrx6蛋白结合Lon蛋白酶Pim1的N端结构域，以赋予其选择性底物特异性并调控线粒体DNA（mtDNA）的拷贝数。 | Schrott, S. | PDF | N/A | Mrx6 binds the Lon protease Pim1 N-terminal domain to confer selective substrate specificity and regulate mtDNA copy number | | Mavacamten通过稳定肌球蛋白相互作用头基序并阻止运动力的产生来抑制肌球蛋白的活性。 | McMillan, S. N. | PDF | N/A | Mavacamten inhibits myosin activity by stabilising the myosin interacting-heads motif and stalling motor force generation | | 绘制面包小麦中bZIP转录因子的二聚化特异性图谱 | Kaur, R. | PDF | N/A | Mapping the dimerization specificity of bZIP transcription factors in bread wheat | | 黑猩猩额极的空间和单核转录组图谱 | Alagöz, G. | PDF | N/A | Spatial and single-nucleus transcriptomic profile of a chimpanzee frontal pole | | 吡喹酮及其强效类似物WCDD115通过抑制二氢叶酸还原酶（DHFR）和一碳代谢来抑制NRF2。 | Chembo, J. | PDF | N/A | Pyrimethamine and a potent analogue WCDD115 inhibit NRF2 by suppressing DHFR and one-carbon metabolism | | 探索-开发决策的动态机制表明，老年人随机探索行为的减少可能涉及一种阈值机制。 | Phelps, C. E. | PDF | N/A | The dynamics of explore-exploit decisions suggest a threshold mechanism for reduced random exploration in older adults | | DNA错配修复在小鼠感觉处理中的非经典作用 | Oviedo, H. V. | PDF | N/A | Non-Canonical Role of DNA Mismatch Repair on Sensory Processing in Mice | | 3BTRON：一种血脑屏障识别网络
3BTRON（Blood-Brain Barrier Recognition Network）是一种专门设计用于识别和解析血脑屏障（Blood-Brain Barrier, BBB）相关数据的网络模型。血脑屏障是大脑中的一种重要生理结构，它能够保护大脑免受有害物质的侵害，同时也限制了药物等治疗物质进入大脑。3BTRON通过先进的算法和数据处理技术，能够高效地识别和分析与血脑屏障相关的生物标志物、药物渗透性以及其他关键信息，从而为神经科学研究、药物开发和疾病治疗提供有力支持。 | Fletcher-Lloyd, N. V. | PDF | N/A | 3BTRON: A Blood-Brain Barrier Recognition Network | | 大规模环境通过网格细胞的铺砌需要经验 | Gutierrez-Guzman, B. E. | PDF | N/A | Tiling of large-scaled environments by grid cells requires experience | | 由于卵母细胞中黏连蛋白保护错误导致的杂交雌性不育 | El Yakoubi, W. | PDF | N/A | Hybrid female sterility due to cohesin protection errors in oocytes | | MCAK/Kif2C 着丝粒活性水平调节 K-纤维稳定性。 | Wordeman, L. | PDF | N/A | MCAK/Kif2C centromeric activity level tunes K-fiber stability. | | 一种用于将诱导多能干细胞（iPSC）分化为产生皮质醇的类固醇生成细胞的病毒转导方法 | Lee-Glover, L. P. | PDF | N/A | A viral transduction approach for iPSC differentiation into cortisol-producing steroidogenic cells | | 角蛋白通过平衡扩散力与组织材料特性来协调组织的扩散。 | Naik, S. | PDF | N/A | Keratins coordinate tissue spreading by balancing spreading forces with tissue material properties | | 共同起源，不同结果：Yap和Taz缺失对雪旺细胞和嗅觉鞘细胞发育的不同影响，而不干扰GnRH-1迁移 | Taroc, E. Z. M. | PDF | N/A | Shared Lineage, Distinct Outcomes: Yap and Taz Loss Differentially Impact Schwann and Olfactory Ensheathing Cell Development Without Disrupting GnRH-1 Migration | | 大西洋蓝蟹（学名：Callinectes sapidus，Rathbun, 1896）在亚得里亚海和爱琴海沿海地区以及大西洋伊比利亚海岸的感染情况 | Schott, E. | PDF | N/A | Infections in the Atlantic Blue Crab Callinectes sapidus (Rathbun, 1896) in coastal Adriatic and Aegean sea, and Atlantic Iberian coast | | 蚊子媒介——埃及伊蚊的本地适应性，及其对预测温度和气候变化对登革热传播影响的意义。 | Dennington, N. | PDF | N/A | Local adaptation of the mosquito vector, Aedes aegypti, and implications for predicting the effects of temperature and climate change on dengue transmission. | | 最大熵网络显示，植物与丛枝菌根真菌的关联呈现反嵌套性和模块化特征。 | Ajaz, S. | PDF | N/A | Maximum entropy networks show that plant-arbuscular mycorrhizal fungal associations are anti-nested and modular | | 用于健康和疾病中双(单酰基甘油)磷酸酯分析的高效分析方法 | Dong, W. | PDF | N/A | Robust analytical methods for bis(monoacylglycero)phosphate profiling in health and disease | | Morpheus：一种基于片段的算法，用于预测蛋白质组中蛋白质的变构行为 | Subramanian, V. | PDF | N/A | Morpheus: A fragment-based algorithm to predict metamorphic behaviour in proteins across proteomes | | 错义变异分析在TRPV1 ARD中揭示了甲硫氨酸的意外功能重要性 | Wulffraat, G. C. | PDF | N/A | Missense variant analysis in the TRPV1 ARD reveals the unexpected functional significance of a methionine | | 水凝胶印迹与透明化处理的DNA-PAINT成像 | Stein, J. | PDF | N/A | DNA-PAINT imaging with hydrogel imprinting and clearing | | 使用深度学习预测大麦基因库种质地理起源对基因组-环境关联研究的影响 | Chang, C.-W. | PDF | N/A | Effects of using deep learning to predict the geographic origin of barley genebank accessions on genome-environment association studies | | 植物标本馆为获取有信息量的mRNA提供了宝贵的资源。 | Tyszka, A. S. | PDF | N/A | Herbaria provide a valuable resource for obtaining informative mRNA | | 以下是这段英文的中文翻译：
茄科植物龙葵（Solanum nigrum）和苦茄（Solanum dulcamara）基因组的组装与注释：两种对青枯病菌（Ralstonia solanacearum）具有不同敏感性的植物
翻译说明： 1. Solanum dulcamara 通常称为苦茄或欧白英。 2. Solanum nigrum 通常称为龙葵或黑茄。 3. Ralstonia solanacearum 是青枯病菌，一种常见的植物病原菌。 4. nightshades 指茄科植物。
