BioRxiv 2025-02-21 Papers

标题	作者	PDF链接	代码仓库	Title
YAP通过Rho-GTPase开关调控细胞迁移和侵袭。	Shah, S. R.	PDF	N/A	YAP controls cell migration and invasion through a Rho-GTPase switch
迈向基因组规模的双变量单调分类器发现	Fourquet, O.	PDF	N/A	Towards the Genome-scale Discovery of Bivariate Monotonic Classifiers
无尺度模型的染色体结构、动力学与力学	Grosse-Holz, S.	PDF	N/A	Scale-free models of chromosome structure, dynamics, and mechanics
来自北格陵兰卡普·科本哈根组的两百万年前的微生物群落	Fernandez-Guerra, A.	PDF	N/A	Two-million-year-old microbial communities from the Kap Kobenhavn Formation in North Greenland
组装、突触聚类和网络拓扑结构与可塑性相互作用，以解释皮质连接组的结构-功能关系。	Ecker, A.	PDF	N/A	Assemblies, synapse clustering and network topology interact with plasticity to explain structure-function relationships of the cortical connectome
农场：动物与机器人建模与仿真框架	Arreguit, J.	PDF	N/A	FARMS: Framework for Animal and Robot Modeling and Simulation
Med12与多种分化信号协同作用，促进胚胎干细胞中高效的谱系转换。	Fernkorn, M.	PDF	N/A	Med12 cooperates with multiple differentiation signals to facilitate efficient lineage transitions in embryonic stem cells
综合表位突变扫描数据库实现精准T细胞受体交叉反应预测	Banerjee, A.	PDF	N/A	Comprehensive epitope mutational scan database enables accurate T cell receptor cross-reactivity prediction
冷冻电镜引导的查加斯病疫苗候选物TcPOP的开放和闭合构象分析及其抗体反应特征研究	Batra, S.	PDF	N/A	Cryo-EM led analysis of open and closed conformations of Chagas vaccine candidate TcPOP and its antibody response characterisation
选择性注意与对虚拟现实教室中听觉干扰的敏感性：有与无AD(H)D成人的比较	Levy, O.	PDF	N/A	Selective attention and sensitivity to auditory disturbances in a virtually-real Classroom: Comparison of adults with and without AD(H)D
外纹状皮层在意识运动行为中的作用：一项基于快速光学成像的注册报告	Colombari, E.	PDF	N/A	The role of extra-striate areas in conscious motor behavior: a registered report with Fast-Optical Imaging
细胞外rRNA分析揭示了海洋微真核生物的下沉和细胞裂解动态	Endo, H.	PDF	N/A	Extracellular rRNA profiling reveals the sinking and cell lysis dynamics of marine microeukaryotes
伤口会引发人类基底细胞癌的侵袭性进展	Yerly, L.	PDF	N/A	Wounding triggers invasive progression in human basal cell carcinoma
额叶Theta振荡与认知灵活性：脑电图活动中的年龄相关调节	Darna, M.	PDF	N/A	Frontal Theta Oscillations and Cognitive Flexibility: Age-Related Modulations in EEG Activity
人类肠道微生物通过酶促作用裂解碳-氟键	Probst, S. I.	PDF	N/A	Enzymatic carbon-fluorine bond cleavage by human gut microbes
性别依赖性胃肠道对耐甲氧西林金黄色葡萄球菌（MRSA）的定植抵抗力依赖于微生物群和Th17细胞	Lejeune, A.	PDF	N/A	Sex-dependent gastrointestinal colonization resistance to MRSA is microbiota and Th17 dependent
信息、确定性与学习。	Harris, J. A.	PDF	N/A	Information, certainty, and learning.
