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Onlinemeta:基于Shiny框架的元分析网络服务器 Dai, W. PDF N/A Onlinemeta: A Web Server for Meta-Analysis Based on Shiny Framework
捕捉LIS1型无脑回畸形类器官模型中疾病严重程度的生物学特征 Zillich, L. PDF N/A Capturing the biology of disease severity in an organoid model of LIS1-lissencephaly
评估环境DNA(eDNA)分析在海洋环境产卵调查中的潜力:以日本竹荚鱼为例的研究 Tsuji, S. PDF N/A Assessing the potential of eDNA analysis for spawning surveys in marine environments: A case study on Japanese jack mackerel
一种促凋亡脂质对线粒体蛋白质导入和蛋白质稳态的抑制作用 Fita-Torro, J. PDF N/A Inhibition of mitochondrial protein import and proteostasis by a pro-apoptotic lipid
PIM激酶对CD8 T细胞蛋白质合成和细胞运输的调控 Marchingo, J. M. PDF N/A PIM kinase control of CD8 T cell protein synthesis and cell trafficking
从空间快照看时间组织动态 Somer, J. PDF N/A Temporal tissue dynamics from a spatial snapshot
Locityper:复杂多态性基因的定向基因分型 Prodanov, T. PDF N/A Locityper: targeted genotyping of complex polymorphic genes
Locityper:复杂多态性基因的定向基因分型 Prodanov, T. PDF N/A Locityper: targeted genotyping of complex polymorphic genes
STEMorph:一组从愤怒到快乐的情绪面部刺激,源自NimStim Katebi, M. E. PDF N/A STEMorph: A Set of Morphed Emotional Face Stimuli from Angry to Happy Derived from NimStim
使用铁氧体微粒(ferumoxytol)加权层析MRI技术绘制灵长类大脑血管网络结构 Autio, J. A. PDF N/A Mapping vascular network architecture in primate brain using ferumoxytol-weighted laminar MRI
小脑浦肯野细胞对舌头运动的控制 Hage, P. PDF N/A Control of tongue movements by the Purkinje cells of the cerebellum
分层截断精确检验的伽马近似法(GASTE检验)及应用 Wendling, A. PDF N/A Gamma Approximation of Stratified Truncated Exact test (GASTE-test) & Application
通过调节GSK3活性重新编程依赖GM-CSF的肺泡巨噬细胞 Rios, I. PDF N/A Re-programming of GM-CSF-dependent alveolar macrophages through GSK3 activity modulation
病毒介导的Oct4过表达和Notch信号抑制协同诱导哺乳动物Muller胶质细胞的神经源性能力。 Le, N. PDF N/A Viral-mediated Oct4 overexpression and inhibition of Notch signaling synergistically induce neurogenic competence in mammalian Muller glia.
GeneCover:一种用于无标记基因选择的组合方法 Wang, A. PDF N/A GeneCover: A Combinatorial Approach for Label-free Marker Gene Selection
Nano3P-seq:以单分子分辨率绘制编码和非编码转录组图谱 Begik, O. PDF N/A Nano3P-seq: charting the coding and non-coding transcriptome at single molecule resolution
通过DNA语言模型解读宏基因组读段中的酶潜力 R, P. PDF N/A Deciphering enzymatic potential in metagenomic reads through DNA language model
非稀释结合与表面相分离理论在膜结合蛋白中的应用 Zhao, X. PDF N/A Theory of non-dilute binding and surface phase separation applied to membrane-binding proteins
表皮细胞动力学通过调控OsZHD1和OsZHD2来调节水稻叶枕关节形态发生和叶片角度形成。 Xu, Y. PDF N/A Epidermal Cell Dynamics Regulates Rice Lamina Joint Morphogenesis and Leaf Angle Formation through OsZHD1 and OsZHD2 Regulation
通过脑电图和模型指导的功能性磁共振成像揭示人类顶内沟在证据累积中的作用 Wongtrakun, J. PDF N/A The role of human intraparietal sulcus in evidence accumulation revealed by EEG and model-informed fMRI
互联网上的图片揭示了一种模仿大黄蜂的食蚜蝇,它们已经进化到能够追随其模仿对象——大黄蜂对花朵颜色的偏好。 Gilbert, J. D. PDF N/A Internet images reveal bumblebee-mimicking hoverflies have evolved to follow flower colour preferences of their models
胆固醇介导的APOE4星形胶质细胞溶酶体功能障碍促进人脑组织中α-突触核蛋白病理 Mesentier-Louro, L. A. PDF N/A Cholesterol-mediated Lysosomal Dysfunction in APOE4 Astrocytes Promotes α-Synuclein Pathology in Human Brain Tissue
后生动物幼虫纤毛带中同步波的动态与涌现 Poon, R. N. PDF N/A Dynamics and emergence of metachronal waves in the ciliary band of a metazoan larva
突触的纳米级组织结构决定了皮质神经元树突棘的突触释放特性。 Jafri, H. PDF N/A Nano-organization of synapses defines synaptic release properties at cortical neuron dendritic spines
信息复杂性作为认知储备的神经标记 Stolp, L. PDF N/A Informational Complexity as a Neural Marker of Cognitive Reserve
感知加速过程中的变量处理变化:来自时间整合的证据 Wolff, M. J. PDF N/A Variable processing shifts during perceptual acceleration: Evidence from temporal integration
在细胞周期进程中,Sec24C通过磷酸化和O-GlcNAc糖基化进行动态调控 Georgiou, G. R. PDF N/A Dynamic regulation of Sec24C by phosphorylation and O-GlcNAcylation during cell cycle progression
糖皮质激素在小鼠皮层神经元发育过程中调节神经元周围网络组分基因和小白蛋白的表达。 Morris, B. PDF N/A Glucocorticoids modulate expression of perineuronal net component genes and parvalbumin during development of mouse cortical neurons
研究自然行为之外肌肉活动模式学习的一种范式 Ghavampour, A. PDF N/A A paradigm to study the learning of muscle activity patterns outside of the natural repertoire
整合的人类和小鼠星形胶质细胞跨疾病图谱揭示了神经退行性疾病中星形胶质细胞亚型的异质性和保守性 Lucas, T. A. PDF N/A Integrated Cross-Disease Atlas of Human And Mouse Astrocytes Reveals Heterogeneity and Conservation of Astrocyte Subtypes in Neurodegeneration
婴儿从出生到6个月期间白质成熟的动态变化 Risk, B. PDF N/A Dynamics of infant white matter maturation from birth to 6 months
在群体基因组数据中识别单一来源的稀有变异 Reynolds, J. J. PDF N/A Identifying single origin rare variants in population genomic data
StackGlyEmbed:使用蛋白质语言模型预测N-连接糖基化位点 Nafi, M. M. I. PDF N/A StackGlyEmbed: Prediction of N-linked Glycosylation sites using protein language models
钙离子诱导的N端门控和孔道塌陷在连接蛋白46/50间隙连接中的作用 Flores, J. A. PDF N/A Calcium induced N-terminal gating and pore collapse in connexin-46/50 gap junctions
TinA 使驱动蛋白-14/KlpA 能够表现出持续的向负端运动的特性。 Visootsat, A. PDF N/A TinA enables kinesin-14/KlpA to exhibit processive minus-end-directed motility
使用全原子模拟和人工智能发现新的类淀粉样肽。 Kuang, X. PDF N/A Discovering new amyloid-like peptides using all-atom simulations and artificial intelligence.
微管细胞骨架对β细胞中胰岛素运输的影响:一项三维计算研究 Thieu, T. PDF N/A Impact of the Microtubule Cytoskeleton on Insulin Transport in Beta Cells: A 3D Computational Study
通过分子模拟揭示H2A和H2B泛素化在核小体动力学中的相反作用 Baweja, L. PDF N/A The Opposing Roles of H2A and H2B Ubiquitination on Nucleosome Dynamics Revealed by Molecular Simulations
通过冷冻电镜技术揭示连接蛋白-46/50的pH门控机制及其可逆性脂质调控 Jarodsky, J. M. PDF N/A Reversible lipid mediated pH-gating of connexin-46/50 by cryo-EM
分子动力学模拟揭示了M. smegmatis拓扑异构酶1A的DNA门开启机制 Sigdel, D. PDF N/A Molecular dynamics simulations reveal DNA gate opening mechanisms for M. smegmatis topoisomerase 1A
使用能量函数对多室植物细胞中的离子稳态进行多物理场建模 Mestdagh, G. PDF N/A Multi-physics modeling for ion homeostasis in multi-compartment plant cells using an energy function
使用AlphaFold2预测折叠蛋白质中侧链的构象 Maisuradze, G. PDF N/A Using AlphaFold2 to Predict the Conformations of Side Chains in Folded Proteins
探究膜在抗流感病毒抗体中和活性中的作用 Ozgulbas, D. G. PDF N/A Probing the Role of Membrane in Neutralizing Activity of Antibodies Against Influenza Virus
通过茎/连接区域控制微管相关蛋白的受力特性:来自NDC80复合物的见解 Kovalenko, I. B. PDF N/A Control of the force-bearing properties of microtubule-associated proteins via stalk/linker regions: insights from the NDC80 complex
两步发条机制在PIEZO2通道中打开一个蛋白质-脂质孔 Li, S. PDF N/A A two-step clockwork mechanism opens a proteo-lipidic pore in PIEZO2 channels
长程静电力决定了蛋白质在核糖体上的折叠方式。 Streit, J. PDF N/A Long-range electrostatic forces govern how proteins fold on the ribosome
细菌病原体利用亚氨基糖半乳糖苷来操纵植物糖生物学 Sanguankiattichai, N. PDF N/A Bacterial pathogen deploys iminosugar galactosyrin to manipulate plant glycobiology
烟雾暴露会引发快速的转录变化,并揭示出与成熟葡萄浆果中烟雾污染相关的糖基转移酶。 Paineau, M. PDF N/A Smoke exposure triggers rapid transcriptional changes and reveals glycosyltransferases linked to smoke taint in ripening grape berries
一个世纪的平衡选择理论 Ruzicka, F. PDF N/A A century of theories of balancing selection
TF2TG:一个挖掘果蝇转录因子潜在基因靶标的在线资源 Hu, Y. PDF N/A TF2TG: an online resource mining the potential gene targets of transcription factors in Drosophila
基于现场可编程门阵列的超低功耗离散傅里叶变换用于闭环神经传感 Yang, R. PDF N/A Field-Programmable Gate Array Based Ultra-Low Power Discrete Fourier Transforms for Closed-Loop Neural Sensing
来自经验和观察的证据在扣带皮层中的积累 Chen, R. PDF N/A Evidence accumulation from experience and observation in the cingulate cortex
阶段性疼痛和持续性疼痛在适应行为中发挥不同的功能。 Tong, S. PDF N/A Phasic and tonic pain serve distinct functions during adaptive behaviour
《在清醒的极限中游走:探索梦境中运动实践的认知限制》 Peters, E. PDF N/A Juggling the Limits of Lucidity: Searching for Cognitive Constraints in Dream Motor Practice
长期评估支配地位、围兜尺寸、性别和年龄之间的关联 Silva, N. J. PDF N/A Long-term evaluation of the association between dominance, bib size, sex and age
比较计算对接分析:MPP+和多巴胺与人类和斑马鱼多巴胺转运体的结合——MPTP神经毒性的机制研究