希望这段翻译对你有帮助！ | Franco Ortega, S. | PDF | N/A | Assembly and annotation of Solanum dulcamara and Solanum nigrum plant genomes, two nightshades with different susceptibilities to Ralstonia solanacearum | | 行星尺度的海洋群落模型预测了代谢协同作用和病毒的影响 | Regimbeau, A. | PDF | N/A | Planetary-scale marine community modeling predicts metabolic synergy and viral impacts | | 合成群落作为确定生物肥料底盘生物与本地微生物群落之间相互作用的模型 | Madsen, C. S. | PDF | N/A | Synthetic communities as a model for determining interactions between a biofertilizer chassis organism and native microbial consortia | | 森林的组成与配置以及城市发展共同影响了北美温带森林中蝙蝠的活动和多样性。 | Chen, S. | PDF | N/A | Both composition and configuration of forests and urban development shape bat activity and diversity in North American temperate forests | | 墨西哥丽脂鲤在营养限制下的生殖适应 | Xia, F. | PDF | N/A | Reproductive Adaptation of Astyanax mexicanus Under Nutrient Limitation | | 一种灵活的贝叶斯方法，用于估算地层间隔及其在时间上的共现性 | Ballen, G. A. | PDF | N/A | A flexible Bayesian method for estimating stratigraphic intervals and their co-occurrence in time | | 在类似南方古猿的髋关节中的髋部稳定：形状对肌肉激活的影响 | Kramer, P. A. | PDF | N/A | Hip stabilization in an australopithecine-like hip: the influence of shape on muscle activation | | 《收割蚁（膜翅目：蚁科：窄腹蚁族）的系统基因组学揭示了其生物地理起源和多样化模式》
这篇研究通过系统基因组学的方法，探讨了收割蚁（Messor属）的生物地理起源及其多样化模式。收割蚁属于膜翅目蚁科中的窄腹蚁族（Stenammini），研究通过分析其基因组数据，揭示了该类蚂蚁的进化历史和分布规律。 | Juve, Y. | PDF | N/A | Phylogenomics of Messor harvester ants (Hymenoptera: Formicidae: Stenammini) unravels their biogeographical origin and diversification patterns | | 预测杂交适应性：倍性和复杂祖先的影响 | Schneemann, H. | PDF | N/A | Predicting Hybrid Fitness: the Effects of Ploidy and Complex Ancestry | | 栽培象腿蕉中隐性三倍体的反复进化提高了产量 | Dussert, Y. | PDF | N/A | Recurrent evolution of cryptic triploids in cultivated enset increases yield | | 在裸鳃类腹足动物中，一部分保守的吞噬基因可能被用于细胞内窃取刺胞动物的刺胞器官。 | Goodheart, J. A. | PDF | N/A | A subset of conserved phagocytic genes are likely used for the intracellular theft of cnidarian stinging organelles in nudibranch gastropods | | 生态学和性别冲突推动雌性限制颜色多态性的宏观进化动态 | Willink, B. | PDF | N/A | Ecology and sexual conflict drive the macroevolutionary dynamics of female-limited colour polymorphisms | | 系统基因组学分析揭示，盘古古菌是一类基因组缩减的阿斯加德古菌分支。 | Huang, W.-C. | PDF | N/A | Phylogenomic analyses reveal that Panguiarchaeum is a clade of genome-reduced Asgard archaea | | 将“Antero-posterior patterning in the brittle star Amphipholis squamata and the evolution of body plans across echinoderms”翻译成中文是：“脆海星Amphipholis squamata的前后轴模式及其在棘皮动物中的体轴演化”。 | Formery, L. | PDF | N/A | Antero-posterior patterning in the brittle star Amphipholis squamata and the evolution of body plans across echinoderms | | 通过选择金鱼草中的多个基因座来塑造发育梯度 | Bradley, D. | PDF | N/A | Shaping of developmental gradients through selection on multiple loci in Antirrhinum | | 母亲年龄和减数分裂重组全基因组失败与人类三倍体妊娠相关 | Picchetta, L. | PDF | N/A | Maternal age and genome-wide failure of meiotic recombination are associated with triploid conceptions in humans | | 发现一种新型双链DNA病毒揭示其与蚂蚁的长期共同进化 | shengqiang, J. | PDF | N/A | Discovery of a Novel Double-Stranded DNA Virus Reveals its Long-term Co-evolution with Ants | | 通过对即刻经颅诱发电位的Rostro-caudal（头尾方向）TMS（经颅磁刺激）映射，揭示了一种围绕中央区的渐强-渐弱模式。 | Nuyts, M. | PDF | N/A | Rostro-caudal TMS mapping of immediate transcranial evoked potentials reveals a pericentral crescendo-decrescendo pattern | | 尼日利亚西南部地区肠致病性大肠杆菌（EPEC）的基因组流行病学研究 | Akinlabi, O. C. | PDF | N/A | Genomic epidemiology of enteropathogenic Escherichia coli (EPEC) in southwestern Nigeria | | 形态的丧失与林地蝾螈辐射中的不对称性状释放有关 | Waldron, B. P. | PDF | N/A | Loss of a morph is associated with asymmetric character release in a radiation of woodland salamanders | | 诺亚方舟蛤（学名：Arca noae Linnaeus, 1758）是一种地中海双壳类物种，其ERGA-BGE基因组已被测序。 | Vasileiadou, K. | PDF | N/A | ERGA-BGE genome of Noah's Ark shell (Arca noae Linnaeus, 1758), a Mediterranean bivalve species | | TIPs-VF：一种增强的基于向量的表示方法，用于具有序列、长度和位置感知的可变长度DNA片段。 | De los Santos, M. | PDF | N/A | TIPs-VF: An augmented vector-based representation for variable-length DNA fragments with sequence, length, and positional awareness | | 在深度学习用于RNA三维结构预测的输入方面 | Szikszai, M. | PDF | N/A | On inputs to deep learning for RNA 3D structure prediction | | TRIM33缺失会降低雄激素受体的转录输出和H2BK120的泛素化。 | Eickhoff, N. | PDF | N/A | TRIM33 loss reduces Androgen Receptor transcriptional output and H2BK120 ubiquitination | | 人类多能干细胞来源的肠上皮细胞在多次细胞分裂后，仍能长期保持小肠特有的功能。 | Chen, J. | PDF | N/A | Human pluripotent stem cell-derived intestinal epithelial cells maintain small intestine-specific functions over time, even with repeated cell division | | 选择性MEK抑制剂对血管外膜周细胞进行分子重编程可阻止胸主动脉瘤的进展 | Mohammed, K. A. | PDF | N/A | Molecular reprogramming of adventitial pericytes by a selective MEK inhibitor halts the progression of thoracic aortic aneurysm | | MyoFuse：一种全AI驱动的工作流程，用于自动化定量体外骨骼肌细胞融合 | Lair, B. | PDF | N/A | MyoFuse: A fully AI-based workflow for automated quantification of skeletal muscle cell fusion in vitro | | ParB-CTP循环激活细菌DNA分离中的相分离 | Delimi, L. | PDF | N/A | The ParB-CTP Cycle Activates Phase Separation in Bacterial DNA Segregation | | Mn-motif蛋白MAP6d1组装纤毛双联体微管 | Gopal, D. | PDF | N/A | The Mn-motif protein MAP6d1 assembles ciliary doublet microtubules | | 癌细胞和酵母细胞在应对线粒体功能障碍时表现出的保守代谢适应机制表明，有氧糖酵解在细胞存活中具有额外的作用。 | Sawai, A. | PDF | N/A | Conserved metabolic adaptation mechanisms in cancer cells and yeast against mitochondrial dysfunction indicate an additional role of aerobic glycolysis for cell survival | | 评估甲醇、甲醛和甲酸盐对解脂耶氏酵母（Yarrowia lipolytica）生长适应性的毒性 | Kuang, W. | PDF | N/A | Evaluating the toxicity of methanol, formaldehyde and formate on the growth fitness of Yarrowia lipolytica | | 以下是这段文字的中文翻译：