双峰树突处理在篮状细胞中驱动独特的记忆相关振荡	Tzilivaki, A.	PDF	N/A	Bimodal dendritic processing in basket cells drives distinct memory-related oscillations
矿物肥料通过植物-土壤相互作用降低了山地草原系统土壤多功能性的抗旱能力	Piton, G.	PDF	N/A	Mineral fertilization reduces the drought resistance of soil multifunctionality in a mountain grassland system through plant-soil interactions
AsaruSim：一个单细胞和空间RNA-Seq纳米孔长读长模拟工作流程	Hamraoui, A.	PDF	N/A	AsaruSim: a single-cell and spatial RNA-Seq Nanopore long-reads simulation workflow
HPL-2/HP1 和 MET-2/SETDB1 结合不同的辅助因子，这些辅助因子促进异染色质焦点、基因抑制和器官发生，且不依赖于 H3K9 甲基化。	Delaney, C. E.	PDF	N/A	HPL-2/HP1 and MET-2/SETDB1 bind distinct co-factors that promote heterochromatic foci, gene repression and organogenesis independently of H3K9 methylation
甘氨酰-tRNA隔离是GARS1相关周围神经病变的统一机制	Mora, N.	PDF	N/A	Glycyl-tRNA sequestration is a unifying mechanism underlying GARS1-associated peripheral neuropathy
一个共保守的基因对在螯合应激期间支持柄杆菌的铁稳态	Ortiz, S. H.	PDF	N/A	A co-conserved gene pair supports Caulobacter iron homeostasis during chelation stress
通过同时进行转录起始定位和甲基化定量来解码m6Am	Liu, J. F.	PDF	N/A	Decoding m6Am by simultaneous transcription-start mapping and methylation quantification
电休克疗法在小鼠和人类中引发了一波发作后的扩散性去极化波。	Rosenthal, Z.	PDF	N/A	Electroconvulsive therapy generates a postictal wave of spreading depolarization in mice and humans
靶向新生脂肪生成提高吉西他滨在胰腺导管腺癌中的疗效	Hancock, S. E.	PDF	N/A	Targeting de novo lipogenesis improves gemcitabine efficacy in pancreatic ductal adenocarcinoma
Citrobacter rodentium感染激活结肠固有层2型固有淋巴细胞	Berkachy, R.	PDF	N/A	Citrobacter rodentium infection activates colonic lamina propria group 2 innate lymphoid cells
食物搭配与西方和东方人群的饮食模式之外的心脏代谢特征独立相关	Deng, Q.	PDF	N/A	Food pairing independently associated with cardiometabolic traits beyond dietary patterns across western and eastern populations
行为与神经声音分类：从自然与合成声音中获得的洞见	Ogg, M.	PDF	N/A	Behavioral and neural sound classification: Insights from natural and synthetic sounds
海马-皮层连接与个体差异及在区分相似记忆中的训练收益相关	Iliopoulos, P.	PDF	N/A	Hippocampal-cortical connectivity relates to inter-individual differences and training gains in distinguishing similar memories
多巴胺和5-羟色胺在人类奖赏与惩罚过程中的不同作用：一项系统综述与荟萃分析	Mkrtchian, A.	PDF	N/A	Dopamine and serotonin differentially associated with reward and punishment processes in humans: A systematic review and meta-analysis
CAR T细胞工程影响抗原非依赖性激活和共抑制	Stuecheli, S.	PDF	N/A	CAR T cell engineering impacts antigen-independent activation and co-inhibition
MOSHPIT：基于QIIME 2框架的可访问、可重复的宏基因组数据科学	Ziemski, M.	PDF	N/A	MOSHPIT: accessible, reproducible metagenome data science on the QIIME 2 framework
家燕（Hirundo rustica）中的同种巢寄生现象	Jelinek, V.	PDF	N/A	Conspecific brood parasitism in the barn swallow (Hirundo rustica)
Neuropixels Opto：结合高分辨率电生理学与光遗传学	Lakunina, A.	PDF	N/A	Neuropixels Opto: Combining high-resolution electrophysiology and optogenetics
使用合成调控基因组学迭代改进深度学习模型	Ribeiro-dos-Santos, A. M.	PDF	N/A	Iterative improvement of deep learning models using synthetic regulatory genomics
评估参考基因组选择对分类学分析准确性的影响	van Bemmelen, J.	PDF	N/A	Benchmarking the impact of reference genome selection on taxonomic profiling accuracy
与EGFR突变非小细胞肺癌中靶向治疗出现耐药性相关的肿瘤微环境的空间动态变化	Nakamura, S.	PDF	N/A	Spatial dynamics of the tumor microenvironment associated with emerging resistance to targeted therapy in EGFR-mutated non-small cell lung cancer
大鼠在预定的阻力训练期间骨骼肌蛋白质组的适应性时间进程	Stead, C. A.	PDF	N/A	Adaptive time course of the skeletal muscle proteome during programmed resistance training in rats