这段翻译将英文标题转换为中文,同时保持了原文的专业性和准确性。标题中的“Comparative Computational Docking Analysis”翻译为“比较计算对接分析”,“MPP+ and Dopamine Binding to Dopamine Transporter”翻译为“MPP+和多巴胺与多巴胺转运体的结合”,“in Human and Zebrafish”翻译为“在人类和斑马鱼中”,“Mechanistic Insights into MPTP Neurotoxicity”翻译为“MPTP神经毒性的机制研究”。整体翻译流畅,符合中文表达习惯。 | Razali, K. | PDF | N/A | Comparative Computational Docking Analysis of MPP+ and Dopamine Binding to Dopamine Transporter in Human and Zebrafish: Mechanistic Insights into MPTP Neurotoxicity | | 对C9orf72突变诱导多能干细胞(iPSC)衍生的微胶质细胞进行转录组分析表明,在运动神经元退化过程中,特定的NLRP3炎症小体基因在细胞自主性上上调。 | Pulimood, N. S. | PDF | N/A | Transcriptomic analysis of C9orf72-mutated iPSC-derived microglia implicates cell-autonomous upregulation of selected NLRP3 inflammasome genes in motor neuron degeneration | | 斑马鱼行为信用分配的神经回路 | Paoli, E. | PDF | N/A | A zebrafish circuit for behavioral credit assignment | | SpaceBar 能够在空间转录组数据中实现克隆追踪。 | Kinsler, G. | PDF | N/A | SpaceBar enables clone tracing in spatial transcriptomic data | | 珊瑚毒液和毒素作为对抗棘冠海星攻击的防护手段 | Gorman, L. M. | PDF | N/A | Coral venom and toxins as protection against crown-of-thorns sea star attack | | 土地利用历史导致公园夜间降温能力和森林结构存在差异 | Richmond, I. C. | PDF | N/A | Land-use history causes differences in park nighttime cooling capacity and forest structure | | 酵母中金属交叉耐受性的进化 | Bazzicalupo, A. | PDF | N/A | Evolution of cross-tolerance to metals in yeast | | Res ipSAE loquunt: AlphaFold的ipTM评分出了什么问题以及如何修复 | Dunbrack, R. | PDF | N/A | Res ipSAE loquunt: What's wrong with AlphaFold's ipTM score and how to fix it | | 在IMPACC研究中,识别出一种多组学因子可预测长期COVID(长新冠)。 | Gabernet, G. | PDF | N/A | Identification of a multi-omics factor predictive of long COVID in the IMPACC study | | 误导性的监测:更多的幼龟孵化并不代表海龟种群的恢复 | Norris, D. | PDF | N/A | Misleading monitoring: more hatchlings do not represent turtle population recovery | | 一款多功能微型双光子显微镜,可实现多色深脑成像 | Wu, R. | PDF | N/A | A versatile miniature two-photon microscope enabling multicolor deep-brain imaging | | 基于个体特征的个性化连接组深度生成 | Liu, Y. | PDF | N/A | Deep generation of personalized connectomes based on individual attributes | | 在生理性焦虑中,强化学习和工作记忆系统的双重过程损伤是学习缺陷的基础。 | Senta, J. | PDF | N/A | Dual process impairments in reinforcement learning and working memory systems underlie learning deficits in physiological anxiety | | 神经科学的发展演变 | Senden, M. | PDF | N/A | The Evolving Landscape of Neuroscience | | 单细胞RNA测序揭示感染十足目虹彩病毒1的罗氏沼虾(Macrobrachium rosenbergii)中血细胞异质性、分化轨迹及病毒趋向性