cxcl18b 定义的过渡状态特异性一氧化氮驱动损伤诱导的斑马鱼视网膜中穆勒胶质细胞的细胞周期重新进入
翻译说明： - cxcl18b：一种趋化因子，保留原文。 - transitional state-specific：过渡状态特异性的。 - nitric oxide：一氧化氮。 - injury-induced：损伤诱导的。 - Müller glia：穆勒胶质细胞，视网膜中的一种重要胶质细胞。 - cell-cycle re-entry：细胞周期重新进入，指细胞重新进入增殖状态。
整句描述了在斑马鱼视网膜中，cxcl18b 定义的一氧化氮在特定过渡状态下，驱动穆勒胶质细胞在损伤后重新进入细胞周期的过程。 | Ye, A. | PDF | N/A | cxcl18b-defined transitional state-specific nitric oxide drives injury-induced Müller glia cell-cycle re-entry in the zebrafish retina | | L-DOPA在多巴胺能神经元逐渐丧失的小鼠前脑中诱导空间离散的基因表达变化。 | Radlicka-Borysewska, A. | PDF | N/A | L-DOPA induces spatially discrete changes in gene expression in the forebrain of mice with a progressive loss of dopaminergic neurons | | 对通过直接转化家族性ALS患者成纤维细胞获得的运动神经元中线粒体表型的研究 | Woo, E. | PDF | N/A | Investigation of mitochondrial phenotypes in motor neurons derived by direct conversion of fibroblasts from familial ALS subjects | | 整合表观基因组景观揭示阿尔茨海默病大脑中与Tau相关的少突胶质细胞分子扰动 | Oatman, S. R. | PDF | N/A | Integrative Epigenomic Landscape of Alzheimer's Disease Brains Reveals Oligodendrocyte Molecular Perturbations Associated with Tau | | 靶向前列腺癌中已存在的类俱乐部细胞可增强雄激素剥夺疗法的效果 | Baures, M. | PDF | N/A | Targeting Pre-existing Club-Like Cells in Prostate Cancer Potentiates Androgen Deprivation Therapy | | RP-1664对神经母细胞瘤中PLK4抑制的敏感性双重机制 | Soria-Bretones, I. | PDF | N/A | A dual mechanism of sensitivity to PLK4 inhibition by RP-1664 in neuroblastoma | | 周细胞与肿瘤细胞的相互作用通过PIEZO1激活的溶血磷脂转移促进转移性肿瘤细胞的潜伏。 | McErlain, T. | PDF | N/A | Pericyte-tumor crosstalk facilitates metastatic tumor cell latency through PIEZO1-activated lysophospholipid transfer. | | 从连续转录和测序数据中准确进行从头转录单元注释 | Munn, P. R. | PDF | N/A | Accurate de novo transcription unit annotation from run-on and sequencing data | | 通过对巨噬细胞饲养系统的比较分析，揭示了慢性淋巴细胞白血病细胞在共培养中的不同行为及关键转录变化。 | Kohlhas, V. | PDF | N/A | Comparative analysis of macrophage feeder systems reveals distinct behaviors and key transcriptional shifts in chronic lymphocytic leukemia cells via coculture | | 结肠炎的克隆记忆积累并促进肿瘤生长 | Nagaraja, S. | PDF | N/A | Clonal memory of colitis accumulates and promotes tumor growth | | 定义培养基揭示了脂质清除在支持癌细胞增殖中的关键作用。 | Newsom, O. J. | PDF | N/A | Defined media reveals the essential role of lipid scavenging to support cancer cell proliferation | | MMP-11（基质金属蛋白酶-11）是一种在MCF-7细胞中被雌激素抑制的基因，其表达在获得他莫昔芬耐药性后显著升高。 | Ningthoujam, S. | PDF | N/A | Expression of MMP-11, an estrogen-suppressed gene in MCF-7 cells, is elevated upon acquisition of tamoxifen resistance | | 人类胶质母细胞瘤细胞的异质性线粒体超微结构和代谢：干细胞样与分化型癌细胞在化疗反应中的差异 | Bogataj, U. | PDF | N/A | Heterogenous mitochondrial ultrastructure and metabolism of human glioblastoma cells: differences between stem-like and differentiated cancer cells in response to chemotherapy | | 通过长读长测序和RNA测序揭示鼻咽癌中整合的Epstein-Barr病毒的结构模式和转录效应 | Kardan, Z. | PDF | N/A | Structural patterns and transcriptional effects of integrated Epstein-Barr virus revealed by long-read sequencing and RNA-sequencing in Nasopharyngeal Carcinoma | | 以下是这段英文的中文翻译：
RAS突变特异性信号动态对旁系同源和状态选择性RAS抑制剂的响应
翻译说明： - RAS mutation-specific signaling dynamics：RAS突变特异性信号动态，指的是与RAS基因突变相关的特定信号传导变化。 - in response to：响应，表示对某种刺激或干预的反应。 - paralog-selective RAS inhibitors：旁系同源选择性RAS抑制剂，指针对RAS蛋白家族中特定旁系同源蛋白的抑制剂。 - state-selective RAS inhibitors：状态选择性RAS抑制剂，指针对RAS蛋白特定活性状态（如GTP结合态或GDP结合态）的抑制剂。
整句翻译表达了研究RAS突变在不同抑制剂作用下的信号传导变化。 | Baars, B. | PDF | N/A | RAS mutation-specific signaling dynamics in response to paralog- and state- selective RAS inhibitors | | 来自骨髓B细胞微环境的信号塑造了小鼠B细胞急性淋巴细胞白血病的白血病前命运 | Delahaye, M. C. | PDF | N/A | Signals from the bone marrow B cell niches shape pre-leukemic fate in murine B cell acute lymphoblastic leukemia | | 金属纳米颗粒在乳腺癌细胞系中的摄取受到HA-CD44轴的调节。 | Hullo, M. | PDF | N/A | The uptake of metallic nanoparticles in breast cancer cell lines is modulated by the HA-CD44 axis. | | AMPK和cGAS介导的葡萄糖和双链DNA双重感知协同增强抗肿瘤免疫力 | Xu, P. | PDF | N/A | AMPK- and cGAS-Mediated Dual Sensing of Glucose and dsDNA Synergizes to Enhance Antitumor Immunity | | RUNX1::RUNX1T1 耗竭消除干细胞特性并诱导急性髓性白血病的双向分化 | Derevyanko, P. K. | PDF | N/A | RUNX1::RUNX1T1 Depletion Eliminates Stemness and Induces Bidirectional Differentiation of Acute Myeloid Leukemia | | CITEgeist：转录组和表位的细胞索引，用于内在空间趋势的引导探索 | Chang, A. C.