BioRxiv 2025-02-23 Papers
| 标题 | 作者 | PDF链接 | 代码仓库 | Title |
|---|---|---|---|---|
| 基于点击化学的大肠杆菌分子积累测定 | Ongwae, G. M. | N/A | Click-Based Determination of Accumulation of Molecules in Escherichia coli | |
| 人类iPSC衍生心肌细胞中细丝的结构及其对心脏病的反应 | Woldeyes, R. A. | N/A | Structure of the Thin Filament in Human iPSC-derived Cardiomyocytes and its Response to Heart Disease | |
| 在宿主范围扩大和毒力增强过程中，沙门氏菌噬菌体的趋同进化 | Maurin, A. | N/A | Convergent evolution during host range expansion and virulence increase in a Salmonella bacteriophage | |
| 转录因子的基础结合有利于早期基因表达 | Pinheiro, S. | N/A | Basal association of a transcription factor favors early gene expression | |
| 小岛种群对于濒危大型岛屿哺乳动物长期生存的重要性 | Aninta, S. G. | N/A | The importance of small island populations for the long term survival of endangered large-bodied insular mammals | |
| 对CrHCF244的研究揭示了莱茵衣藻（Chlamydomonas reinhardtii）和拟南芥（Arabidopsis thaliana）在psbA翻译过程中的相似性和差异性。 | Wang, X. | N/A | Studies of CrHCF244 reveal similarities and differences in psbA translation between Chlamydomonas reinhardtii and Arabidopsis thaliana | |
| 以下是这段英文的中文翻译： |
"水蚤（Daphnia magna）全基因组DNA甲基化模式与年龄无显著关联"
翻译说明： 1. "Genome-wide" 翻译为 "全基因组"，表示研究范围覆盖整个基因组。 2. "DNA Methylation Patterns" 翻译为 "DNA甲基化模式"，指的是DNA分子上甲基化修饰的分布和特征。 3. "Daphnia magna" 是水蚤的学名，直接保留拉丁学名，并在括号中注明中文名。 4. "are Not Significantly Associated with" 翻译为 "无显著关联"，表示统计学上没有显著的相关性。 5. "Age" 翻译为 "年龄"，指的是生物体的生命周期阶段。
这个标题表明了一项研究结果，即在水蚤中，全基因组范围内的DNA甲基化模式与年龄之间没有显著的统计学关联。 | Liu, R. | PDF | N/A | Genome-wide DNA Methylation Patterns in Daphnia magna are Not Significantly Associated with Age | | 以下是这段英文的中文翻译：
基因组洞察纪念玫瑰（Rosa lucieae；蔷薇科）在盐环境中的适应性进化
这段文字描述了一项关于纪念玫瑰（Rosa lucieae）在盐环境中适应性进化的基因组研究。研究通过基因组分析，揭示了该植物如何在盐胁迫条件下进行适应性进化。 | Jeon, J.-H. | PDF | N/A | Genomic insights into the adaptive evolution of the memorial rose (Rosa lucieae; Rosaceae) in saline environments | | 儿童早期大脑皮层区域划分的普遍性研究 | Tu, J. | PDF | N/A | The Generalizability of Cortical Area Parcellations Across Early Childhood | | 一种数据驱动算法用于确定1H-MRS基础集组成 | Davies-Jenkins, C. W. | PDF | N/A | A data-driven algorithm to determine 1H-MRS basis set composition | | 通过可编程熵实现平衡状态下的分子计算 | Wang, B. | PDF | N/A | Molecular computation at equilibrium via programmable entropy | | 淀粉样前体蛋白在短寿命的绿松石鳉鱼（Nothobranchius furzeri）中促进大脑老化和学习能力下降 | de Bakker, D. E. M. | PDF | N/A | Amyloid beta precursor protein contributes to brain aging and learning decline in short-lived turquoise killifish (Nothobranchius furzeri) | | 产卵抑制神经元是果蝇大脑中多回路集成的潜在枢纽。 | Weber-Langstaff, R. A. | PDF | N/A | The Oviposition Inhibitory Neuron is a potential hub of multi-circuit integration in the Drosophila brain | | 将结构表示蒸馏到蛋白质序列模型中 | Ouyang-Zhang, J. | PDF | N/A | Distilling structural representations into protein sequence models | | 使用12-6 Lennard-Jones势能模型模拟银(I)离子与蛋白质的相互作用：一种自下而上的参数化方法 | Manciocchi, L. | PDF | N/A | Modelling the interaction between silver(I) ion and proteins with the 12-6 Lennard-Jones potential: a bottom-up parameterization approach | | 在一种常见的大规模产卵珊瑚中，异步产卵与混合繁殖策略 | Ricardo, G. F. | PDF | N/A | Spawning asynchrony and mixed reproductive strategies in a common mass spawning coral | | 基于结构的嵌合流感血凝素设计以引发跨组免疫 | Castro, K. M. | PDF | N/A | Structure-based Design of Chimeric Influenza Hemagglutinins to Elicit Cross-group Immunity | | 在1型糖尿病的发病机制中，β细胞功能障碍的发生与胰岛炎无关。 | Huber, M. K. | PDF | N/A | Beta cell dysfunction occurs independently of insulitis in type 1 diabetes pathogenesis | | CellFateExplorer：一个用于探索细胞命运的集成平台 | Huang, Z. | PDF | N/A | CellFateExplorer: An integrated platform for exploring cell fate | | 使用图变换器和成对相似性图估计蛋白质复合物模型的准确性 | Liu, J. | PDF | N/A | Estimating Protein Complex Model Accuracy Using Graph Transformers and Pairwise Similarity Graphs | | ABCG1转运蛋白有助于地钱（Marchantia polymorpha）油体中倍半萜的积累。 | Forestier, E. C. F. | PDF | N/A | The ABCG1 transporter facilitates sesquiterpene accumulation in Marchantia polymorpha oil bodies. | | 不同调节性T细胞亚群在结直肠癌中的相反功能 | Huang, X. | PDF | N/A | Opposing Functions of Distinct Regulatory T Cell Subsets in Colorectal Cancer | | 跨竞争性动作的一致神经元调制挑战了黑质在动作选择中的作用。 | Hou, L. | PDF | N/A | Congruent neuronal modulation across competing actions challenges the role of the substantia nigra in action selection | | 人类海马体语义的向量编码 | Franch, M. | PDF | N/A | A vectorial code for semantics in human hippocampus | | 皮质脊髓束损伤后的反射亢进反映了1A传入神经回路的变化，而非KCC2过度兴奋性的增加。 | Bethea, T. | PDF | N/A | Hyperreflexia after corticospinal tract lesion reflects 1A afferent circuit changes not increased KCC2 hyperexcitability | | 在神经系统发育过程中，集群突触的出现 | Balshayi, Y. | PDF | N/A | Emergence of clustered synapses during the development of a nervous system | | 视交叉上核神经介素-S神经元调节觉醒 | Wu, Y. | PDF | N/A | Suprachiasmatic Neuromedin-S Neurons Regulate Arousal | | 克隆干扰、遗传变异与结构化种群中的进化速度 | Ping Kuo, Y. | PDF | N/A | Clonal interference, genetic variation and the speed of evolution in structured populations | | EPIraction - 人类组织和细胞系中候选增强子-基因相互作用的图谱。 | Nurtdinov, R. | PDF | N/A | EPIraction - an atlas of candidate enhancer-gene interactions in human tissues and cell lines. | | 多构象肽离子的碰撞截面预测与IM2Deep | Devreese, R. | PDF | N/A | Collisional cross-section prediction for multiconformational peptide ions with IM2Deep | | 《柳叶刀》2：通过联合多样本局部组装图改进并加速体细胞变异检测 | Musunuri, R. L. | PDF | N/A | Lancet2: Improved and accelerated somatic variant calling with joint multi-sample local assembly graph | | 《柳叶刀》2：通过联合多样本局部组装图改进并加速体细胞变异检测 | Musunuri, R. L. | PDF | N/A | Lancet2: Improved and accelerated somatic variant calling with joint multi-sample local assembly graph | | 解码金黄色葡萄球菌中的宿主-病原体相互作用：基于人工智能和机器学习方法的等位基因变异与抗菌素耐药性预测的见解 | Ghosh, J. | PDF | N/A | Decoding Host-Pathogen Interactions in Staphylococcus aureus: Insights into Allelic Variation and Antimicrobial Resistance Prediction Using Artificial Intelligence and Machine Learning based approaches | | C.La.P.：通过整合DNA序列和染色质可及性数据增强基于Transformer的基因组信号建模 | Firbas Nisantzis, P. | PDF | N/A | C.La.P.: Enhancing transformer-based genomic signal modeling by integrating DNA sequences and chromatin accessibility data | | 在适应低氧水平过程中淋球菌的极化动力学 | Schiefer, P. | PDF | N/A | Gonococcal polarization dynamics during adaptation to low oxygen levels | | PLK4抑制作为增强非小细胞肺癌放射敏感性的一种策略 | Dominguez-Vigil, I. G. | PDF | N/A | PLK4 inhibition as a strategy to enhance non-small cell lung cancer radiosensitivity | | 人工智能辅助的透射电子显微镜图像自动分析用于评估化疗对三阴性乳腺癌线粒体形态的影响 | Arriojas, A. | PDF | N/A | Artificial intelligence-enabled automated analysis of transmission electron micrographs to evaluate chemotherapy impact on mitochondrial morphology in triple negative breast cancer | | 杜氏肌营养不良症DE50-MD狗模型的临床前心脏表型。 | Sargent, J. | PDF | N/A | The preclinical cardiac phenotype of the DE50-MD dog model of Duchenne muscular dystrophy. | | 混合神经网络在自主运动中的应用 | Mao, H. | PDF | N/A | Hybrid Neural Networks for Volitional Movement | | 以下是这段英文的中文翻译：
气味诱发的呼吸反应在正常视力小鼠和失明小鼠的整个发育过程中的表现
或者更简洁地表达为：
正常视力与失明小鼠发育过程中气味诱发的呼吸反应
具体翻译可以根据上下文调整，但核心意思是研究正常视力和失明小鼠在不同发育阶段对气味的呼吸反应。 | Bouguiyoud, N. | PDF | N/A | Odor-evoked respiratory responses throughout development in sighted and blind mice | | 围产期环境丰富性影响小鼠新生儿在主动参与环境前的大脑结构。 | Kaller, M. S. | PDF | N/A | Perinatal environmental enrichment affects murine neonates' brain structure before their active engagement with environment | | 基于机器学习的行为分析模型在啮齿动物中的应用：以强迫游泳测试为例 | Della Valle, A. | PDF | N/A | Machine Learning-Based Model for Behavioral Analysis in Rodents: Application to the Forced Swim Test | | 预测连续θ爆发刺激对神经可塑性的影响：基于运动诱发电位TMS输入-输出曲线的生物标志物 | Parchure, S. | PDF | N/A | Predicting Neuroplasticity Effects of Continuous Theta Burst Stimulation with Biomarkers from the Motor Evoked Potential TMS Input-Output Curve | | 用于OPM-MEG的双平面消磁线圈系统，采用印刷电路板 | Jas, M. | PDF | N/A | Biplanar nulling coil system for OPM-MEG using printed circuit boards | | 物体表征驱动着跨越大量多样化日常生活场景的情绪图式。 | Gao, C. | PDF | N/A | Object representations drive emotion schemas across a large and diverse set of daily-life scenes | | 大型语言模型中的涌现模块化：来自失语症模拟的洞见 | Wang, C. | PDF | N/A | Emergent modularity in large language models: Insights from aphasia simulations | | ASH1L基因突变导致一种神经发育障碍，该障碍在癫痫和自闭症方面表现出性别差异。 | Papendorp, C. M. | PDF | N/A | Mutations in ASH1L cause a neurodevelopmental disorder with sex differences in epilepsy and autism | | 结核病肉芽肿的免疫代谢地形决定了细胞组织和细菌控制。 | McCaffrey, E. F. | PDF | N/A | The immunometabolic topography of tuberculosis granulomas governs cellular organization and bacterial control | | GATA2在动脉粥样硬化过程中介导巨噬细胞增殖 | Aktar, A. | PDF | N/A | GATA2 Mediates Macrophage Proliferation During Atherosclerosis | | RNase J参与蓝藻中CRISPR RNA的成熟和降解体形成 | Bilger, R. | PDF | N/A | Involvement of RNase J in CRISPR RNA maturation and degradosome formation in cyanobacteria | | 裂殖酵母端粒酶RNA：二级结构与柔性支架功能 | McMurdie, K. | PDF | N/A | S. pombe telomerase RNA: secondary structure and flexible-scaffold function | | 利用非洲爪蟾受精卵中的细胞质RNA快速组装原核 | Ikeda, M. | PDF | N/A | Rapid pronucleus assembly using cytoplasmic RNAs in fertilized eggs of Xenopus laevis | | 《表观遗传调控在比目鱼变态期间视觉系统重塑中的作用：眼迁移和视觉适应中的DNA甲基化动态》 | Guerrero-Pena, L. | PDF | N/A | Epigenetic Regulation of Visual System Remodeling During Flatfish Metamorphosis: DNA Methylation Dynamics in Ocular Migration and Visual Adaptation | | 在突变和波动稳定选择之间的平衡下，定量遗传变异的强烈放大 | Bertram, J. | PDF | N/A | Strong amplification of quantitative genetic variation under a balance between mutation and fluctuating stabilizing selection | | 社会环境和多巴胺信号在蘑菇体中汇聚，共同驱动冲动行为。 | Sabandal, P. R. | PDF | N/A | Social context and dopamine signaling converge in the mushroom body to drive impulsivity | | 机器学习集成识别出乳腺组织对太空飞行的不同年龄相关反应 | Casaletto, J. A. | PDF | N/A | Machine learning ensemble identifies distinct age-related response to spaceflight in mammary tissue | | CombDNF：基于网络特征的疾病特异性药物组合预测——基于临床验证数据 | Hiort, P. | PDF | N/A | CombDNF: Disease-specific drug combination predictions with network-based features on clinically validated data | | 长期综合养分管理措施对土壤细菌多样性的影响：基于16S rRNA的宏基因组学方法
这段文字描述了一项研究，旨在探讨长期综合养分管理措施对土壤细菌多样性的影响。研究采用了基于16S rRNA的宏基因组学方法，这是一种通过分析细菌16S rRNA基因序列来评估微生物群落多样性和结构的技术。通过这种方法，研究人员能够深入了解不同养分管理措施对土壤微生物群落的影响，从而为可持续农业实践提供科学依据。 | Ahlawat, V. | PDF | N/A | Impact of Long-Term Integrated Nutrient Management Practices on Soil Bacterial Diversity: A 16S rRNA-Based Metagenomic Approach | | 热休克应激下的动态脂质组重组 | Solano, L. E. | PDF | N/A | Dynamic Lipidome Reorganization in Response to Heat Shock Stress | | 通过比较基因组分析，在卵菌纲中保守和发现调控基序 | Bharti, S. | PDF | N/A | Conservation and discovery of regulatory motifs across oomycetes through comparative genomic analysis | | BENDER DB：一个涵盖被忽视疾病蛋白质组的蛋白质结合位点数据库 | Paiva, V. | PDF | N/A | BENDER DB: a database of protein binding sites across neglected disease proteomes | | pMHC包被纳米颗粒的几何形状和T细胞受体簇的分布决定了T细胞反应中敏感性与特异性之间的权衡关系。 | Richez, L. | PDF | N/A | The geometry of pMHC-coated nanoparticles and T cell receptor clusters governs the sensitivity-specificity trade-off in T cell response. | | 利用粗粒化模拟研究植物类囊体膜中叶绿素聚集和光捕获复合体II的动态无序性 | Saini, R. | PDF | N/A | Dynamic Disorder in Chlorophyll Aggregation and Light-Harvesting Complex II in the Plant Thylakoid Membrane using Coarse-Grained Simulations | | ABL激酶调节转移性三阴性乳腺癌中EZH2的磷酸化和信号传导 | Colemon, A. | PDF | N/A | ABL Kinases Modulate EZH2 Phosphorylation and Signaling in Metastatic Triple Negative Breast Cancer | | 使用光亲和探针在动物模型和人类组织中发现的芬太尼非阿片受体蛋白靶点 | Lin, V. S. | PDF | N/A | Discovery of non-opioid receptor protein targets of fentanyl across tissues from animal models and humans using photoaffinity probes | | 增强C/EBPα功能可延长非洲青鳉鱼的健康寿命和寿命 | Muller, C. | PDF | N/A | Enhanced C/EBPα function extends healthspan and lifespan in the African turquoise killifish | | 光周期解码器1通过生长激素信号通路调节能量代谢的季节性变化。 | Nakayama, T. | PDF | N/A | Photoperiod decoder 1 regulates seasonal changes in energy metabolism through the growth hormone signaling pathway | | 三倍体在浮萍科植物小浮萍（Lemna minor）复合体中非常显著。 | Michael, T. P. | PDF | N/A | Triploidy is prominent in the duckweed Lemna minor complex | | mRNA m6A 写入复合物的破坏在拟南芥中引发自身免疫反应 | Metheringham, C. L. | PDF | N/A | Disruption of the mRNA m6A writer complex triggers autoimmunity in Arabidopsis | | 光敏色素相互作用因子在拟南芥顶端钩开口过程中协调微管动力学和差异细胞生长是必需的。 | Burachik, N. | PDF | N/A | PHYTOCHROME INTERACTING FACTORS are required to coordinate microtubule dynamics and differential cell growth during Arabidopsis apical hook opening | | 'SpikeNburst' 和 'Nicespike'：用于增强和加速体外高密度电生理学分析的高级工具 | Wolff, R. | PDF | N/A | 'SpikeNburst' and 'Nicespike': Advanced Tools for Enhancing and Accelerating In Vitro High-Density Electrophysiology Analysis | | 通过一种新型小分子TrkB激活剂长期功能性挽救创伤性视力丧失 | Modgil, S. | PDF | N/A | Long-Term Functional Rescue of Trauma-Induced Vision Loss by a Novel, Small Molecule TrkB Activator | | 利用与非核糖体肽合成酶（NRPS）和多酮合酶（PKS）编码基因相关的致病性对水稻进行Cochliobolus miyabeanus物种特异性鉴定 | Mohd Zainudin, N. A. I. | PDF | N/A | Cochliobolus miyabeanus species-specific identification using nonribosomal peptide synthetase (NRPS) and polyketide synthase (PKS)-encoding genes associated with virulence to rice | | 基因组范围内由活性氧诱导的5'-醛基末端定位 | Wu, J. | PDF | N/A | Genome-wide mapping of 5'-aldehyde terminus induced by reactive oxygen species | | 长期睡眠不足通过激活小鼠体内的补体和凝血级联反应加速了大脑老化。 | Jha, P. K. | PDF | N/A | Chronic sleep curtailment expediates brain aging by activating the complement and coagulation cascades in mice | | 转录因子指导植物生殖组织中的DNA甲基化模式 | Xu, G. | PDF | N/A | Transcription factors instruct DNA methylation patterns in plant reproductive tissues | | 拟南芥REM转录因子和GDE1通过招募RNA聚合酶IV转录复合物来塑造DNA甲基化景观。 | Wu, Z. | PDF | N/A | Arabidopsis REM transcription factors and GDE1 shape the DNA methylation landscape through the recruitment of RNA Polymerase IV transcription complexes. | | Nlrp5基因的缺失突变会导致卵母细胞中的从头甲基化减弱，同时伴随着DNMT3L的显著减少。 | Nic Aodha, L. | PDF | N/A | An Nlrp5-null mutation leads to attenuated de novo methylation in oocytes, accompanied by a significant reduction in DNMT3L | | 亚洲栽培稻的全基因组目录 | Contreras-Moreira, B. | PDF | N/A | A pan-gene catalogue of Asian cultivated rice | | 替代氧化酶重新配置了果蝇幼虫的线粒体电子传递系统，以加速其生长和发育。 | Garcia, G. S. | PDF | N/A | The alternative oxidase reconfigures the larval mitochondrial electron transport system to accelerate growth and development in Drosophila melanogaster | | 以下是这段英文的中文翻译：
利用XFELs和同步辐射对耐甲氧西林金黄色葡萄球菌青霉素结合蛋白2a的环境温度结构研究
翻译说明： - Ambient temperature：环境温度 - structural studies：结构研究 - Penicillin-binding Protein 2a：青霉素结合蛋白2a - Methicillin-Resistant Staphylococcus aureus：耐甲氧西林金黄色葡萄球菌（MRSA） - XFELs：X射线自由电子激光器 - synchrotrons：同步辐射光源
希望这个翻译对你有帮助！ | Grieco, A. | PDF | N/A | Ambient temperature structural studies of Penicillin-binding Protein 2a of Methicillin-Resistant Staphylococcus aureus with XFELs and synchrotrons | | 耐甲氧西林金黄色葡萄球菌青霉素结合蛋白2a的环境温度结构研究：利用X射线自由电子激光器和同步辐射光源 | Grieco, A. | PDF | N/A | Ambient temperature structural studies of Penicillin-binding Protein 2a of Methicillin-Resistant Staphylococcus aureus with XFELs and synchrotrons | | 追踪视觉运动配对联合刺激期间皮质脊髓兴奋性的变化，以预测运动共振重写 | Guidali, G. | PDF | N/A | Tracking changes in corticospinal excitability during visuomotor paired associative stimulation to predict motor resonance rewriting | | 成纤维细胞生长因子受体1的激活在阿尔茨海默病小鼠模型中提供了治疗益处 | Hung, W.-C. | PDF | N/A | The activation of fibroblast growth factor receptor 1 provides therapeutic benefit in a mouse model of Alzheimer's disease | | 通过质谱分析鉴定的阿尔茨海默病患者视网膜中tau蛋白磷酸化的变化 | Santiago, J. | PDF | N/A | Alterations in retinal tau phosphorylation in Alzheimer's disease patients identified by mass spectrometry | | 体外重建最小人类中心体 | Rios, M. U. | PDF | N/A | In vitro reconstitution of minimal human centrosomes | | 物候变化的影响取决于每个季节的世代数量。 | Zou, H.-X. | PDF | N/A | Consequences of phenological shifts are determined by the number of generations per season | | Tanimoto 是一种度量标准吗？ | Surendran, A. | PDF | N/A | Is Tanimoto a metric? | | ScatTR：基于短读长测序数据估算长串联重复扩展的长度 | Al-Abri, R. | PDF | N/A | ScatTR: Estimating the Size of Long Tandem Repeat Expansions from Short-Reads | | NO敏感性鸟苷酸环化酶的药物激活改善肥胖引起的动脉硬化 | Seta, F. | PDF | N/A | Pharmacological Activation of NO-Sensitive Guanylyl Cyclase Ameliorates Obesity-Induced Arterial Stiffness | | 三唑187是一种偏向性KOR激动剂，它能在不引起镇静的情况下抑制瘙痒，并在小鼠中诱导类似抗焦虑的行为。 | Volf, A. | PDF | N/A | Triazole 187 is a biased KOR agonist that suppresses itch without sedation and induces anxiolytic-like behaviors in mice. | | 单细胞蛋白质组学揭示马凡小鼠动脉瘤中的新型细胞表型 | Parker, S. J. | PDF | N/A | Single Cell Proteomics Reveals Novel Cell Phenotypes in Marfan Mouse Aneurysm | | 早期类风湿性关节炎-心血管疾病多病共存的蛋白质组学特征研究。 | Shukla, R. | PDF | N/A | Proteomic characterisation of the early rheumatoid arthritis-cardiovascular disease multimorbid axis. | | 在肘屈肌持续收缩过程中，皮质脊髓束、网状脊髓束和运动神经元对疲劳性的贡献 | Hayman, O. | PDF | N/A | Corticospinal, reticulospinal, and motoneuronal contributions to fatigability during a sustained contraction of the elbow flexors | | 前额叶痴呆患者血浆中六糖基神经酰胺水平的降低是白质完整性的生物标志物。 | Marian, O. C. | PDF | N/A | Reduced plasma hexosylceramides in frontotemporal dementia are a biomarker of white matter integrity | | N153连接的糖基化位点位于包膜蛋白上，保护正黄病毒免受抗体介导的清除。 | Ting, D. H. R. | PDF | N/A | N153-linked glycans on envelope protein protect orthoflaviviruses from antibody-mediated clearance | | 人体结缔组织的分布——重建与分类 | Stark, H. | PDF | N/A | The distribution of connective tissue in humans - Reconstruction and classification | | 通过分子动力学模拟轨迹的Jensen-Shannon散度进行蛋白质-配体亲和力预测 | Igarashi, K. | PDF | N/A | Protein-ligand affinity prediction via Jensen-Shannon divergence of molecular dynamics simulation trajectories | | 大规模基因表达分析揭示了表达多样性对现代小麦改良的贡献 | Zhang, Z. | PDF | N/A | Population-scale gene expression analysis reveals the contribution of expression diversity to the modern wheat improvement | | 使用NeuroMark PET独立成分分析框架构建多变量分子成像脑图谱 | Eierud, C. | PDF | N/A | Building Multivariate Molecular Imaging Brain Atlases Using the NeuroMark PET Independent Component Analysis Framework | | 杂合性Sptlc1外显子2缺失小鼠中未发现运动缺陷和类似ALS的神经病理学改变 | Pant, D. C. | PDF | N/A | Lack of motor defects and ALS-like neuropathology in heterozygous Sptlc1 Exon 2 deletion mice | | 神经-心脏引导的经颅磁刺激（TMS）在心脏-大脑耦合中的目标特异性和可重复性 | Feng, Z. | PDF | N/A | Target-Specificity and Repeatability in Neuro-Cardiac-Guided TMS for Heart-Brain Coupling | | Block-Champagne：一种新颖的贝叶斯框架用于成像E/MEG源 | Feng, Z. | PDF | N/A | Block-Champagne: A novel Bayesian framework for Imaging E/MEG Source | | 基于互补体积电子显微镜的方法揭示了黑腹果蝇生殖细胞间桥的超微结构变化。 | Kolotuev, I. | PDF | N/A | Complementary Volume Electron Microscopy-based approaches reveal ultrastructural changes in germline intercellular bridges of D. melanogaster | | 基于完整线粒体基因组的鹅颈藤壶系统发育研究证实了东太平洋的Pollicipes elegans与东大西洋的P. pollicipes之间的姐妹群关系。 | Alfaro, R. | PDF | N/A | A complete mitochondrial genome-based phylogeny of gooseneck barnacles confirms the sister group relationship between the eastern Pacific Pollicipes elegans and the eastern Atlantic P. pollicipes | | 基于质谱的蛋白质组学检测人类未注释的微蛋白：一项社区评估 | Wacholder, A. | PDF | N/A | Detection of human unannotated microproteins by mass spectrometry-based proteomics: a community assessment | | TISSLET 基于组织的转录组学学习估计 | Miloudi, A. | PDF | N/A | TISSLET Tissues-based Learning Estimation for Transcriptomics | | scWGBS-GPT：一种用于捕捉单细胞全基因组亚硫酸氢盐测序中长程CpG依赖性的基础模型，以增强表观遗传分析 | Liang, C. | PDF | N/A | scWGBS-GPT: A Foundation Model for Capturing Long-Range CpG Dependencies in Single-Cell Whole-Genome Bisulfite Sequencing to Enhance Epigenetic Analysis | | 从文学到生物多样性数据：利用机器学习挖掘节肢动物的生物与生态特征 | Cornelius, J. | PDF | N/A | From literature to biodiversity data: mining arthropod organismal and ecological traits with machine learning | | 基于图的对比学习实现单细胞和空间多组学的统一整合与生态位转移 | Zhou, W. | PDF | N/A | Graph-based Contrastive Learning Enables Unified Integration and Niche Transfer Across Single-Cell and Spatial Multi-Omics | | 增长与多样性：化学空间的时间演化分析 | Lopez Perez, K. | PDF | N/A | Growth vs. Diversity: A Time-Evolution Analysis of the Chemical Space | | 通过相互作用价态和体积，膜几何结构调控突触后密度中的多相分离。 | Yamada, R. | PDF | N/A | Multiphase separation in postsynaptic density regulated by membrane geometry via interaction valency and volume | | 蛋白质二聚化驱动的DNA靶标选择性增强或减弱的机制 | Sang, M. | PDF | N/A | Mechanisms of enhanced or impaired DNA target selectivity driven by protein dimerization | | 肿瘤治疗电场抑制胆道癌细胞增殖并促进免疫原性细胞死亡 | Yue, Y. | PDF | N/A | Tumor Treating Fields inhibit cell proliferation and promote immunogenic cell death in biliary tract cancer cells | | 一种含有烟酰胺核苷、叶酸和钴胺素的B族维生素混合物，在心力衰竭小鼠模型中能够保护心脏功能并维持线粒体的氧化能力。 | Boitard, S. E. | PDF | N/A | A cocktail of B vitamins with nicotinamide riboside, folate and cobalamin preserves cardiac function and mitochondrial oxidative capacities in a mouse model of heart failure. | | 母子自主神经系统互动作为父母压力的指标：24小时交叉递归图分析 | Li, J. | PDF | N/A | Mother-child autonomic nervous system interaction as an indication of parental stress: 24-hour cross recurrence plot analysis | | 肾皮质巨噬细胞通过从尿液中重吸收磷酸盐来防止矿物质结石的形成。 | Wang, Y. | PDF | N/A | Kidney cortex macrophages prevent the formation of mineral stones by reabsorbing phosphate from the urine | | 通过极端表型策略对新疆汉族青年脂质代谢调控的遗传分析 | Yu, J. | PDF | N/A | A Genetic Analysis of Lipid Metabolism Regulation in Han Chinese Youth in Xinjiang via Extreme Phenotypic Strategies | | 夜间人工照明对雄性萤火虫求偶行为的多重影响 | Moubarak, E. M. | PDF | N/A | Multiple Effects of Artificial Lighting at Night on Male Glow-worms' Mate Searching Behaviour | | 来自农业和纸张废料的菌丝体生物复合材料：塑料泡沫二次包装的可持续替代品 | Kundanati, L. | PDF | N/A | Mycelium Biocomposites from Agricultural and Paper waste: Sustainable alternative to plastic foam based secondary packaging | | 在基于折叠的功能预测时代追溯原始蛋白质折叠的功能扩展：β-三叶形折叠 | Srinivasan, S. | PDF | N/A | Tracing the function expansion for a primordial protein fold in the era of fold-based function prediction: beta-trefoil | | 病理分割中的标签噪声问题被忽视，可能导致人工智能模型的高估。 | Harada, K. | PDF | N/A | Label Noise in Pathological Segmentation is Overlooked, Leading to Potential Overestimation of Artificial Intelligence Models | | ESMStabP：一种用于蛋白质热稳定性预测的回归模型 | Ramos, M. A. | PDF | N/A | ESMStabP: A Regression Model for Protein Thermostability Prediction | | BADDADAN：时间序列基因模块表达的机制建模 | Noordijk, B. | PDF | N/A | BADDADAN: Mechanistic Modelling of Time Series Gene Module Expression | | 通过电扩散高斯-能斯特-普朗克方法研究通道修正与神经动力学 | Liu, Z. | PDF | N/A | Investigate Channel Rectifications and Neural Dynamics by An Electrodiffusive Gauss-Nernst-Planck Approach | | 一种基因特征预测侵袭性副神经节瘤对双重PI3K-CDK4/6抑制疗法的敏感性 | Karna, B. | PDF | N/A | A genetic signature predicts aggressive paraganglioma sensitivity to dual PI3K-CDK4/6 inhibition therapy | | BRCA1-A和LIG4复合物介导ecDNA的生物生成和癌症耐药性 | Chung, O. | PDF | N/A | BRCA1-A and LIG4 complexes mediate ecDNA biogenesis and cancer drug resistance | | 利什曼原虫亚马逊亚种感染在C57BL/6小鼠中诱导了依赖于IL1β的痛觉过敏，同时减弱了机械性异常痛觉。 | Guadagnini Perez, G. | PDF | N/A | Leishmania amazonensis infection induces IL1β-dependent hyperalgesia, while dampening mechanical allodynia in C57BL/6 mice | | 制备与表征负载甲氨蝶呤的聚乳酸-羟基乙酸共聚物（PLGA）纳米粒子的透明质酸/桉树水凝胶作为类风湿性关节炎的可注射疗法 | Castilla Bolanos, M. A. | PDF | N/A | Fabrication & characterization of hyaluronic acid/eucalyptus hydrogels loaded with PLGA nanoparticles with methotrexate as an Injectable therapy for rheumatoid arthritis | | 在编码线粒体RNA聚合酶的核基因中进行人工突变，可以恢复细胞质雄性不育番茄的花粉育性。 | Kuwabara, K. | PDF | N/A | Artificial mutations in the nuclear gene encoding mitochondrial RNA polymerase restore pollen fertility in cytoplasmic male sterile tomato | | 以下是这段英文的中文翻译：
褪黑素介导的甲基乙二醛稳态及自噬调控在PEG诱导的干旱胁迫下陆地棉种子萌发中的作用
翻译说明： - Melatonin-mediated：褪黑素介导的 - methylglyoxal homeostasis：甲基乙二醛稳态 - regulation of autophagy：自噬调控 - seed germination：种子萌发 - PEG-induced drought stress：PEG诱导的干旱胁迫 - upland cotton：陆地棉
希望这对你有帮助！ | Dake, D. | PDF | N/A | Melatonin-mediated methylglyoxal homeostasis and regulation of autophagy during seed germination under PEG-induced drought stress in upland cotton | | ProteoAutoNet：利用机器人技术和多数据库搜索策略进行高通量共洗脱蛋白质分析 | Lyu, M. | PDF | N/A | ProteoAutoNet: high-throughput co-eluted protein analysis with robotics and a multi-database search strategy | | 控制突触中多重凝聚物的形成 | Safari, N. | PDF | N/A | Controlling the Formation of Multiple Condensates in the Synapse | | 后生动物RNase MRP的组成及RNA结合特异性 | Liu, Y. | PDF | N/A | Composition and RNA binding specificity of metazoan RNase MRP | | Cdk1和PP2A构成了一个分子开关，控制非典型E2Fs的有序降解。 | Nachum-Raines, S. | PDF | N/A | Cdk1 and PP2A constitute a molecular switch controlling orderly degradation of atypical E2Fs | | 中脑核素-蛋白酶体途径的结构基础及其在抑制多发性骨髓瘤中的作用 | Nardone, C. | PDF | N/A | Structural basis for the midnolin-proteasome pathway and its role in suppressing myeloma | | 长读RNA测序技术鉴定出一种新型长链非编码RNA的异构体转换，该转换促进体细胞重编程。 | Fort, V. | PDF | N/A | Long-read RNA sequencing identifies isoform switching of a novel long non-coding RNA that promotes somatic cell reprogramming | | 造血干细胞在体内经历双向命运转变。 | Fukushima, T. | PDF | N/A | Hematopoietic stem cells undergo bidirectional fate transitions in vivo. | | 环状RNA Circ-Cdr1as通过Circ-Cdr1as-miR-7-Klf4通路调控巨噬细胞表型及心脏修复功能