这段翻译将英文标题转换为中文,同时保持了科学术语的准确性和专业性。标题中提到的“Single-Cell RNA Sequencing”翻译为“单细胞RNA测序”,“Hemocyte Heterogeneity”翻译为“血细胞异质性”,“Differentiation Trajectories”翻译为“分化轨迹”,“Viral Tropism”翻译为“病毒趋向性”,而“Decapod Iridescent Virus 1”则翻译为“十足目虹彩病毒1”。整个标题清晰地传达了研究的核心内容和研究对象。 | Xiao, B. | PDF | N/A | Single-Cell RNA Sequencing Reveals Hemocyte Heterogeneity, Differentiation Trajectories, and Viral Tropism in Shrimp (Macrobrachium rosenbergii) Infected with Decapod Iridescent Virus 1 | | 探讨后疫情时代可持续洗手行为背景下日常卫生清洁产品的有效性 | Mukherjee, S. | PDF | N/A | Addressing efficacy of everyday hygiene cleansing products in context of sustainable handwashing behavior in the post-pandemic era | | 利用attP着陆位点和gypsy逆转录病毒绝缘子来识别和研究RNA沉默的病毒抑制因子 | Gupta, A. K. | PDF | N/A | Exploiting attP landing sites and gypsy retrovirus insulators to identify and study viral suppressors of RNA silencing | | 利用RiboMarker(R)增强的RNA测序技术对球孢子菌不同形态的转录组变化进行表征 | Howard, J. M. | PDF | N/A | Characterization of transcriptomic changes across Coccidioides morphologies using RiboMarker(R)-enhanced RNA sequencing | | 线粒体呼吸的改变与寄生性列当科植物中核编码的氧化磷酸化(OXPHOS)基因的丢失有关。 | Cai, L. | PDF | N/A | Altered mitochondrial respiration is associated with loss of nuclear-encoded OXPHOS genes in parasitic broomrapes | | 以下是将这段英文翻译成中文的结果:

一种用于英国兽医中心抗菌素耐药性一体化健康监测的宏基因组学方法

解释: - metagenomic approach:宏基因组学方法 - One Health surveillance:一体化健康监测(One Health 是一种跨学科合作的方法,旨在实现人类、动物和环境的最佳健康) - antimicrobial resistance:抗菌素耐药性 - UK veterinary centre:英国兽医中心