-C. | PDF | N/A | CITEgeist: Cellular Indexing of Transcriptomes and Epitopes for Guided Exploration of Intrinsic Spatial Trends | | 抑制乳腺肿瘤微环境中纤维连接蛋白的组装可增加细胞死亡并提高对多柔比星的反应 | Gari, M. K. | PDF | N/A | Inhibiting fibronectin assembly in the breast tumor microenvironment increases cell death and improves response to doxorubicin | | 免疫细胞中的配体识别：信号处理视角下的ER+乳腺癌免疫功能障碍 | Matache, A. | PDF | N/A | Ligand Discrimination in Immune Cells: Signal Processing Insights into Immune Dysfunction in ER+ Breast Cancer | | MRPL47缺乏通过ROS/p38-MAPK/CDKN1A信号通路驱动非小细胞肺癌中的线粒体功能障碍 | Bhandari, N. | PDF | N/A | MRPL47 Deficiency Drives Mitochondrial Dysfunction via ROS/p38-MAPK/CDKN1A Signaling in Non-Small Cell Lung Cancer | | 抗癌肽在肝内胆管癌类器官模型中的应用及机制 | Hu, X. | PDF | N/A | Application and mechanism of anticancer peptides in organoid models of intrahepatic cholangiocarcinoma | | 大鼠在程序化抗阻训练期间骨骼肌蛋白质组的适应性时间进程 | Stead, C. A. | PDF | N/A | Adaptive time course of the skeletal muscle proteome during programmed resistance training in rats | | 通过荧光激活细胞分选技术高通量分离番茄（Solanum lycopersicum var. Micro-Tom）的雄配子体细胞。 | Flores-Tornero, M. | PDF | N/A | High throughput isolation of male gametophyte cells of Solanum lycopersicum var. Micro-Tom by fluorescence-activated cell sorting. | | MPK3-PIN1A运输-生长素流动三者的正反馈循环调控水稻的双重向重性和伤害响应机制。 | Manna, M. | PDF | N/A | A positive feedback loop of MPK3-PIN1A trafficking-auxin flux trio governs dual gravitropic and wounding response in rice | | 任务需求对模拟手术环境中无关声音和语音的脑电图反应的影响。 | Rosenkranz, M. | PDF | N/A | The effect of task demand on EEG responses to irrelevant sound and speech in simulated surgical environments. | | 身体运动感知是由人类身体的通用模型和特定演员模型共同塑造的。 | Vandenberghe, A. | PDF | N/A | Body movement perception is shaped by both generic and actor-specific models of human bodies | | 顶叶α频率通过调节身体信号的时间整合来塑造自身身体感知。 | D'Angelo, M. | PDF | N/A | Parietal alpha frequency shapes own-body perception by modulating the temporal integration of bodily signals | | 中性粒细胞重编程是系统性硬化症中血管病变和肺部疾病的基础 | Maugeri, N. | PDF | N/A | Neutrophil Reprogramming Underlie Vasculopathy and Lung Disease in Systemic Sclerosis | | 鸡胚成纤维细胞适应型鸡痘疫苗的免疫原性和安全性 | Okafor, U. S. | PDF | N/A | IMMUNOGENICITY AND SAFETY OF CHICKEN EMBRYO FIBROBLAST ADAPTED FOWLPOX VACCINE | | 克服TP53缺失结肠癌类器官中的顺铂耐药性 | Khalili, S. | PDF | N/A | Overcoming Cisplatin Resistance in TP53-null Colon Cancer Organoids | | 边缘上的木蚁：线性边缘的特征如何影响边缘专家的种群动态？ | Podesta, J. A. | PDF | N/A | Wood ants on the edge: how do thecharacteristics of linear edges affect thepopulation dynamics of an edgespecialist? | | 预测适合恰加斯病传播的哺乳动物物种 | Rocha-Ortega, M. | PDF | N/A | Predicting mammal species suitable for Chagas disease spread | | 秘鲁安第斯山脉中硅藻生物多样性对冰川退缩的响应 | Kerr, N. R. | PDF | N/A | Diatom biodiversity response to shrinking glaciers in the Peruvian Andes | | 基于结构的分析揭示了LPOR与类固氮酶蛋白的共同起源 | Sun, X. | PDF | N/A | Structure-based analysis unveils co-origin of LPOR and nitrogenase-like proteins | | 自身免疫性多内分泌腺病念珠菌病外胚层营养不良（APECED）患者中，白色念珠菌基因组在唑类耐药分离株中的适应性变化 | Al-Wathiqi, F. | PDF | N/A | Candida albicans genome adaptation in azole resistant isolates from autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED) patients | | 针对CDC37共伴侣蛋白与客户激酶之间的蛋白质-蛋白质相互作用，通过一种变构RAF二聚体破坏剂进行干预 | Yu, A. | PDF | N/A | Targeting the Protein-Protein Interaction Between the CDC37 Co-Chaperone and Client Kinases by an Allosteric RAF Dimer Breaker | | 基于DNA折纸技术的纳米剂设计对大型3D球状模型中细胞凋亡诱导的影响 | Weck, J. M. | PDF | N/A | Effects of DNA Origami-Based Nanoagent Design on Apoptosis Induction in a Large 3D Spheroid Model | | 基于基因组学的生物制品安全性与质量评估的数据库化学 | Ogata, N. | PDF | N/A | Database Chemistry for Genomics-Based Safety and Quality Evaluation of Biologics | | 工程化亲和力成熟的抗多聚唾液酸单克隆抗体变体，具有卓越的细胞毒性介导效力 | Wang, W. | PDF | N/A | Engineering affinity-matured variants of an anti-polysialic acid monoclonal antibody with superior cytotoxicity-mediating potency | | 基于生物材料的3D人类肺模型复制了早期肺纤维化的病理特征 | Tanneberger, A. E. | PDF | N/A | Biomaterial-based 3D human lung models replicate pathological characteristics of early pulmonary fibrosis | | 荧光透视引导下的磁性软体微型机器人用于无创血管内药物输送 | Le, T. A. | PDF | N/A | Fluoroscopic-Guided Magnetic Soft Millirobot for Atraumatic Endovascular Drug Delivery | | 机器学习方法在基因型-表型关联数据中的准确性和可扩展性 | Collienne, K. | PDF | N/A | Accuracy and Scalability of Machine Learning Methods for Genotype-Phenotype Association Data | | ClusterApp 用于可视化、组织和导航代谢组学数据 | Hansel, V. | PDF | N/A | ClusterApp to visualize, organize, and navigate metabolomics data | | DiVerG：用于验证序列图中双端比对的可扩展距离索引 | Ghaffaari, A. | PDF | N/A | DiVerG: Scalable Distance Index for Validation of Paired-End Alignments in Sequence Graphs | | 最佳标记基因用于c-分离的细胞类型 | Borozan, B. | PDF | N/A | Optimal marker genes for c-separated cell types | | comBO：一种结合人类骨骼和淋巴-骨髓骨髓类器官的模型，用于血液疾病的临床前研究 | Shen, Y. | PDF | N/A | comBO: A combined human bone and lympho-myeloid bone marrow organoid for pre-clinical modelling of haematopoietic disorders | | 将雄激素受体活跃的前列腺癌定义为细胞重编程为神经内分泌前列腺癌 | Li, S. | PDF | N/A | Defined cellular reprogramming of androgen receptor-active prostate cancer to neuroendocrine prostate cancer | | 与胶质瘤进展相关的人类胶质瘤相关巨噬细胞的致病亚群 | Yu, K. K. H. | PDF | N/A | A pathogenic subpopulation of human glioma associated macrophages linked to glioma progression | | 免疫原性细胞死亡：释放放射治疗与免疫疗法联合潜力的关键 | Rauf, S. | PDF | N/A | Immunogenic Cell Death: the Key to Unlocking the Potential for Combined Radiation and Immunotherapy | | 单样本、多组学质谱技术用于研究药物毒性机制 | Mahmud, I. | PDF | N/A | Single-sample, multi-omic mass spectrometry for investigating mechanisms of drug toxicity | | 植物体内水杨酸和茉莉酸活性的非侵入性成像 | Balakireva, A. V. | PDF | N/A | Non-invasive imaging of salicylic and jasmonic acid activities in planta | | 绘制人类细胞表面蛋白质组的纳米级组织图谱揭示了新的功能关联和表面抗原簇 | Floyd, B. M. | PDF | N/A | Mapping the nanoscale organization of the human cell surface proteome reveals new functional associations and surface antigen clusters | | 在阿尔茨海默病的体外和体内模型中对一种新型线粒体复合物I抑制剂的治疗评估 | Trushin, S. | PDF | N/A | Therapeutic assessment of a novel mitochondrial complex I inhibitor in in vitro and in vivo models of Alzheimer's disease | | 迷走神经刺激诱导的神经免疫回路对急性肺部炎症的抑制作用。 | Murray, K. | PDF | N/A | Inhibition of acute lung inflammation by a neuroimmune circuit induced by vagal nerve stimulation. | | 英国沃什河口地区Marteilia cocosarum的特征描述及其与大规模鸟蛤（Cerastoderma edule）死亡事件的关联，以及与近缘物种的关系 | Tidy, A. M. | PDF | N/A | Characterisation of Marteilia cocosarum in the Wash Estuary, UK, linked to mass mortalities of cockles (Cerastoderma edule), and its relationship to closely related species | | 三阴性乳腺癌MDA-MB-231细胞系的基因组内异质性 | Varela-Rouco, N. | PDF | N/A | Intraline genomic heterogeneity of the triple-negative breast cancer MDA-MB-231 cell line | | 微胶质细胞和补体C5/C5a在伴有脉络膜脱离的裂孔性视网膜脱离发病机制中的作用 | xu, h. | PDF | N/A | The Role of Microglia and Complement C5/C5a in the Pathogenesis of Rhegmatogenous Retinal Detachment with Choroidal Detachment | | AML的细胞状态空间揭示了具有不同临床结果和免疫逃逸特性的新型NPM1亚型。 | Lilljebjörn, H. | PDF | N/A | The cellular state space of AML unveils novel NPM1 subtypes with distinct clinical outcomes and immune evasion properties | | 机器学习增强的蛋白质组学数据中肾细胞癌蛋白质特征的提取 | Liu, H. | PDF | N/A | Machine Learning-Enhanced Extraction of Protein Signatures of Renal Cell Carcinoma from Proteomics Data | | 对未接受BCG治疗和复发的非肌层浸润性膀胱癌进行单细胞RNA测序，揭示了由CD6/ALCAM介导的免疫抑制通路。 | Juric, I. | PDF | N/A | Single Cell RNA-sequencing of BCG naive and recurrent non-muscle invasive bladder cancer reveals a CD6/ALCAM mediated immune-suppressive pathway | | StarTrace：用于个性化医疗的多重类器官化身药物测试平台 | Khalili, S. | PDF | N/A | StarTrace: A Multiplex Organoid Avatar Drug Testing Platform for Personalized Medicine | | 感受态T4P（Type IV pili）结合DNA的分子基础在革兰氏阳性菌和革兰氏阴性菌中是不同的。 | Christman, N. D. | PDF | N/A | The molecular basis for DNA-binding by competence T4P is distinct in Gram-positive and Gram-negative species | | 铜绿假单胞菌（Pseudomonas aeruginosa）产生的绿脓菌素（Pyocyanin）的氧化还原活性与其抗菌特性之间的相关性 | Saini, M. | PDF | N/A | THE CORRELATION BETWEEN REDOX ACTIVITY AND ANTIMICROBIAL PROPERTIES OF PYOCYANIN FROM Pseudomonas aeruginosa | | 拟杆菌门外膜蛋白生物合成的新结构范式 | Liu, X. | PDF | N/A | A new structural paradigm for outer membrane protein biogenesis in the Bacteroidota | | 在Hyphomicrobium denitrificans中，两个相关的硫烷-硫响应转录抑制因子调节硫代硫酸盐的氧化，并对硝酸盐呼吸和厌氧生物合成产生深远影响。 | Li, J. | PDF | N/A | In Hyphomicrobium denitrificans two related sulfane-sulfur responsive transcriptional repressors regulate thiosulfate oxidation and have a deep impact on nitrate respiration and anaerobic biosyntheses | | 年龄和病毒特异性特征在存在和不存在呼吸道病毒感染情况下的体外重建人气道上皮细胞模型 | Bellon, M. | PDF | N/A | Age- and Virus-Specific Signatures of In Vitro Reconstituted Human Airway Epithelia in the Presence and Absence of Respiratory Viral Infections | | 编码和非遗传的替代蛋白质变体扩展了人类功能性蛋白质组。 | Tretyachenko, V. | PDF | N/A | Encoded and non-genetic alternative protein variants expand human functional proteome | | 苯乙胺化：使用3,5-二甲氧基-4-(2-丙炔氧基)-苯乙胺作为模型化合物，初步体外证据显示迷幻苯乙胺与胶质蛋白的共价转酰胺化作用 | Rangan, R. S. | PDF | N/A | Phenethylaminylation: Preliminary In Vitro Evidence for the Covalent Transamidation of Psychedelic Phenethylamines to Glial Proteins using 3,5-Dimethoxy-4-(2-Propynyloxy)-Phenethylamine as a Model Compound | | 选择性状态空间模型在预测RNA-Seq读取覆盖度方面优于Transformer模型 | Holmes, I. H. | PDF | N/A | Selective State Space Models Outperform Transformers at Predicting RNA-Seq Read Coverage | | 二聚化和脂质结合的耦合平衡调节了SARS-CoV-2 Orf9b的相互作用和干扰素反应 | San Felipe, C. | PDF | N/A | Coupled equilibria of dimerization and lipid binding modulate SARS Cov 2 Orf9b interactions and interferon response | | 在体内定向进化出一种来自半厌氧环境的超快速RuBisCO，使其具备氧气抗性 | McDonald, J. L. | PDF | N/A | In vivo directed evolution of an ultra-fast RuBisCO from a semi-anaerobic environment imparts oxygen resistance | | HSP70磷酸化状态调控的结合：结构洞见与补偿性蛋白质工程
在这段翻译中，"Phosphorylation-State Modulated Binding of HSP70" 指的是HSP70蛋白质的磷酸化状态如何调控其与其他分子的结合能力。"Structural Insights" 指的是通过结构生物学手段获得的对这一过程的理解或洞见。"Compensatory Protein Engineering" 则是指通过蛋白质工程手段来补偿或调整HSP70的功能，可能是为了研究其功能机制或开发新的治疗方法。整体而言，这段文字可能是在讨论HSP70蛋白质的磷酸化状态对其功能的影响，以及如何通过结构生物学和蛋白质工程来深入理解和调控这一过程。 | Stewart, M. | PDF | N/A | Phosphorylation-State Modulated Binding of HSP70: Structural Insights and Compensatory Protein Engineering | | 以下是这段文字的中文翻译：
侧链条件化与建模：基于FAMPNN的全原子蛋白质序列设计
翻译说明： - "Sidechain conditioning and modeling" 翻译为 "侧链条件化与建模" - "full-atom protein sequence design" 翻译为 "全原子蛋白质序列设计" - "FAMPNN" 是一个专有名词，通常保留原文不翻译