这段文字描述了一个生物学机制，其中环状RNA（Circ-Cdr1as）通过特定的分子通路（Circ-Cdr1as-miR-7-Klf4）来影响巨噬细胞的表型（即巨噬细胞的功能状态和特性）以及心脏的修复功能。具体来说，Circ-Cdr1as通过调控miR-7和Klf4的表达，进而影响巨噬细胞的行为和心脏组织的修复过程。 | Kishore, R. | PDF | N/A | Circular RNA Circ-Cdr1as modulates Macrophage phenotype and Cardiac Reparative Function by Circ-Cdr1as-miR-7-Klf4 pathway | | 在适配蛋白复合物4缺陷的神经元模型中进行的CRISPR/Cas9功能缺失筛选阵列，识别了ATG9A运输的调节因子 | Ziegler, M. | PDF | N/A | Arrayed CRISPR/Cas9 Loss-Of-Function Screen in a Neuronal Model of Adaptor Protein Complex 4 Deficiency Identifies Modulators of ATG9A Trafficking | | DNA合成的空间映射揭示了人类复制纳米结构的动态和几何特征 | Hawgood, M. | PDF | N/A | Spatial mapping of DNA synthesis reveals dynamics and geometry of human replication nanostructures | | 患者来源的类器官用于研究胃病期间的糖基化动态 | Santos-Ferreira, L. | PDF | N/A | Patient-derived organoids to study glycosylation dynamics during gastric disease | | 胰腺中的IMPDH细胞质体：形态动力学与代谢意义
这段翻译将原文中的“IMPDH Cytoophidia”翻译为“IMPDH细胞质体”，其中“Cytoophidia”是一个专业术语，通常指细胞内的某种结构或形态。根据上下文，这里可能指的是与IMPDH（肌苷单磷酸脱氢酶）相关的细胞内结构。接下来的“Morphological Dynamics”翻译为“形态动力学”，指的是这些结构在形态上的变化和动态过程。“Metabolic Implications”则翻译为“代谢意义”，指的是这些结构在细胞代谢中的作用和影响。整个翻译力求准确传达原文的专业性和科学含义。 | Huang, Y. | PDF | N/A | IMPDH Cytoophidia in the Pancreas: Morphological Dynamics and Metabolic Implications | | 一份关于活体捐赠者的空间转录组学图谱揭示了健康人类肝脏中独特的区域化模式。 | Yakubovsky, O. | PDF | N/A | A spatial transcriptomics atlas of live donors reveals unique zonation patterns in the healthy human liver | | 细胞运动性影响单细胞RNA测序中的微流控捕获 | Lopez-Escobar, L. | PDF | N/A | Cell motility influences microfluidics capturing in scRNA-seq | | 受体酪氨酸激酶AXL通过粘附-Arf1信号轴调节乳腺癌和肺癌中的高尔基体组织和功能 | Joshi, P. | PDF | N/A | Receptor tyrosine kinase AXL regulates Golgi organization and function through an adhesion-Arf1 signaling axis in breast and lung cancers | | 在酵母中进行动态细胞器定位研究揭示了内质网应激期间蛋白质定位的广泛变化。 | Platzek, A. | PDF | N/A | Dynamic Organellar Mapping in yeast reveals extensive protein localization changes during ER stress | | MLL2在控制多能细胞分化启动过程中的染色质组织和流动性中的非催化作用 | Steindel, M. | PDF | N/A | A non-catalytic role for MLL2 in controlling chromatin organisation and mobility during the priming of pluripotent cells for differentiation | | 深度学习预测视网膜类器官中的组织结果 | Afting, C. | PDF | N/A | Deep learning predicts tissue outcomes in retinal organoids | | NEDD4在小鼠睾丸中促进支持细胞增殖和成年间质细胞分化。 | Windley, S. P. | PDF | N/A | NEDD4 promotes Sertoli cell proliferation and adult Leydig cell differentiation in the murine testis | | Myo2适配器Ldm1及其受体Ldo16介导依赖于肌动蛋白的脂滴运动 | Zhao, X.-T. | PDF | N/A | The Myo2 adaptor Ldm1 and its receptor Ldo16 mediate actin-dependent lipid droplet motility | | ERM蛋白支持核周肌动蛋白边缘的形成 | Fracchia, A. | PDF | N/A | ERM proteins support perinuclear actin rim formation | | 高通量微电子衍射技术用于探测离子通道动力学 | Gallenito, M. J. | PDF | N/A | High-throughput MicroED for probing ion channel dynamics | | 复杂轨迹：运用复杂适应系统方法研究19世纪南澳大利亚移民的发病率和死亡率 | Gurr, A. | PDF | N/A | Complex Traces: Using a Complex Adaptive Systems approach to examine morbidity and mortality among 19th Century migrants to South Australia | | 细菌中的细胞大小调控：一个关于古老调控因子与新机制的故事 | Khan, E. | PDF | N/A | Cell size regulation in bacteria: a tale of old regulators with new mechanisms | | 新型Goniomonad属Ebisugoniomonas及两种新型Poseidogoniomonas物种的形态学和小亚基rDNA基因系统发育研究 | Zavadska, D. | PDF | N/A | The morphology and small subunit rDNA gene phylogeny of the novel goniomonad genus Ebisugoniomonas and two novel Poseidogoniomonas species | | 在现代微生物岩礁中，模拟早期地球环境下的季节性生物地球化学变化 | Vignale, F. | PDF | N/A | Seasonal biogeochemical variations in a modern microbialite reef under early Earth-like conditions | | 用于治疗非洲锥虫病的硫属元素衍生物：硫代和硒代半碳酰腙及其氮唑衍生物的生物评价 | Rubio-Hernandez, M. | PDF | N/A | Chalcogen derivatives for the treatment of African trypanosomiasis: biological evaluation of thio and seleno- semicarbazones and their azole derivatives | | 在甲烷富集培养中，脱卤杆菌（Dehalobacter）通过2-氯苯胺将2,3-二氯苯胺转化为苯胺。 | Wang, S. | PDF | N/A | Dehalobacter converts 2,3-dichloroaniline to aniline via 2-chloroaniline in a methanogenic enrichment culture | | 随机组装与代谢网络重组驱动干旱土壤中微生物的恢复力 | Ayala-Ortiz, C. O. | PDF | N/A | Stochastic Assembly and Metabolic Network Reorganization Drive Microbial Resilience in Arid Soils | | 采用整合的元组学方法识别复杂微生物群落中有机微污染物降解的候选菌种 | Elad, T. | PDF | N/A | An integrated meta-omics approach for identifying candidate organic micropollutant degraders in complex microbial communities | | 填补抗体反应与动物福利之间的鸿沟：评估鼻内淋球菌疫苗接种小鼠的血液采集方法与阴道免疫反应
在这项研究中，我们旨在评估不同血液采集方法对小鼠抗体反应的影响，并探讨鼻内淋球菌疫苗接种后小鼠阴道免疫反应的变化。通过对比不同采血技术，我们不仅能够更准确地监测免疫反应，还能优化实验流程，从而在科学研究中更好地平衡实验需求与动物福利。这一研究不仅为疫苗开发提供了重要数据，也为改进实验动物管理策略提供了科学依据。 | Chanda, A. | PDF | N/A | Bridging Gaps in Antibody Responses and Animal Welfare: Assessing Blood Collection Methods and Vaginal Immunity in Mice Immunized with Intranasal Gonococcal Vaccines | | AMPK介导电针在脑缺血再灌注大鼠中的抗铁死亡作用 | Wang, R. | PDF | N/A | AMPK mediates the anti-ferroptosis effect of acupuncture in cerebral ischemia-reperfusion rats | | 复制体在体内限制SMC介导的DNA环挤压 | Liao, Q. | PDF | N/A | Replisomes restrict SMC-mediated DNA-loop extrusion in vivo | | 端粒酶修饰RNA（Telomerase modRNA）提供了一种基于RNA的新方法，用于治疗人类肺纤维化。 | Ye, J. L. | PDF | N/A | Telomerase modRNA offers a novel RNA-based approach to treat human pulmonary fibrosis | | D4Z4的一个离散区域足以启动表观遗传沉默。 | Paatela, E. M. | PDF | N/A | A discrete region of the D4Z4 is sufficient to initiate epigenetic silencing | | PRDM16在动脉粥样硬化中控制平滑肌细胞的命运 | Tan, J. | PDF | N/A | PRDM16 controls smooth muscle cell fate in atherosclerosis | | 染色质保留的MUSHER长链非编码RNA整合了ABA和DOG1信号通路，以增强拟南芥种子的休眠。 | Sacharowski, S. | PDF | N/A | Chromatin retained MUSHER lncRNA integrates ABA and DOG1 signalling pathways to enhance Arabidopsis seeds dormancy. | | 通过对福尔马林固定石蜡包埋组织进行空间总RNA测序——spRandom-seq方法 | Liao, Y. | PDF | N/A | Spatial Total RNA Sequencing of Formalin-Fixed Paraffin Embedded Tissues by spRandom-seq | | EvANI基准测试工作流程用于进化距离估计 | Majidian, S. | PDF | N/A | EvANI benchmarking workflow for evolutionary distance estimation | | 多模态空间转录组学与组织病理学成像的解耦 | Maan, H. | PDF | N/A | Multi-modal Disentanglement of Spatial Transcriptomics and Histopathology Imaging | | 生物信息学分析确定了与PHARC相关的脂肪酶ABHD12酶活性的序列决定因素。 | Chakraborty, A. | PDF | N/A | Bioinformatics analysis identifies sequence determinants of enzymatic activity for the PHARC associated lipase ABHD12 | | 抑制甲基硫腺苷磷酸化酶可保护实验性急性肾损伤 | Saliba, A. | PDF | N/A | Inhibition of methylthioadenosine phosphorylase provides protection from experimental acute kidney injury | | 在自然感染的牛中，牛白血病病毒和牛泡沫病毒来源的miRNAs的共表达 | Petersen, M. I. | PDF | N/A | Co-expression of Bovine leukemia virus and Bovine foamy virus-derived miRNAs in naturally infected cattle | | 2025年印度家猫感染高致病性禽流感A（H5N1）分支2.3.2.1a病毒 | Raut, A. A. | PDF | N/A | Highly Pathogenic Avian Influenza A (H5N1) Clade 2.3.2.1a virus infection in domestic cats, India, 2025 | | 泥土地面和家畜与孟加拉国农村家庭中土壤传播的耐抗生素大肠杆菌暴露有关。 | Ercumen, A. | PDF | N/A | Dirt floors and domestic animals are associated with soilborne exposure to antimicrobial resistant E. coli in rural Bangladeshi households | | 配体诱导的Apelin受体激活中的动态单体-二聚体转换 | Ji, S. | PDF | N/A | Dynamic Monomer-Dimer Transition in Ligand-induced Apelin Receptor Activation | | 小鼠Stat5b的Y665F变体通过肾脏基因表达的转录组变化来防止急性肾损伤 | Jankowski, J. | PDF | N/A | Y665F variant of mouse Stat5b protects against acute kidney injury through transcriptomic shifts in renal gene expression | | 体细胞重复元件插入定义了泛癌基因组中的新生物标志物 | Xia, L. | PDF | N/A | Somatic repetitive element insertions Define New Biomarkers in Pan-cancer genome | | 绘制猪基因组中等位基因特异性表达图谱 | Yao, W.-y. | PDF | N/A | Mapping the Landscape of Allele-Specific Expression In Porcine Genomes |