整体翻译为:一种用于英国兽医中心抗菌素耐药性一体化健康监测的宏基因组学方法。 | Elton, L. | PDF | N/A | A metagenomic approach to One Health surveillance of antimicrobial resistance in a UK veterinary centre | | 使用通勤时间矩阵进行单细胞轨迹推断的替代方法 | Houston, D. W. | PDF | N/A | Alternative approaches to single-cell trajectory inference using a commute time matrix | | 开发基础模型用于智能监测中预测病毒动物宿主范围 | Guo, J. | PDF | N/A | Developing Foundation Models for Predicting Viral Animal Host Range in Intelligent Surveillance | | 设计具有精确调控动力学特性的蛋白质序列 | Brotzakis, Z. F. | PDF | N/A | Design of Protein Sequences with Precisely Tuned Kinetic Properties | | LCLNCRdb:一个用于研究肺癌中长链非编码RNA的综合资源 | Dwivedi, A. | PDF | N/A | LCLNCRdb: A Comprehensive Resource for Investigating long non-coding RNAs in Lung Cancer | | SEEDS:模拟DNA存储中错误的出现 | Naznin, M. F. S. | PDF | N/A | SEEDS: Simulating Emergence of Errors in DNA Storage | | 淀粉样前体蛋白通过建立免疫排斥的肿瘤微环境促进肿瘤生长 | Yin, T. | PDF | N/A | Amyloid-β precursor protein promotes tumor growth by establishing an immune-exclusive tumor microenvironment | | 对热带大型钝眼蜱(Amblyomma variegatum)进行解剖和内部观察 | Pature, N. | PDF | N/A | Dissection and internal observation of the giant tropical bont tick Amblyomma variegatum | | 经颅磁刺激减少了感知决策中的非决策时间 | Gordleeva, S. | PDF | N/A | Transcranial Magnetic Stimulation Reduces Non-Decision Time in Perceptual Decisions | | TGIF2是神经干细胞命运和神经源性启动的主要调节因子。 | Li, Y. | PDF | N/A | TGIF2 is a major regulator of neural stem cell fate and neurogenic priming | | 脑磁图揭示COVID-19疫苗在非人类灵长类动物中的神经保护作用 | Stapleton-Kotloski, J. | PDF | N/A | Magnetoencephalography Reveals Neuroprotective Effects of COVID-19 Vaccination in Non-Human Primates | | 针对乙型肝炎病毒的mRNA-LNP疫苗在预防性和慢性小鼠挑战模型中诱导出保护性免疫反应。 | Limeres, M. J. | PDF | N/A | mRNA-LNP vaccines against Hepatitis B virus induce protective immune responses in preventive and chronic mouse challenge models | | 人类I型干扰素ω具有强效的抗病毒特性,并能促进细胞毒性CD8+ T细胞反应。 | Nguyen, H. O. | PDF | N/A | Human type-I interferon omega holds potent antiviral properties and promotes cytolytic CD8+ T cell responses | | SA55广泛中和SARS-CoV-2,并有效防止JN.1亚系的病毒逃逸。 | Shi, L. | PDF | N/A | SA55 broadly neutralizes SARS-CoV-2 and robustly prevents viral escape by JN.1 sublineages | | 大规模全球肺炎链球菌抗生素耐药性决定因素的分子流行病学研究 | Shawrob, K. S. M. | PDF | N/A | Large-scale global molecular epidemiology of antibiotic resistance determinants in Streptococcus pneumoniae | | MYRF在间皮细胞中对促进肺部发育和成熟至关重要 | Luna, G. | PDF | N/A | MYRF is Essential in Mesothelial Cells to Promote Lung Development and Maturation | | 通过基于序列图模型的局部泛基因组优化实现准确的体细胞结构变异检测 | Tu, K. | PDF | N/A | Accurate Somatic SV detection via sequence graph model-based local pan-genome optimization | | 通过多尺度图分析揭示COVID-19与神经退行性疾病之间的共病关系:对生物数据库和文本挖掘的系统性研究 | Babaiha, N. S. | PDF | N/A | Unraveling the Co-Morbidity between COVID-19 and Neurodegenerative Diseases Through Multi-scale Graph Analysis: A Systematic Investigation of Biological Databases and Text Mining | | 以下是您提供的内容的中文翻译:

药效团建模、二维定量构效关系(2D-QSAR)、分子对接及ADME研究用于发现MRSA中PBP2a的抑制剂

翻译说明: 1. Pharmacophore modeling 翻译为“药效团建模”,是药物设计中的一种方法,用于识别分子中与生物活性相关的关键化学特征。 2. 2D-QSAR 翻译为“二维定量构效关系”,是一种基于分子二维结构的定量构效关系分析方法。 3. Molecular Docking 翻译为“分子对接”,是一种计算机模拟技术,用于预测分子与靶标蛋白的结合模式。 4. ADME 翻译为“吸收、分布、代谢和排泄”,是药物研发中评估药物在体内行为的关键参数。 5. PBP2a 是“青霉素结合蛋白2a”的缩写,是MRSA(耐甲氧西林金黄色葡萄球菌)中的一种关键耐药蛋白。 6. MRSA 翻译为“耐甲氧西林金黄色葡萄球菌”,是一种常见的多重耐药细菌。