饲料中添加的杆菌肽亚甲基二水杨酸酯以剂量依赖的方式改变了微生物群的功能，并增加了抗生素耐药性。	Oladele, P. O.	PDF	N/A	In-feed bacitracin methylene disalicylate alters microbiota function and increases antibiotic resistance in a dose-dependent manner
通过高分辨率质谱和计算机编程方法研究戈登氏菌（Gordonia rubropertincta）合成的色素的类胡萝卜素组学	Vemparala, G.	PDF	N/A	Caroten-omics of pigments synthesised by Gordonia rubropertincta through High Resolution Mass Spectrometry and in-silico programming approach
在空间设定转换过程中，背侧海马体在不同行为时间尺度上的节律性调节	Bottoms, M.	PDF	N/A	Rhythmic modulation of dorsal hippocampus across distinct behavioral timescales during spatial set-shifting
将“Cortical substrates of perceptual confusion between pitch and timbre”翻译成中文是：

“音高与音色感知混淆的皮层基础”

这个短语指的是研究大脑皮层在处理音高和音色时产生混淆的神经机制或基础。 | Ou, Y. | PDF | N/A | Cortical substrates of perceptual confusion between pitch and timbre | | 电耦合与H电流的功能性相互作用及其对抑制性传递的潜在影响 | Trigo, F. F. | PDF | N/A | Functional interaction of electrical coupling and H-current and its putative impact on inhibitory transmission | | 针对ClpP-α突触核蛋白相互作用，利用诱饵肽减轻帕金森病模型中的神经病理学变化 | Hu, D. | PDF | N/A | Targeting the ClpP-αSynuclein Interaction with a Decoy Peptide to Mitigate Neuropathology in Parkinson's Disease Models | | S-腺苷甲硫氨酸合成酶的功能特化将磷脂酰胆碱与线粒体功能和应激生存联系起来 | Munden, A. | PDF | N/A | Functional Specialization of S-Adenosylmethionine Synthases Links Phosphatidylcholine to Mitochondrial Function and Stress Survival | | 新型PINK1-Parkin线粒体自噬途径的报告基因揭示了其在输入门中的损伤传感器 | Thayer, J. A. | PDF | N/A | Novel reporter of the PINK1-Parkin mitophagy pathway identifies its damage sensor in the import gate | | β-羟基丁酸减轻支气管平滑肌促炎细胞因子的产生 | Fastiggi, V. A. | PDF | N/A | Beta-Hydroxybutyrate Attenuates Bronchial Smooth Muscle Pro-Inflammatory Cytokine Production | | Cloche/Npas4l 是斑马鱼心脏再生过程中的一种促再生血小板因子。 | Hou, J. | PDF | N/A | Cloche/Npas4l is a pro-regenerative platelet factor during zebrafish heart regeneration | | 在体内通过光笼化的磷酰二胺吗啉寡核苷酸实现mRNA翻译的光化学控制 | Tarbashevich, K. | PDF | N/A | Optochemical control over mRNA translation by photocaged phosphorodiamidate morpholino oligonucleotides in vivo | | 化学多样性促进生态系统功能 | Fonvielle, J. | PDF | N/A | Chemical diversity promotes ecosystem function | | 简化序贯抗生素疗法成功的计算平台 | Anderson, A. | PDF | N/A | Computational Platform for streamlining the success of sequential antibiotic therapy | | 基于基因的适应度模型及其对遗传变异的影响：遗传负荷与近交负荷 | Johri, P. | PDF | N/A | A gene-based model of fitness and its implications for genetic variation: Genetic and inbreeding loads | | 一系列功能失调的杂交表型加强了秀丽隐杆线虫（Caenorhabditis）物种之间的生殖隔离。 | Dall'Acqua, M. N. | PDF | N/A | A constellation of dysfunctional hybrid phenotypes enforces reproductive isolation between Caenorhabditis nematode species | | 热诱导的二次休眠有助于拟南芥的本地适应 | Tran, N. L. T. | PDF | N/A | Heat-induced secondary dormancy contributes to local adaptation in Arabidopsis thaliana | | 基于f4统计的祖先分析和卷积神经网络表型分析揭示了Aegilops tauschii Coss.遗传和穗形多样性的新结构。 | Koyama, Y. | PDF | N/A | f4-statistics-based ancestry profiling and convolutional neural network phenotyping shed new light on the structure of genetic and spike shape diversity in Aegilops tauschii Coss. | | 基于f4统计的祖先分析和卷积神经网络表型分析揭示了Aegilops tauschii Coss.遗传和穗形多样性的新结构。 | Koyama, Y. | PDF | N/A | f4-statistics-based ancestry profiling and convolutional neural network phenotyping shed new light on the structure of genetic and spike shape diversity in Aegilops tauschii Coss. | | 在非对称游戏中交友：绿猴中雌雄梳理行为的建立 | Tankink, J. A. | PDF | N/A | Making friends in an asymmetric game: the establishment of male-female grooming exchanges in vervet monkeys | | 简化的氨基酸替换矩阵揭示了现代蛋白质中古老编码字母的痕迹。 | Douglas, J. | PDF | N/A | Reduced amino acid substitution matrices find traces of ancient coding alphabets in modern day proteins | | 多组学网络方法揭示了先天性代谢缺陷的疾病修饰机制 | Bender, A. | PDF | N/A | A multiomic network approach uncovers disease modifying mechanisms of inborn errors of metabolism | | 进化上保守的分离酶在核纤层蛋白调控中的作用 | Cipressa, F. | PDF | N/A | An evolutionarily conserved role for separase in the regulation of nuclear lamins | | 使用基于Arduino的低成本可定制传感器进行跨上皮/内皮电测量 | Lattanzi, D. | PDF | N/A | Transepithelial/endothelial electrical measurement using a low-cost and customizable Arduino-based sensor | | 无鞘弹性惯性聚焦在直微通道中对25纳米以下粒子的应用 | Tanriverdi, S. | PDF | N/A | Sheathless elasto-inertial focusing of sub-25 nm particles in straight microchannels | | 探索光交联明胶的体积增材制造对间充质基质细胞行为和分化的影响 | Pien, N. | PDF | N/A | Exploring the Impact of Volumetric Additive Manufacturing of Photo-crosslinkable Gelatin on Mesenchymal Stromal Cell Behavior and Differentiation | | 在系统发育背景下测试相关演化的半参数方法 | Harmon, L. | PDF | N/A | A semiparametric method to test for correlated evolution in a phylogenetic context | | 通过同质嵌入方法进行RNA知识图谱分析 | Torgano, F. | PDF | N/A | RNA Knowledge-Graph analysis through homogeneous embedding methods | | TimeFlow: 一种基于密度的伪时间方法，用于流式细胞术数据分析 | Liarou, M. | PDF | N/A | TimeFlow: a density-driven pseudotime method for flowcytometry data analysis | | 迭代多尺度分子动力学：通过迭代全原子和粗粒度分子动力学模拟加速生物分子系统的构象采样 | Do, H. N. | PDF | N/A | Iterative Multiscale Molecular Dynamics: Accelerating Conformational Sampling of Biomolecular Systems by Iterating All-Atom and Coarse-Grained Molecular Dynamics Simulations | | 支气管血管束间充质基质细胞在排斥肺移植物中调控抗体分泌细胞生态位的特征研究 | McLinden, A. P. | PDF | N/A | Characterization of bronchovascular-bundle mesenchymal stromal cells regulating antibody-secreting cell niche in rejecting lung allografts | | 肾毒素和氧化剂对hiPSC来源的肾近端小管细胞存活和转运功能的影响 | Mboni-Johnston, I. M. | PDF | N/A | Impact of nephrotoxins and oxidants on survival and transport function of hiPSC-derived renal proximal tubular cells | | 神经元发育以刺激特异性的方式塑造活动依赖性基因表达。 | Lukin, J. | PDF | N/A | Neuronal development shapes activity-dependent gene expression in a stimulus-specific manner | | 小脑和皮层下结构对工作记忆操作的贡献 | Tan, J. B. C. | PDF | N/A | Cerebellar and Subcortical Contributions to Working Memory Manipulation | | 特定的神经母细胞衍生信号控制着前脑迁移流中的细胞迁移和命运。 | Zhou, W. | PDF | N/A | Specific neuroblast-derived signals control both cell migration and fate in the rostral migratory stream | | 叉头转录因子FKH-7/FOXP在化学感应神经元中发挥作用，以调节发育决策过程。 | Chai, C. M. | PDF | N/A | The forkhead transcription factor FKH-7/FOXP acts in chemosensory neurons to regulate developmental decision-making | | 大脑皮层中星形胶质细胞-突触相互作用的连接组学分析 | Yener, Y. | PDF | N/A | Connectomic analysis of astrocyte-synapse interactions in the cerebral cortex | | 从前额叶皮层活动的表征几何推断潜在行为策略 | Qian, Y. | PDF | N/A | Inferring Latent Behavioral Strategy from the Representational Geometry of Prefrontal Cortex Activity | | 利用扩散磁共振成像技术对大脑和脊髓中神经突和胞体的组织特性进行表征 | Schilling, K. | PDF | N/A | Characterization of neurite and soma organization in the brain and spinal cord with diffusion MRI | | 代谢纯化的人类干细胞衍生肝细胞揭示了埃博拉和拉沙病毒的不同影响 | Prescott, J. B. | PDF | N/A | Metabolically purified human stem cell-derived hepatocytes reveal distinct effects of Ebola and Lassa viruses | | Glyco-STORM：细胞糖基化景观的纳米级映射 | Schroeter, H. G. | PDF | N/A | Glyco-STORM: Nanoscale Mapping of the Cellular Glycosylation Landscape | | 教你的显微镜如何打印：面向生物学的低成本快速迭代微加工技术 | Hinderling, L. | PDF | N/A | Teach your microscope how to print: Low-cost and rapid-iteration microfabrication for biology | | 基于图像的检测分析中的替代染料 | Sivagurunathan, S. | PDF | N/A | Alternate dyes for image-based profiling assays | | 以两个调控元件为中心的激酶相互作用将检查点蛋白Lte1限制在芽细胞皮层区室中。 | Geymonat, M. | PDF | N/A | Kinase interplay centered on two regulatory elements confines the checkpoint protein Lte1 to the bud cell cortical compartment | | 将分子通路与人类1型糖尿病中的胰岛细胞功能障碍联系起来 | dos Santos, T. | PDF | N/A | Linking molecular pathways and islet cell dysfunction in human type 1 diabetes | | 细胞穿透肽介导的小鼠卵母细胞激活 | Suzuki, T. | PDF | N/A | Cell-penetrating peptide-mediated mouse oocyte activation | | 田间试验中连续施用植物保护产品对土壤微生物和自由生活线虫的影响 | Drocco, C. | PDF | N/A | Effects of a Sequential Application of Plant Protection Products on Soil Microbes and Free-Living Nematodes in a Field Experiment | | 以下是这段英文的中文翻译：

真核生物特异性DNA结合位点在阿斯加德古菌RecA重组酶中的进化

希望这个翻译对你有帮助！ | Ferlez, B. | PDF | N/A | Evolution of Eukaryotic Specific DNA Binding Sites in Asgard Archaeal RecA Recombinases | | 在雌性黑腹果蝇中，两次交配比单次交配会导致更多的交配伤害。 | Subasi, B. S. | PDF | N/A | Two matings lead to more copulatory wounding than a single mating in female Drosophila melanogaster | | 物种树分支长度估计，尽管存在不完全谱系分选、基因重复和丢失 | Tabatabaee, Y. | PDF | N/A | Species tree branch length estimation despite incomplete lineage sorting, duplication, and loss | | 细胞内竞争塑造质粒种群动态 | Rossine, F. | PDF | N/A | Intracellular competition shapes plasmid population dynamics | | 非平衡种群中背景选择模型 | Barroso, G. V. | PDF | N/A | A model for background selection in non-equilibrium populations | | 多基因适应性在基于网络衍生的性状下的遗传结构 | O'Brien, N. L. V. | PDF | N/A | The genetic architecture of polygenic adaptation under a network-derived trait | | 填补新热带区的空白：新发现的萤火虫物种为中美洲生物多样性提供洞见 | Catalan, A. | PDF | N/A | Filling the gap in the Neotropics: new firefly species provide insights into Central American biodiversity | | 生殖隔离机制之间的相互作用 | Blanckaert, A. | PDF | N/A | Interactions between mechanisms of reproductive isolation | | 了解使用人脑类器官微生理系统在阿尔茨海默病中单核细胞驱动的神经炎症 | Tian, C. | PDF | N/A | Understanding monocyte-driven neuroinflammation in Alzheimers disease using human brain organoid microphysiological systems | | 一个用于蛋白质-配体亲和力预测的基础模型，通过联合优化虚拟筛选和命中到先导化合物优化 | Feng, B. | PDF | N/A | A foundation model for protein-ligand affinity prediction through jointly optimizing virtual screening and hit-to-lead optimization | | 提高从基因调控网络的时间序列数据中推断相互作用的可靠性。 | Greco, M. | PDF | N/A | Boosting reliability when inferring interactions from time series data in gene regulatory networks. | | 神经物理自适应重建技术揭示了大景深范围内的三维亚细胞纳米结构。 | Fu, S. | PDF | N/A | Neural-physics adaptive reconstruction reveals 3D subcellular nanostructures over a large depth of field | | 银屑病中的T细胞特异性miRNA-靶点网络：一项系统性综述 | Jain, M. | PDF | N/A | The T Cell-Specific miRNA-Target Network in Psoriasis: A Systematic Review | | 在一个已建立的类风湿性关节炎队列中，对CD4 Th亚群的特征以及饮食、运动和生活方式因素的表征；初步研究。 | Venkataraman, S. | PDF | N/A | Characterisation of CD4 Th subsets as well as dietary, exercise and lifestyle factors in an established Rheumatoid Arthritis cohort; pilot study. | | 针对体外候选基因的敲低不会改变体内沃尔巴克氏体的密度。 | Dainty, K. R. | PDF | N/A | Targeted knockdown of in vitro candidates does not alter Wolbachia density in vivo | | 在自噬缺陷条件下，KEAP1滞留在相分离的p62小体中导致肝脏损伤。 | Komatsu, M. | PDF | N/A | KEAP1 retention in phase-separated p62 bodies drives liver damage in autophagy-deficient conditions | | 果蝇对胆固醇味道的回避 | Nhuchhen Pradhan, R. | PDF | N/A | Cholesterol taste avoidance in Drosophila melanogaster | | RAB23通过促进RAB18介导的BBSome向内转运通过过渡区来调节信号蛋白纤毛稳态 | Sun, S.