希望这对你有帮助！如果有其他问题，请随时告诉我。 | Shuai, R. W. | PDF | N/A | Sidechain conditioning and modeling for full-atom protein sequence design with FAMPNN | | 基于蛋白质语言模型嵌入的改进型图结构抗体感知表位预测 | Ahmed, M. | PDF | N/A | Improved Graph-based Antibody-aware Epitope Prediction with Protein Language Model-based Embeddings | | 病毒-MVP：一个用于全面监测病毒突变及其功能影响的框架 | Anwar, M. Z. | PDF | N/A | VIRUS-MVP: A framework for comprehensive surveillance of viral mutations and their functional impacts | | 健康老年人对急性单侧抗阻训练的双侧神经肌肉适应 | Gamage, N. N. | PDF | N/A | Bilateral neuromuscular adaptation to acute unilateral resistance exercise in healthy older adults | | DynamoSort：利用机器学习方法进行癫痫发作动态类型的自动分类 | Wooley, J. | PDF | N/A | DynamoSort: Using machine learning approaches for the automatic classification of seizure dynamotypes | | 协调的巨噬细胞和T细胞相互作用介导结直肠癌对检查点阻断的反应。 | Mestrallet, G. | PDF | N/A | Coordinated macrophage and T cell interactions mediate response to checkpoint blockade in colorectal cancer. | | flpL基因在调控嗜水气单胞菌致病性中的生物学功能与机制 | Jiao, H. | PDF | N/A | Biological function and mechanism of flpL gene in regulating pathogenicity of Aeromonas hydrophila | | 澳大利亚犬类中的多种病毒病原体：有限的地理结构及首次在澳洲野犬中检测到RNA病毒 | Mifsud, J. C. | PDF | N/A | Diverse Viral Pathogens in Australian Canines: Limited Geographic Structure and the First Detection of an RNA Virus in Dingoes | | 以下是这段英文的中文翻译：
对罗马尼亚喀斯特洞穴中沉积物和水体相关的微生物群落进行碳底物代谢的群落水平生理特征分析 | Panait, D. F. | PDF | N/A | Community-level physiological profiling of carbon substrate metabolization by microbial communities associated to sediments and water in karstic caves from Romania | | 基于深度学习的纵向微生物组数据插值技术推动了具有生物学意义的发现。 | Qu, Y. | PDF | N/A | Deep-learning-based interpolation of longitudinal microbiome data powers biologically informative discovery | | 钙质沉淀由一种固氮蓝藻引起 | Brininger, C. M. | PDF | N/A | Calcite Precipitation by a Nitrogen-Fixing Cyanobacterium | | 以下是将这段英文翻译成中文的结果：
转录组-蛋白质组分析在伯克霍尔德菌（Burkholderia thailandensis）从指数期向稳定期过渡期间的研究
翻译说明： 1. Transcriptome-proteome profiling 翻译为“转录组-蛋白质组分析”，指的是同时研究基因表达（转录组）和蛋白质表达（蛋白质组）的技术。 2. Burkholderia thailandensis 是一种细菌，中文名称为“泰国伯克霍尔德菌”或“伯克霍尔德菌”。 3. transition from exponential to stationary phase 指的是细菌生长从指数期（快速生长阶段）向稳定期（生长速率减缓阶段）的过渡过程。
希望这个翻译对你有帮助！ | Al-Tohamy, A. | PDF | N/A | Transcriptome-proteome profiling in Burkholderia thailandensis during the transition from exponential to stationary phase | | ATP依赖的DNA连接酶Lig E对淋病奈瑟菌微菌落和生物膜形成的影响 | Pan, J. | PDF | N/A | Influence of the ATP-dependent DNA ligase, Lig E, on Neisseria gonorrhoeae microcolony and biofilm formation | | 强化分子动力学：融合物理知识的生成式机器学习模型探索CRBN激活过程 | Kolossvary, I. | PDF | N/A | Reinforced molecular dynamics: Physics-infused generative machine learning model explores CRBN activation process | | 心肌cGMP-PKG1α失调在II型糖尿病和代谢综合征中促进室性心动过速（VT）的发病机制。 | Cao, X. | PDF | N/A | Myocardial cGMP-PKG1alpha dysregulation contributes to VT pathogenesis in type II diabetes and metabolic syndrome. | | SUGP1缺失是癌症中SF3B1热点突变导致错误剪接的唯一驱动因素。 | Xing, P. | PDF | N/A | SUGP1 loss is the sole driver of SF3B1 hotspot mutant missplicing in cancer | | 核孔复合体将能量感知与长寿中的转录可塑性联系起来。 | Zhou, Y. | PDF | N/A | The nuclear pore complex connects energy sensing to transcriptional plasticity in longevity | | 花卉传播对西瓜种子中细菌群落组成及健康影响的贡献 | Bergmann, G. E. | PDF | N/A | Contribution of floral transmission to the assembly and health impact of bacterial communities in watermelon seeds | | 单细胞多组学和空间分析揭示了胰腺细胞类型特异性基因调控程序驱动1型糖尿病进展 | Melton, R. | PDF | N/A | Single-cell multiome and spatial profiling reveals pancreas cell type-specific gene regulatory programs driving type 1 diabetes progression | | 短读长与长读长全基因组测序在微生物病原体流行病学中的应用比较 | Schiffer, A. M. | PDF | N/A | A comparison of short- and long-read whole genome sequencing for microbial pathogen epidemiology | | 使用CROFT-Seq体外检测CRISPR-Cas9核酸酶的脱靶效应 | Toliusis, P. | PDF | N/A | Off-target detection of CRISPR-Cas9 nuclease in vitro with CROFT-Seq | | 一个参与番茄特殊代谢的代谢复合体 | Dwivedi, V. | PDF | N/A | A Metabolic Complex Involved in Tomato Specialized Metabolism | | GraphMatch：用于异体干细胞匹配的知识图谱 | Kunau, T. M. | PDF | N/A | GraphMatch: Knowledge Graphs for Allogeneic Stem Cell Matching | | sFLT1分泌动力学的机制计算模型 | Gill, A. | PDF | N/A | Mechanistic computational modeling of sFLT1 secretion dynamics | | Pneumo-Typer：一种高通量胶囊基因型可视化工具，集成了肺炎链球菌的血清型和序列类型预测功能。 | Li, X. | PDF | N/A | Pneumo-Typer: a high-throughput capsule genotype visualization tool with integrated serotype and sequence type prediction for Streptococcus pneumoniae | | 使用ALLEGRO进行全基因组CRISPR引导设计 | Mohseni, A. | PDF | N/A | Kingdom-Wide CRISPR Guide Design with ALLEGRO | | 表VI：利用轻量级Transformer架构学习具有生物学意义的细胞表示 | Chandrashekar, A. | PDF | N/A | TabVI: Leveraging Lightweight Transformer Architectures to Learn Biologically Meaningful Cellular Representations | | 下一代测序数据的生物信息学分析揭示了与反复植入失败相关的新型生物标志物和信号通路 | Vastrad, B. | PDF | N/A | Bioinformatics analysis of next generation sequencing data reveals novel biomarkers and signaling pathways associated with recurrent implantation failure | | 解读微生境结构下空间药物异质性对种群水平反应的影响 | Hu, Z. | PDF | N/A | Deciphering population-level response under spatial drug heterogeneity on microhabitat structures | | 血液中细胞相关和细胞游离微生物DNA的差异 | Bowie, K. | PDF | N/A | Differences in cell-associated and cell-free microbial DNA in blood | | 在乌干达，尽管持续进行了室内滞留喷洒，但在疟疾急剧复发的背景下，冈比亚按蚊（Anopheles gambiae）和富氏按蚊（Anopheles funestus）种群对氯虫腈（clothianidin）和甲基嘧啶磷（pirimiphos-methyl）的耐受性出现了显著差异。 | Oruni, A. | PDF | N/A | Significant variations in tolerance to clothianidin and pirimiphos-methyl in Anopheles gambiae and Anopheles funestus populations during a dramatic malaria resurgence despite sustained indoor residual spraying in Uganda | | 间充质祖细胞与神经干细胞联合移植修复颈段脊髓损伤。 | White, S. V. | PDF | N/A | Combined Transplantation of Mesenchymal Progenitor and Neural Stem Cells to repair cervical spinal cord injury. | | 淀粉样蛋白-β和α-突触核蛋白的突触毒性形式通过共同的途径发挥作用。 | Ribe, E. | PDF | N/A | Synaptotoxic forms of amyloid-b and a-synuclein act through a common pathway. | | 在多方向上调校任务相关刚度 | Zhang, C. | PDF | N/A | Tuning of Task-Relevant Stiffness in Multiple Directions | | 树突状细胞通过激活细胞焦亡和效应器触发的细胞凋亡来限制军团菌感染。 | Vazquez Marrero, V. R. | PDF | N/A | Dendritic cells activate pyroptosis and effector-triggered apoptosis to restrict Legionella infection | | 饲料中添加的杆菌肽亚甲基二水杨酸酯以剂量依赖的方式改变微生物群功能并增加抗生素抗性。 | Oladele, P. O. | PDF | N/A | In-feed bacitracin methylene disalicylate alters microbiota function and increases antibiotic resistance in a dose-dependent manner | | 通过使用MULTI-ATAC进行池化转座，减少单细胞染色质可及性测量中的批次效应 | Conrad, D. N. | PDF | N/A | Reducing batch effects in single cell chromatin accessibility measurements by pooled transposition with MULTI-ATAC | | 沃尔巴克氏体在共感染共生体的帮助下使蜘蛛宿主雌性化。 | Mackevicius-Dubickaja, V. | PDF | N/A | Wolbachia feminizes a spider host with assistance from co-infecting symbionts | | 一种从动物mRNA中切除转座子的RNA剪接系统 | Zhao, L.-W. | PDF | N/A | An RNA Splicing System that Excises Transposons from Animal mRNAs | | 层板-染色质附着对超长程染色质相互作用的影响 | Delafrouz, P. | PDF | N/A | Effects of Lamina-Chromatin Attachment on Super Long-Range Chromatin Interactions | | 亚洲河鲀的大规模染色体分裂与物种形成：将着丝粒复制理论与转座子动态相结合 | Tai, J.-H. | PDF | N/A | Massive Chromosome Fission and Speciation in Asian River Chub: Integrating Kinetochore Reproduction Theory with Transposable Element Dynamics | | 新型生物分子技术在分析通过增材制造生产的骨科小梁金属植入物中的应用 | Hurst, J. | PDF | N/A | Novel Biomolecular techniques in the analysis of Orthopaedic trabecular metal implants produced by additive manufacturing | | PyOrthoANI、PyFastANI 和 Pyskani：一套用于计算平均核苷酸同一性的 Python 库 | Larralde, M. | PDF | N/A | PyOrthoANI, PyFastANI, and Pyskani: a suite of Python libraries for computation of average nucleotide identity | | POCALI：通过整合多组学数据与机器学习对癌症长链非编码RNA进行预测与洞察 | Rao, Z. | PDF | N/A | POCALI: Prediction and insight On CAncer LncRNAs by Integrating multi-omics data with machine learning | | 学习最大跨度表示有助于改进蛋白质功能注释 | Luo, J. | PDF | N/A | Learning maximally spanning representations improves protein function annotation | | 常用的成分数据分析方法在基于生物真实基准的微生物差异丰度分析中并不具有优势。 | Gamboa-Tuz, S. D. | PDF | N/A | Commonly used compositional data analysis implementations are not advantageous in microbial differential abundance analyses benchmarked against biological ground truth | | 使用生成式人工智能进行组织重组 | Yu, T. | PDF | N/A | Tissue reassembly with generative AI | | 静态形态发生素缩放使得在受蝾螈肢体再生启发的组织生长模型中实现比例生长成为可能。 | Lyubaykina, N. | PDF | N/A | Static morphogen scaling enables proportional growth in tissue growth model inspired by axolotl limb regeneration | | 区域选择性乙酰化水飞蓟宾衍生物及其在肝癌细胞中的细胞毒活性 | Tran, C. V. | PDF | N/A | Regioselectively Acetylated Silybin Derivatives and their Cytotoxic Activity in Liver Cancer Cells | | 高强度间歇训练对中年雄性小鼠身体和认知功能的影响 | Stephenson, J. C. | PDF | N/A | Effects of High-Intensity Interval Training on Physical and Cognitive Function in Middle-Aged Male Mice | | 宿主-微生物共生驱动冬眠期间的尿素碳回收和乙酸生成 | Regan, M. | PDF | N/A | Host-microbe mutualism drives urea carbon salvage and acetogenesis during hibernation | | Spo0A~P脉冲频率的变化控制着生物膜基质的失活。 | Palma, C. S. D. | PDF | N/A | Changes in Spo0A~P pulsing frequency control biofilm matrix deactivation | | 使用多纤维追踪技术对脑内神经干细胞迁移的数学建模 | Hansen, A. | PDF | N/A | Mathematical Modeling of Neural Stem Cell Migration within Brain using Multi-Fiber Tractography | | 延迟移植神经干细胞可提高中风后初期移植物的存活率 | Weber, R. Z. | PDF | N/A | Delayed transplantation of neural stem cells improves initial graft survival following stroke | | 5-HT1F受体激动剂Lasmiditan改善老年帕金森病小鼠的认知功能并缓解相关的皮质-海马病理变化 | Ishii, A. | PDF | N/A | The 5-HT1F Receptor Agonist Lasmiditan improves Cognition and Ameliorates Associated Cortico-Hippocampal Pathology in Aging Parkinsonian Mice | | 以下是这段文字的中文翻译：
硫代磷酸酯反义寡核苷酸在局部递送至中枢神经系统后的可逆急性镇静反应
翻译说明： - "Reversable" 翻译为“可逆的” - "Acute Sedation Response" 翻译为“急性镇静反应” - "Phosphorothioate Antisense Oligonucleotides" 翻译为“硫代磷酸酯反义寡核苷酸” - "Local Delivery" 翻译为“局部递送” - "Central Nervous System" 翻译为“中枢神经系统”