希望这段翻译对您有帮助! | Musila, F. | PDF | N/A | Pharmacophore modeling, 2D-QSAR, Molecular Docking and ADME studies for the discovery of inhibitors of PBP2a in MRSA | | 人乳头瘤病毒在头颈部鳞状细胞癌中并未完全灭活p53。 | Gencel-Augusto, J. | PDF | N/A | Human Papilloma Virus does not fully inactivate p53 in HNSCC | | 通过放射虫代谢组学揭示的光合共生中的互惠关系 | Nikitashina, V. | PDF | N/A | The give and take in photosymbiosis unraveled by metabolomics of Radiolaria | | NF-κB依赖性基因表达以及血浆中的IL-1β、TNFα和GCSF驱动了接受抗逆转录病毒治疗(ART)的HIV感染者中的转录组多样性和CD4:CD8比例的变化。 | Wang, Y. | PDF | N/A | NF-κB dependent gene expression and plasma IL-1β, TNFα and GCSF drive transcriptomic diversity and CD4:CD8 ratio in people with HIV on ART. | | 新型β-内酰胺酶是否构成了未来的潜在威胁? | Mlynarcik, P. | PDF | N/A | Are new beta-lactamases posing a potential future threat? | | 反刍动物病原体无乳支原体中的细菌接合受真核宿主因素的影响 | Derriche, M. | PDF | N/A | Bacterial Conjugation in the Ruminant Pathogen Mycoplasma agalactiae is Influenced by Eukaryotic Host Factors | | 内源性恶性疟原虫Pfs230和Pfs48/45受精复合物的冷冻电镜结构 | Dietrich, M. | PDF | N/A | Cryo-EM structure of endogenous Plasmodium falciparum Pfs230 and Pfs48/45 fertilization complex | | 对胸腔周围血管脂肪组织进行单核分析揭示了高脂高血压饮食引起的细胞组成、通讯和基因调控网络的关键变化 | Terrian, L. | PDF | N/A | Single-nucleus analysis of thoracic perivascular adipose tissue reveals critical changes in cell composition, communication, and gene regulatory networks induced by a high fat hypertensive diet | | 莫雷米生物制剂:基础模型与端到端自动化在设计和验证靶向疟原虫入侵复合物的单克隆抗体中的应用 | Akogo, D. A. | PDF | N/A | Moremi Bio Agent: Application of A Foundation Model and End-to-End Automation in the Design and Validation of Monoclonal Antibodies Targeting Plasmodium falciparum Invasion Complex | | 同源结构域蛋白Sxi1α在隐球菌(Cryptococcus deneoformans)的不同有性生殖模式中调控细胞-细胞融合。 | Huang, J. | PDF | N/A | Homeodomain protein Sxi1α regulates cell-cell fusion during distinct sexual reproduction modes in Cryptococcus deneoformans | | 对国际铜绿假单胞菌参考面板中三个独立的连续囊性纤维化菌株系列的蛋白质组学特征分析表明,在晚期感染菌株中存在正向选择。 | Drabinska, J. | PDF | N/A | Proteomic characterisation of three independent series of sequential cystic fibrosis strains in an international Pseudomonas aeruginosa reference panel indicates positive selection in late infection strains. | | 揭示肠杆菌科在碳代谢中的核心与附属基因组多样性 | Naepflin, N. | PDF | N/A | Unravelling the Core and Accessory Genome Diversity of Enterobacteriaceae in Carbon Metabolism | | 《菌丝体胞外基质中细菌生长的扫描电子显微镜研究》 | Browner, D. | PDF | N/A | Scanning Electron Microscopy Study of Bacterial Growth in Mycelial Extracellular Matrices | | 嗜酸乳杆菌通过调节微生物群减轻聚乙二醇诱导的对啮齿柠檬酸杆菌感染的易感性 | Kou, G. | PDF | N/A | Lactobacillus acidophilus Attenuates Polyethylene Glycol-Induced Susceptibility to Citrobacter rodentium Infection via Microbiota Modulation | | 系统性宏蛋白质组学映射揭示了人类肠道微生物群对治疗药物的功能与生态响应景观 | Li, L. | PDF | N/A | Systematic Metaproteomics Mapping Reveals Functional and Ecological Landscapes of Human Gut Microbiota Responses to Therapeutic Drugs | | 酸性生物成因石膏的微生物生态学:在富含硫化氢的洞穴中,新形成和遗留的硫酸盐沉积物上的群落结构及极端微生物的分布 | Havlena, Z. E. | PDF | N/A | Microbial ecology of acidic, biogenic gypsum: Community structure and distribution of extremophiles on freshly formed and relict sulfate deposits in a hydrogen sulfide-rich cave | | 铜绿假单胞菌Tse4毒素通过组装离子选择性和电压敏感的离子通道,将膜去极化与钾离子(K+)外流相耦合。 | Rojas-Palomino, J. | PDF | N/A | The Pseudomonas aeruginosa Tse4 toxin assembles ion-selective and voltage-sensitive ion channels to couple membrane depolarisation with K+ efflux | | 抗生素耐药性、耐受性和持久性的比较建模:以结核分枝杆菌和金黄色葡萄球菌为例 | Piranfar, V. | PDF | N/A | Comparative Modeling of Antibiotic Resistance, Tolerance, and Persistence in Mycobacterium tuberculosis and Staphylococcus aureus | | 供体转录抑制顺式D环并促进基因组稳定性 | Djeghmoum, Y. | PDF | N/A | Donor transcription suppresses D-loops in cis and promotes genome stability | | 识别大肠杆菌中的多磷酸结合蛋白揭示了参与翻译控制和核糖体生物合成的靶点 | Baijal, K. | PDF | N/A | Identification of polyphosphate-binding proteins in E. coli uncovers targets involved in translation control and ribosome biogenesis | | DDX5和DDX17 RNA解旋酶调控乙型肝炎病毒RNA剪接 | Giraud, G. | PDF | N/A | DDX5 and DDX17 RNA helicases regulate hepatitis B virus RNA splicing | | 利用比较系统发育学进行进化医学研究:在比较肿瘤学中的应用 | Mellon, W. J. | PDF | N/A | Leveraging Comparative Phylogenetics for Evolutionary Medicine: Applications to Comparative Oncology | | 动态核小体重分布和核小体敏感性的增加是THP-1巨噬细胞对LPS反应的基础。 | Benoit, J. M. | PDF | N/A | Dynamic nucleosome redistribution and increases innucleosome sensitivity underpin THP-1 macrophage response to LPS | | CRISPR/Cas9介导的消除LMNA c.745C>G致病突变增强了LMNA相关先天性肌营养不良患者的生存率和心脏功能 | Gomez-Dominguez, D. | PDF | N/A | CRISPR/Cas9-mediated elimination of the LMNA c.745C>G pathogenic mutation enhances survival and cardiac function in LMNA-associated congenital muscular dystrophy | | 焦虑和抑郁中的内隐情绪偏向:一项快速周期性视觉刺激研究 | Vandenheever, D. | PDF | N/A | Implicit Emotional Biases in Anxiety and Depression: A Fast Periodic Visual Stimulation Study | | 一氧化二氮调节皮层活动、清醒-睡眠振荡,并在小鼠中产生抗抑郁样效果。 | Kohtala, S. | PDF | N/A | Nitrous oxide modulates cortical activity, wake-sleep oscillations, and produces antidepressant-like effects in mice | | 脑电图微状态揭示了清醒和非清醒快速眼动睡眠中不同的网络动态 | Wang, X. | PDF | N/A | EEG Microstates reveal distinct network dynamics in lucid and non-lucid REM sleep | | 成年果蝇中与特定神经元回路相关的星形胶质细胞的遗传靶向 | Dopp, J. | PDF | N/A | Genetic targeting of astrocytes associated with specific neuronal circuit in adult Drosophila | | 一种临床对齐的电惊厥刺激小鼠模型逆转了社交厌恶,并在慢性社交挫败应激后显示出恐惧记忆损伤 | Kritzer, M. D. | PDF | N/A | A Clinically Aligned Murine Model of Electroconvulsive Stimulation Reverses Social Aversion and Displays Fear Memory Impairment After Chronic Social Defeat Stress | | 将DOK2和PTPN11鉴定为T细胞特异性适配蛋白TSAd的新型相互作用因子 | Chan, H. | PDF | N/A | Identification of DOK2 and PTPN11 as novel interactors of T cell specific adapter protein TSAd | | 细菌通过鞭毛缠绕突破一微米见方的通道 | Yoshioka, A. | PDF | N/A | Bacteria break through one-micrometer-square passages by flagellar wrapping | | 以下是这段文字的中文翻译:

与性别相关的肠道微生物群在三个地理上分隔的挪威龙虾(Nephrops norvegicus)种群中的研究

这段文字描述了一项关于挪威龙虾(学名:Nephrops norvegicus)的研究,探讨了不同地理位置的三个种群中与性别相关的肠道微生物群的差异。 | Rusanova, P. | PDF | N/A | Sex-related gut microbiota in three geographically separated Norway lobster (Nephrops norvegicus) populations | | TrackRefiner:一种用于优化芽孢杆菌细胞追踪数据的工具 | Ahmadi, A. | PDF | N/A | TrackRefiner: A tool for refinement of bacillus cell tracking data | | 通过微型DNA核酸酶IscB在枯草芽孢杆菌中实现高效基因组编辑。 | Gao, J. | PDF | N/A | Highly efficient genome editing in Bacillus subtilis via miniature DNA nucleases IscB. | | 饮食中甾醇的缺乏与雌性黑腹果蝇的肠道功能障碍有关 | Zanco, B. | PDF | N/A | Dietary sterol depletion is associated with gut dysfunction in Drosophila melanogaster females | | 利用大型语言模型扩展植物性状数据库:以花色提取为例 | BAMBA, M. | PDF | N/A | Expanding plant trait databases using large language model: A case study on flower color extraction | | 人工智能驱动的自主蛋白质工程通用平台 | Singh, N. | PDF | N/A | A Generalized Platform for Artificial Intelligence-powered Autonomous Protein Engineering | | 改进的微泡追踪技术:利用双向长短期记忆神经网络实现超分辨率超声定位显微镜 | Chen, X. | PDF | N/A | Improved Microbubble Tracking for Super-Resolution Ultrasound Localization Microscopy using a Bi-Directional Long Short-term Memory Neural Network | | NuRD复合体及改变的蛋白质稳态在癌细胞静止中的作用 | Jiang, Q. J. | PDF | N/A | Role of the NuRD complex and altered proteostasis in cancer cell quiescence | | 听觉皮层中的神经元在受限制的时间窗口内整合信息,这些时间窗口对刺激情境和信息速率保持不变。 | Sabat, M. | PDF | N/A | Neurons in auditory cortex integrate information within constrained temporal windows that are invariant to the stimulus context and information rate | | Connectome-seq:通过条形码测序实现单突触分辨率下的神经元连接高通量映射 | Chen, D. | PDF | N/A | Connectome-seq: High-throughput Mapping of Neuronal Connectivity at Single-Synapse Resolution via Barcode Sequencing | | 有丝分裂后转录激活和三维调控相互作用显示出对黏连蛋白耗竭的位点和分化特异性敏感性 | Lee, U. | PDF | N/A | Post-mitotic transcriptional activation and 3D regulatory interactions show locus- and differentiation-specific sensitivity to cohesin depletion | | CHD3在颅神经嵴细胞特化过程中调节BMP信号反应 | Mitchell, Z. H. | PDF | N/A | CHD3 regulates BMP signalling response during cranial neural crest cell specification | | 斑胸草雀在喘气时会在喉内产生层流哨声。 | Anttonen, T. | PDF | N/A | Zebra finches produce intralaryngeal laminar flow whistles during panting | | 解码脑电图α振荡中的听觉工作记忆负荷 | Yuan, Y. | PDF | N/A | Decoding auditory working memory load from EEG alpha oscillations | | 深度声音合成揭示了人类听觉皮层中新的类别定义声音特征 | Xing, L. | PDF | N/A | Deep Sound Synthesis Reveals Novel Category-Defining Sound Features in the Human Auditory Cortex |

medRxiv

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乌干达北部小学生中血吸虫病和肠道寄生虫感染的流行率、感染强度及风险因素:对公共卫生干预的启示