-N. | PDF | N/A | RAB23 Modulates Signaling Protein Ciliary Homeostasis through Promoting RAB18-mediated Inward BBSome Transition Zone Passage | | Dora是目标导向的miRNA降解的关键组成部分，对于果蝇卵巢滤泡细胞中的局部基因组扩增至关重要。 | Akulenko, N. | PDF | N/A | Dora, a key component of target-directed miRNA degradation, is essential for local genomic amplification in Drosophila ovarian follicle cells | | 在新生隐球菌（Cryptococcus deneoformans）中，钙调磷酸酶（Calcineurin）在热应激期间控制细胞分裂机制。 | Yadav, V. | PDF | N/A | Calcineurin controls the cytokinesis machinery during thermal stress in Cryptococcus deneoformans | | 冬季蜱（Dermacentor albipictus）的转录组分析揭示了性别特异性表达模式 | Edwards, R. T. M. | PDF | N/A | Transcriptome analysis of the winter tick (Dermacentor albipictus) reveals sex-specific expression patterns | | 年龄相关的抑制功能下降：探究抑制子成分及其对健康老龄化中持续注意力的影响 | Treacy, C. | PDF | N/A | Age-related Inhibitory Decline: Examining Inhibition Sub-Components and their Impact on Sustained Attention in Healthy Ageing | | 使用centroAnno进行着丝粒的从头注释 | qi, j. | PDF | N/A | De novo annotation of centromere with centroAnno | | 成人短期单眼剥夺：一项荟萃分析与新视角 | Steinwurzel, C. | PDF | N/A | Short-term monocular deprivation in adult humans: a meta-analysis and new perspectives | | 贝叶斯整合在代理感中的应用：理解自我归因与个体差异 | Chang, A. Y.-C. | PDF | N/A | Bayesian Integration in Sense of Agency: Understanding Self-attribution and Individual Differences | | L-精氨酸和非对称二甲基精氨酸（ADMA）在血脑屏障和血脑脊液屏障中的转运蛋白饱和动力学及特异性研究。 | Fidanboylu, M. | PDF | N/A | Saturation kinetics and specificity of transporters for L-arginine and asymmetric dimethylarginine (ADMA) at the blood-brain and blood-CSF barriers. | | 中国自闭症脑成像联盟：绘制中国自闭症儿童大脑发育图谱 | Li, L. | PDF | N/A | China Autism Brain Imaging Consortium: Charting Brain Growth in Chinese Children with Autism | | COVID-19急性后遗症的免疫学和临床标志物：感染后六个月的轻症和重症病例的见解 | Mouton, W. | PDF | N/A | Immunological and clinical markers of post-acute sequelae of COVID-19: Insights from mild and severe cases six months post-infection | | 研究水泥基表面作为一种可持续的地板解决方案，以提高在资源匮乏环境中蛔虫卵的去除和灭活效果 | Anderson, C. | PDF | N/A | Investigating Cement-Based Surfaces as a Sustainable Flooring Solution to Improve Ascaris Egg Removal and Inactivation in Low-Resource Settings | | 持续的关节感染和宿主反应性反应导致了SKG小鼠中布鲁氏菌诱导的脊柱关节炎。 | Harms, J. | PDF | N/A | Persistent articular infection and host reactive response contribute to Brucella-induced spondyloarthritis in SKG mice | | 一项旨在识别抗真菌拮抗剂的筛选研究发现，多种药物治疗方法会诱导白色念珠菌对棘白菌素类药物产生耐受性。 | Reitler, P. | PDF | N/A | A screen to identify antifungal antagonists reveals a variety of pharmacotherapies induce echinocandin tolerance in Candida albicans. | | 各向同性、像差校正的光片显微镜用于快速高分辨率成像的透明组织 | Aakhte, M. | PDF | N/A | Isotropic, aberration-corrected light sheet microscopy for rapid high-resolution imaging of cleared tissue | | 人类大脑皮层在出生前和出生后的细胞类型特异性DNA甲基化动态变化 | Franklin, A. | PDF | N/A | Cell-type-specific DNA methylation dynamics in the prenatal and postnatal human cortex | | 理性设计的PKD1激活剂在帕金森病临床前模型中保护神经退行性变 | Asaithambi, A. | PDF | N/A | Rationally Designed PKD1 Activator Protects Against Neurodegeneration in Pre-clinical Models of Parkinson's Disease | | 肿瘤细胞的暂时性挑战可能导致记忆CD8 T细胞功能的永久性部分损伤。 | Laubreton, D. | PDF | N/A | A temporary challenge by tumor cells can lead to a permanent partial-impairment of memory CD8 T cell function | | 人乳来源的细胞外囊泡治疗促进围产期高脂饮食暴露新生儿的热休克反应。 | Storm, J. A. | PDF | N/A | Human milk-derived extracellular vesicle treatment promotes the heat shock response in neonates with perinatal high fat diet exposure. | | 中性粒细胞来源的微囊泡诱导与动脉粥样硬化斑块侵蚀相关的内皮细胞功能障碍。 | Dow, R. | PDF | N/A | Neutrophil derived microvesicles induce endothelial cell dysfunction associated with atherosclerotic plaque erosion. | | 差异化的AXL表达和Arf1的调控控制着乳腺癌细胞中基质硬度依赖的高尔基体组织和功能。 | Saha, A. | PDF | N/A | Differential AXL expression and regulation of Arf1 controls matrix stiffness-dependent Golgi organization and function in breast cancer cells | | 肌动蛋白收缩性和内吞作用在HeLa细胞中形成了顶端-基底张力梯度 | Ghosh, T. | PDF | N/A | Actin contractility and endocytosis create apico-basal tension gradient in HeLa cells | | 研究Blebbistatin对肌原纤维和分离肌丝中肌动球蛋白相互作用的抑制作用 | Elkrief, D. | PDF | N/A | INVESTIGATING THE INHIBITORY EFFECTS OF BLEBBISTATIN ON ACTOMYOSIN INTERACTIONS IN MYOFIBRILS AND ISOLATED MYOFILAMENTS | | Ist2/Osh6复合物在膜接触位点进行脂质运输的结构基础 | Arndt, M. | PDF | N/A | Structural basis for lipid transport at membrane contact sites by the Ist2/Osh6 complex | | 与胎儿水肿相关的单残基突变L322P消除了PIEZO1离子通道的机械激活，但不影响其化学激活。 | Jiang, J. | PDF | N/A | The fetal hydrops-associated single-residue mutation L322P abolishes mechanical but not chemical activation of the PIEZO1 ion channel | | FMRP调控含有停滞核糖体的神经元RNA颗粒，而非核糖体停滞的位置 | Li, J. T.-Y. | PDF | N/A | FMRP Regulates Neuronal RNA Granules Containing Stalled Ribosomes, Not Where Ribosomes Stall | | EpiMolBio：一款用于遗传变异分析的新型用户友好型生物信息学程序 | Reinosa, R. | PDF | N/A | EpiMolBio: A Novel User-Friendly Bioinformatic Program for Genetic Variability Analysis | | 米非司酮单独使用及与scAAV9-SMN1基因治疗联合使用可改善Smn2B/-脊髓性肌萎缩症小鼠的疾病表型 | Sutton, E. R. | PDF | N/A | Mifepristone alone and in combination with scAAV9-SMN1 gene therapy improves disease phenotypes in Smn2B/- spinal muscular atrophy mice | | 标题：利用合成复制起点工程化质粒 | Liu, B. | PDF | N/A | Title: Engineering Plasmids with Synthetic Origins of Replication | | 布鲁氏锥虫在牛体内的感染中，在低寄生虫血症时存在隐性的适应传播的血流形式。 | Larcombe, S. D. | PDF | N/A | Trypanosoma brucei cattle infections contain cryptic transmission-adapted bloodstream forms at low parasitaemia | | 针对2.3.4.4b分支H5N1血凝素的人源单克隆抗体 | Pena Alzua, G. | PDF | N/A | Human monoclonal antibodies that target clade 2.3.4.4b H5N1 hemagglutinin | | 以下是这段英文的中文翻译：

自然感染松材线虫（Bursaphelenchus xylophilus）的海岸松（Pinus pinaster）树木的菌群组

翻译说明： - "Mycobiome" 翻译为“菌群组”，指的是真菌群落的集合。 - "Pinus pinaster" 是植物学名，中文名为“海岸松”或“海松”。 - "pinewood nematode" 翻译为“松材线虫”，是一种危害松树的病原线虫。 - "Bursaphelenchus xylophilus" 是松材线虫的学名，直接保留原文。

本研究探讨了无环核苷膦酸酯前药LAVR-289在体外（实验室条件下）和体内（活体动物模型中）对痘病毒（Poxvirus）及非洲猪瘟病毒（African Swine Fever Virus, ASFV）复制的抑制效果。研究结果表明，LAVR-289在两种实验条件下均展现出显著的抗病毒活性，能够有效抑制上述病毒的复制过程。这一发现为开发针对痘病毒和非洲猪瘟病毒的新型抗病毒药物提供了重要的实验依据。 | Marcheteau, E. | PDF | N/A | In vitro and in vivo Antiviral Activity of the Acyclic Nucleoside Phosphonate Prodrug LAVR-289 against Poxvirus and African Swine Fever Virus Replication | | 综合DNA相互作用组和转录组分析揭示了PU.1/增强子RNA介导的前馈调控环路在单核细胞/巨噬细胞发育和先天免疫功能中的调控作用 | Waliullah, A. | PDF | N/A | An integrated DNA interactome and transcriptome profiling reveals a PU.1/enhancer RNA-mediated Feed-forward Regulatory Loop Regulating monocyte/macrophage development and innate immune functions | | 比目鱼变态过程中的表观遗传调控：基于DNA甲基化和基因表达整合组学分析的比目鱼脑研究 | Guerrero-Pena, L. | PDF | N/A | Epigenetic Regulation During Flatfish Metamorphosis: Integrative Omics Analysis of DNA Methylation and Gene Expression in Turbot Brain | | 一种利用荧光标记DNA寡核苷酸检测Cas9 gRNA的新方法 | Bandara, R. A. | PDF | N/A | A novel method for detection of Cas9 gRNAs using a fluorophore-labeled DNA oligo | | 阿尔茨海默病AppNL-G-F敲入小鼠模型中，海马区的表观遗传和转录组学改变先于淀粉样蛋白沉积发生 | Okhovat, M. | PDF | N/A | Epigenetic and Transcriptomic Alterations Precede Amyloidosis in the Hippocampus of the Alzheimer's Disease AppNL-G-F Knock in Mouse Model | | 在人工林中，鸟类的出现和营养相互作用随着树木多样性和小气候的梯度变化而变化。 | Coyne, S. | PDF | N/A | Bird occurrence and trophic interactions vary across gradients of tree diversity and microclimate in a planted forest | | DAF-18/PTEN 保护 LIN-35/Rb 免受 CLP-1/CAPN 介导的切割，从而促进抗饥饿能力 | Chen, J. | PDF | N/A | DAF-18/PTEN protects LIN-35/Rb from CLP-1/CAPN-mediated cleavage to promote starvation resistance | | SpaFun：利用功能主成分分析发现特定领域的空间表达模式及新的疾病相关基因 | Jiang, X. | PDF | N/A | SpaFun: Discovering Domain-specific Spatial Expression Patterns and New Disease-Relevant Genes using Functional Principal Component Analysis | | 通用直系同源物推断深层系统发育关系并提升基因组质量评估 | Alam, M. N. U. | PDF | N/A | Universal orthologs infer deep phylogenies and improve genome quality assessments | | 使用Evo 2进行跨生命领域的基因组建模与设计 | Brixi, G. | PDF | N/A | Genome modeling and design across all domains of life with Evo 2 | | 化学抑制细菌免疫系统 | Zang, Z. | PDF | N/A | Chemical inhibition of a bacterial immune system | | 通过使用CRISPR-Cas9技术敲除组氨酸氨裂解酶，消除了组氨酸在克氏锥虫生物能量学和生命周期中的作用。 | De Freitas Nascimento, J. | PDF | N/A | Knocking out histidine ammonia-lyase by using CRISPR-Cas9 abolishes histidine role in the bioenergetics and the life cycle of Trypanosoma cruzi. | | 优化在大肠杆菌中生产Ramonda serbica LEA蛋白及其二级结构分析 | Pantelic, A. | PDF | N/A | Optimisation of Ramonda serbica LEA protein production in Escherichia coli and its secondary structure analysis | | 基于代理的细胞动力学建模在过继性细胞治疗中的应用 | Wang, Y. | PDF | N/A | Agent-based modeling of cellular dynamics in adoptive cell therapy | | 宏基因组分箱评估：进展与挑战 | Arangasamy, Y. | PDF | N/A | Evaluation of Metagenome Binning: Advances and Challenges | | NRGRank：基于粗粒度结构信息的超大规模虚拟筛选 | DesCoteaux, T. | PDF | N/A | NRGRank: Coarse-grained structurally-informed ultra-massive virtual screening | | 使用核张力传感器剖析SUN蛋白间的力传递 | Wang, J. | PDF | N/A | Dissecting Force Transmission across SUN Proteins Using Nuclear Tension Sensors | | AlphaFold 作为先验：基于预训练神经网络的实验结构确定 | Fadini, A. | PDF | N/A | AlphaFold as a Prior: Experimental StructureDetermination Conditioned on a Pretrained Neural Network | | 环境相关铅暴露改变SH-SY5Y神经元分化过程中的细胞形态和神经标志物表达 | Morgan, R. K. | PDF | N/A | Environmentally Relevant Lead Exposure Alters Cell Morphology and Expression of Neural Hallmarks During SH-SY5Y Neuronal Differentiation | | 通过表达野生型MeCP2或使用G418进行读通，可以改善R255X MECP2敲入小鼠皮质神经元的体外细胞表型。 | Xu, X. | PDF | N/A | In vitro cellular phenotypes of cortical neurons from R255X MECP2 knock-in mice are improved by either expression of wildtype MeCP2 or read-through with G418 | | JAK抑制剂通过消除先天免疫屏障来促进病毒传播 | Ravlo, E. | PDF | N/A | JAK inhibitors remove innate immune barriers to allow viral propagation | | RNA引导的核酸酶能够在质粒中实现插入序列的基因驱动。 | Mears, K. | PDF | N/A | RNA-guided nucleases enable a gene drive of insertion sequences in plasmids | | RB-TnSeq揭示了β-变形菌中二羧酸特异性分解代谢机制，以提升塑料单体升级回收效率。 | Pearson, A. N. | PDF | N/A | RB-TnSeq elucidates dicarboxylic acid specific catabolism in β-proteobacteria for improved plastic monomer upcycling | | 研究ORF150的E3泛素连接酶活性在鱼类疱疹病毒发病机制中的作用 | Wang, H. | PDF | N/A | Investigating E3 ubiquitin ligase activity of ORF150 in fish herpesvirus pathogenesis | | 以下是这段英文的中文翻译：

关于SOD1催化过程中水分子动力学及其与药物相互作用的结构性洞察

翻译说明： - "Structural Insights" 译为 "结构性洞察"，指通过结构分析获得的深入理解。 - "Dynamics of Water" 译为 "水分子的动力学"，强调水分子的运动和作用。 - "SOD1 Catalysis" 译为 "SOD1催化过程"，SOD1是一种超氧化物歧化酶，参与催化反应。 - "Drug Interactions" 译为 "药物相互作用"，指药物与SOD1之间的相互影响。