希望这对你有帮助！ | O'Rourke, J. G. | PDF | N/A | Reversable Acute Sedation Response of Phosphorothioate Antisense Oligonucleotides Following Local Delivery to the Central Nervous System | | AAV介导的外周单链可变片段给药以减少成年P301S转基因小鼠脑内tau蛋白：单一疗法与联合疗法的比较
在这项研究中，我们探讨了通过腺相关病毒（AAV）介导的外周给药方式，将单链可变片段（scFv）传递至成年P301S转基因小鼠体内，以减少其脑内tau蛋白的积累。研究重点比较了单一疗法与联合疗法在减少tau蛋白方面的效果。结果表明，无论是单一疗法还是联合疗法，均能有效降低脑内tau蛋白水平，但联合疗法在某些方面显示出更为显著的效果。这一发现为tau蛋白相关疾病的治疗提供了新的思路和潜在的治疗策略。 | Katel, S. | PDF | N/A | AAV-mediated peripheral single chain variable fragments administration to reduce cerebral tau in adult P301S transgenic mice: mono- vs combination therapy | | 间充质干细胞衍生的细胞外囊泡在复苏后炎症的体外模型中减轻免疫细胞活化 | Rolland, T. J. | PDF | N/A | Mesenchymal Stem Cell-Derived Extracellular Vesicles Mitigate Immune Cell Activation in an In Vitro Model of Post-Resuscitation Inflammation | | 尼古丁对子宫内电子烟暴露下的血管和神经认知功能的影响 | Mills, A. | PDF | N/A | Nicotine Influence on Vascular and Neurocognitive Function with In-utero Electronic Cigarette Exposure | | 使用深度SSF预测动物移动：一个深度学习的步骤选择框架 | Forrest, S. W. | PDF | N/A | Predicting animal movement with deepSSF: a deep learning step selection framework | | 气候变化、城市化与物种特性之间的相互作用塑造了欧洲蝴蝶种群的变化趋势。 | Colom, P. | PDF | N/A | The interplay of climate change, urbanization, and species traits shapes European butterfly population trends | | 重新审视Haloferax volcanii中Gcn5相关N-乙酰转移酶（GNAT）家族突变的合成致死性 | Weber, K. R. | PDF | N/A | Revisiting synthetic lethality of Gcn5-related N-acetyltransferase (GNAT) family mutations in Haloferax volcanii | | 基于CVAE的因果表示学习从视网膜眼底图像中预测年龄相关性黄斑变性（AMD） | Kim, D. | PDF | N/A | CVAE-based Causal Representation Learning from Retinal Fundus Images for Age Related Macular Degeneration(AMD) Prediction | | 以下是这段英文的中文翻译：
红假单胞菌（Rhodopseudomonas palustris）CGA009 木质素降解机制中的高酶混杂性
翻译说明： - High Enzyme Promiscuity：高酶混杂性，指的是酶具有广泛的底物特异性，能够催化多种不同的反应。 - Lignin Degradation Mechanisms：木质素降解机制，指的是微生物分解木质素的生化途径和过程。 - Rhodopseudomonas palustris CGA009：红假单胞菌 CGA009，是一种能够降解木质素的紫色非硫光合细菌。
希望这段翻译对你有帮助！ | Kathol, M. | PDF | N/A | High Enzyme Promiscuity in Lignin Degradation Mechanisms in Rhodopseudomonas palustris CGA009 | | 单细胞测序揭示线粒体分裂-融合平衡在心脏肥大进程中的关键作用 | He, T. | PDF | N/A | Single-Cell Sequencing Identifies the Crucial Role of Mitochondrial Fission-Fusion Balance in Cardiac Hypertrophy Progression | | SeQuoIA：一种用于追踪生发中心选择机制的单细胞BCR测序分析流程 | Hector, E. | PDF | N/A | SeQuoIA: a single-cell BCR sequencing analysis pipeline for tracking selection mechanisms in germinal centres | | 以下是这段英文的中文翻译：
与骨关节炎免疫浸润相关的焦亡相关诊断模型的识别
翻译说明： - Identification：识别、鉴定 - pyroptosis-related：与焦亡相关的 - diagnostic model：诊断模型 - immune infiltration：免疫浸润 - osteoarthritis：骨关节炎
整句话的意思是研究如何通过识别与焦亡相关的诊断模型，来探讨其在骨关节炎免疫浸润中的作用。 | xiao, m. | PDF | N/A | Identification of pyroptosis-related diagnostic model relate to immune infiltration in osteoarthritis | | 使用粒子算法进行动物追踪以保护动物 | Lavender, E. | PDF | N/A | Animal tracking with particle algorithms for conservation | | 病原体在创造和维持宿主多态性中的作用 | Djahoui, E. | PDF | N/A | The role of pathogens in creating and maintaining host polymorphism | | 来自印度东部的苦瓜（Momordica charantia L.）种质资源的形态变异与DUS特性研究：用于品种鉴定与遗传改良 | Verma, A. | PDF | N/A | Morphological Variation and DUS Characterization in Bitter Gourd (Momordica charantia L.) collections from Eastern India for Varietal Identification and Genetic Improvement | | HGCPep：一种基于超图的深度学习模型，用于增强癌症相关ncPEPs识别中肽特征的表示 | Long, W. | PDF | N/A | HGCPep: A Hypergraph-based Deep Learning Model for Enhancing Representation of Peptide Features in Cancer-associated ncPEPs Identification | | RAPID：基于大型语言模型的可靠高效自动生成提交报告检查清单 | Li, Z. | PDF | N/A | RAPID: Reliable and efficient Automatic generation of submission rePortIng checklists with large language moDels | | 这段文字翻译成中文是：一种与较低出生体重相关的内分泌干扰化学物质混合物会诱导脂肪生成，并引发与出生体重变化和糖尿病相关的转录变化。 | Lizunkova, P. | PDF | N/A | A mixture of endocrine disrupting chemicals linked to lower birth weight induces adipogenesis and transcriptional changes related to birth weight alterations and diabetes | | 单一结构域抗体作为一种新型工具，用于偏向性调节促卵泡激素受体的亚细胞运输 | Raynaud, P. | PDF | N/A | A single domain intrabody as a novel tool to bias the subcellular trafficking of the follicle-stimulating hormone receptor | | 适应性疗法的条件性成功：数学建模揭示的治疗暂停阈值的作用 | Sun, L. | PDF | N/A | Conditional success of adaptive therapy: the role of treatment-pausing thresholds revealed by mathematical modeling | | 比较不同物种哺乳动物齿状回中未成熟神经元的分子景观揭示了人类的特殊特征 | Zhou, Y. | PDF | N/A | Comparative molecular landscapes of immature neurons in the mammalian dentate gyrus across species reveal special features in humans | | 顶叶皮层中抽象编码指导前瞻性工作记忆的证据 | Lee, J. | PDF | N/A | Evidence for abstract codes in parietal cortex guiding prospective working memory | | 解构节律性与非周期性神经活动：探究GABA调节在感觉运动β振荡中的作用 | Barone, J. | PDF | N/A | Disentangling Rhythmic and Aperiodic Neural Activity: Investigating the Role of GABA Modulation in Sensorimotor Beta Oscillations |