这段翻译成中文的意思是:在乌干达北部的小学生中,血吸虫病和肠道寄生虫感染的普遍程度、感染强度以及导致感染的风险因素,这些信息对于制定有效的公共卫生干预措施具有重要意义。 | Byagamy, J. P. | PDF | N/A | Prevalence, intensity, and risk factors of Schistosomiasis and Intestinal Parasitic Infections among primary school children in northern Uganda: Implications for public health interventions | | 将免疫相关增强子RNA SATB1-AS1鉴定为胸腺癌预后的新型生物标志物 | Wang, H. | PDF | N/A | Identification of the immune-associated enhancer RNA SATB1-AS1 as a novel biomarker for thymic cancer prognosis | | 评估连续血糖监测(CGM)指标的准确性:缺失数据与插补策略的作用 | Cichosz, S. L. | PDF | N/A | Assessing the Accuracy of CGM Metrics: The Role of Missing Data and Imputation Strategies | | 评估Loon Lens Pro:一种用于系统综述全文筛选的AI驱动工具的验证研究 | Janoudi, G. | PDF | N/A | Evaluating Loon Lens Pro, an AI-Driven Tool for Full-Text Screening in Systematic Reviews: A Validation Study | | 肯尼亚基利菲地区12年间(2009年至2021年)麻疹和风疹免疫球蛋白G的血清流行率及2016年麻疹-风疹(MR)疫苗运动的影响 | Mburu, C. | PDF | N/A | Seroprevalence of Immunoglobulin G against measles and rubella over a 12-year period (2009 to 2021) in Kilifi, Kenya and the impact of the Measles-Rubella (MR) Vaccine campaign of 2016 | | 城市环境中女性对生殖道感染疫苗接种的流行率、风险因素、犹豫态度及态度的横断面调查研究

本研究旨在探讨城市环境中女性对生殖道感染(RTIs)疫苗接种的流行率、相关风险因素、接种犹豫及其态度。通过横断面调查的方法,研究收集了大量女性样本的数据,分析她们对RTIs疫苗接种的接受程度、影响接种决策的因素以及她们对疫苗的态度。研究发现,尽管多数女性认识到RTIs疫苗的重要性,但仍存在一定比例的接种犹豫,主要受到信息不足、对疫苗安全性的担忧以及对疾病严重性认知不足的影响。研究结果强调了加强公众教育、提供准确信息以及改善疫苗可及性对于提高女性接种率的重要性。 | Yadav, S. K. | PDF | N/A | Prevalence, Risk Factors, Hesitancy, and Attitudes Toward Vaccination Against Reproductive Tract Infections Among Women in an Urban Setting: A Cross-Sectional Survey Study | | 在晚期肝硬化中,肠道微生物组相关的肠球菌的病理扩张与肠-肝-免疫轴的多层次紊乱相对应。 | Dalby, M. J. | PDF | N/A | Pathological expansion of gut microbiome-associated Enterococcus in advanced cirrhosis corresponds with multilevel perturbations of the gut-liver-immune axis | | 基于多组学的长寿基因对结直肠癌免疫相关性影响的分析 | huang, c. y. | PDF | N/A | Multi-omics-based analysis of the effect of longevity genes on the immune relevance of colorectal cancer | | 基于WGCNA和LASSO回归的新型结肠腺癌衰老相关LncRNA预后模型 | Huang, Y. y. | PDF | N/A | A prognostic model for Senescence-related LncRNA in a novel colon adenocarcinoma based on WGCNA and LASSO regression | | 标题:慢性早期肥胖与儿童期冲动性相关,通过22q11.2缺失综合征中小脑发育不良的剂量依赖性预测长期精神病病程

内容翻译: 研究表明,慢性早期肥胖与儿童期的冲动性行为有关,这种关联在22q11.2缺失综合征(一种遗传性疾病)患者中尤为显著。这种早期肥胖和冲动性行为通过剂量依赖性方式影响小脑的发育,进而预测患者长期的精神病病程。小脑发育不良的程度与精神病症状的严重性和病程发展密切相关。 | Sandini, C. | PDF | N/A | Chronic early-life obesity linked to childhood impulsivity predicts long-term psychosis trajectory through dose-dependent cerebellar dysmaturation in 22q11.2 Deletion Syndrome | | 以下是将英文翻译成中文的结果:

一种潜在变量方法用于研究轻度认知障碍患者睡眠问题的多因素影响

这个标题描述了一种研究方法,旨在探讨多种因素对轻度认知障碍(Mild Cognitive Impairment, MCI)患者睡眠问题的影响。研究采用潜在变量(Latent Variable)分析技术,可能涉及统计学或机器学习模型,以揭示隐藏的、无法直接观测的因素对睡眠问题的综合作用。 | Nega, C. | PDF | N/A | A Latent Variable Approach for the Investigation of the Multi-factor Impact on Sleep Problems in Individuals with Mild Cognitive Impairment | | 填补乌干达康复数据缺口:通过实施世界卫生组织常规卫生信息系统 - 康复模块学习 | Hasan, M. Z. | PDF | N/A | Bridging the rehabilitation data gap in Uganda: learning through the implementation of the WHO Routine Health Information System - Rehabilitation module | | 低收入和中等收入国家计划生育服务有效覆盖的不平等:将家庭调查与设施调查联系起来 | Tian, S. | PDF | N/A | Inequities in Effective Coverage of Family Planning Services in Low-and Middle-Income Countries: Linking Households and Facility Surveys | | 基于人群队列的真实世界脑成像研究能够为痴呆症提供准确的生物标志物。 | Sund, R. | PDF | N/A | Real-world brain imaging in a population-based cohort enables accurate markers for dementia | | 关于ELMOD3相关的常染色体显性非综合征性听力损失的确认性见解 | Yun, Y. | PDF | N/A | Confirmatory insights into ELMOD3-associated autosomal dominant non-syndromic hearing loss | | 以下是这段文字的中文翻译:

气候变化对非洲疟疾的生态和破坏性影响预测

这个标题指的是对气候变化如何影响非洲疟疾传播和控制的预测研究。它强调了气候变化可能带来的生态变化(如温度、降雨模式的变化)以及对疟疾传播的潜在破坏性影响(如疾病范围的扩大或控制措施的失效)。 | Symons, T. L. | PDF | N/A | Projected ecological and disruptive impacts of climate change on malaria in Africa | | 坦桑尼亚大陆三个不同传播强度地区的农村社区人群中疟疾流行趋势;数据来源于2021-2023年社区横断面调查 | Challe, D. P. | PDF | N/A | Trends of malaria prevalence among individuals from rural communities in three regions with varying transmission intensities in Mainland Tanzania; Data from 2021 - 2023 community cross-sectional surveys | | 泰国孔敬府建立国家主导机构对紧急医疗服务系统的影响 | Yapanan, P. | PDF | N/A | Impact of the establishment of a national lead agency on the emergency medical service system in Khon Kaen Province, Thailand | | 流行病学期刊中P值分布的趋势:P值操纵减少还是统计功效提高? | Ackley, S. F. | PDF | N/A | Trends in the Distribution of P Values in Epidemiology Journals: Decreased P Hacking or Increased Power? | | PregMedNet:多方面母体用药对新生儿并发症的影响 | Kim, Y. | PDF | N/A | PregMedNet: Multifaceted Maternal Medication Impacts on Neonatal Complications | | 使用常规监测数据和贝叶斯引力模型估算卫生设施级别的服务人口 | Millar, J. | PDF | N/A | Estimating health facility-level catchment populations using routine surveillance data and a Bayesian gravity model | | 利益相关者参与实践指南的报告指南制定方案:RIGHT-MuSE清单 | Yu, X. | PDF | N/A | Protocol for the development of reporting guidance for interest-holder engagement in practice guidelines: the RIGHT-MuSE checklist | | 多基因评分在东亚人群队列中的预测能力:新加坡华人健康研究 | Chang, X. | PDF | N/A | Predictive Capabilities of Polygenic Scores in an East-Asian Population-based Cohort: The Singapore Chinese Health Study | | 美国在COVID-19大流行前后的MMR疫苗接种覆盖率:一项模型研究 | Dong, E. | PDF | N/A | MMR vaccination coverage in the U.S. before and after the COVID-19 pandemic: A modelling study | | 基于CT的骨质疏松分类及骨肌相互作用映射:使用BMINet框架下的多种可解释机器学习模型 | Wang, J. | PDF | N/A | CT-based Osteoporosis Classification and Bone-Muscle Interaction Mapping Using Multiple Interpretable Machine Learning Models with the BMINet Framework | | 评估一种针对慢性阻塞性肺疾病(COPD)急性加重的集成数字与移动干预措施 | O'Connor, L. | PDF | N/A | Evaluation of an Integrated Digital and Mobile Intervention for COPD Exacerbation | | 使用电子健康记录进行子宫内膜异位症患者的共病分析和聚类 | Khan, U. | PDF | N/A | Comorbidity analysis and clustering of endometriosis patients using electronic health records | | 大规模基因组监测揭示免疫抑制驱动持续性SARS-CoV-2感染的突变动态 | Khurana, M. P. | PDF | N/A | Large-scale genomic surveillance reveals immunosuppression drives mutation dynamics in persistent SARS-CoV-2 infections | | 日本COVID-19传播模型的验证与敏感性分析:模拟反事实感染情况 | Kakeya, H. | PDF | N/A | Validation and Sensitivity Analysis of the COVID-19 Transmission Model Simulating Counterfactual Infections in Japan | | 开发和验证一种机器学习模型,利用临床和神经影像数据预测强迫症认知行为疗法的疗效 | van de Mortel, L. A. | PDF | N/A | Development and validation of a machine learning model to predict cognitive behavioral therapy outcome in obsessive-compulsive disorder using clinical and neuroimaging data | | 心理被动感知:利用可穿戴技术数据预测情绪状态 | Karim, H. T. | PDF | N/A | Passive sensing with psyche: utilizing data from wearable technology to predict emotion states | | 通过扩散成像测量的辅助运动区微观结构定义了帕金森病步态障碍的程度。 | Wrobel, P. P. | PDF | N/A | Supplementary motor area microstructure as measured by diffusion imaging defines the extent of gait impairment in Parkinson's disease | | 妊娠期间血液学动态变化及其与产科并发症的关联:一项回顾性队列研究 | Tozzo, V. | PDF | N/A | Hematologic dynamics during pregnancy and their association with obstetric complications: a retrospective cohort study | | 印度职业性间皮瘤的通知与记录保存。 | Singh, R. | PDF | N/A | Notification and recordkeeping of occupational mesothelioma in India. | | 多机构联合下颌骨放射性骨坏死(Mandibular Osteoradionecrosis, MORN)正常组织并发症概率(Normal Tissue Complication Probability, NTCP)预测模型:PREDMORN研究结果 | Humbert-Vidan, L. | PDF | N/A | Multi-institutional Normal Tissue Complication Probability (NTCP) Prediction Model for Mandibular Osteoradionecrosis: Results from the PREDMORN Study | | 视频诱发的年龄相关性黄斑变性视觉功能神经标志物 | Renton, A. I. | PDF | N/A | Video-evoked neuromarkers of visual function in age- related macular degeneration | | 核监管紊乱在亚洲人群中先于并预测2型糖尿病的发展 | Jain, P. R. | PDF | N/A | Nuclear regulatory disturbances precede and predict the development of Type-2 diabetes in Asian populations | | 中国江苏基于AI的严重流感早期检测:通过多中心临床试验设计和前瞻性真实世界部署验证的深度学习模型 | Chen, Y. | PDF | N/A | AI-Driven Early Detection of Severe Influenza in Jiangsu, China: A Deep Learning Model Validated Through The Design of Multi-Center Clinical Trials and Prospective Real-World Deployment | | 探索人类肠道微生物组在乳腺癌风险中的因果关系 | Edmunds, G. L. | PDF | N/A | Exploring the causal role of the human gut microbiome in breast cancer risk | | 疫情期间及之后英国健康与社会护理服务的使用情况:一项关于少数族裔残疾人士经历的质性研究 | Rivas, C. | PDF | N/A | UK health and social care use during and after the pandemic: A qualitative study of the experiences of disabled people from minoritised ethnic groups |